PRODUCT DETAILS

About Trigetrol Tablet

GLIBENCLAMIDE+METFORMIN+ROSIGLITAZONE belongs to a class of medicines called antidiabetic drugs used in the treatment of type 2 diabetes, especially in patients whose blood sugar levels are not controlled by diet and exercise alone. Type 2 diabetes is a chronic (long-lasting) condition that affects the way our body processes glucose. People with type 2 diabetes either do not produce enough insulin or the insulin produced is unable to perform its function in the body (insulin resistance).

Uses of Trigetrol Tablet

Type 2 diabetes mellitus

Medicinal Benefits of Trigetrol Tablet

GLIBENCLAMIDE+METFORMIN+ROSIGLITAZONE contains three antidiabetic drugs (Glibenclamide, Metformin and Rosiglitazone) used in the treatment of type 2 diabetes. Glibenclamide stimulates cells in the pancreas that produce insulin which helps to remove sugar from the blood. Metformin reduces the sugar production by cells in the liver and delays sugar absorption from the intestines. Also, it increases the sensitivity of muscle cells to insulin which enables these cells to remove sugar more effectively from the blood. Rosiglitazone increases the sensitivity of liver, muscle and fat cells to insulin and enables cells to remove glucose from blood more effectively. Also, it decreases the amount of glucose produced by the liver and preserves the functioning of beta cells in the pancreas that produce insulin. Thereby, GLIBENCLAMIDE+METFORMIN+ROSIGLITAZONE helps to control blood sugar levels.

Directions for Use

Take GLIBENCLAMIDE+METFORMIN+ROSIGLITAZONE with food to avoid stomach upset as advised by your doctor. GLIBENCLAMIDE+METFORMIN+ROSIGLITAZONE should be swallowed as a whole with a glass of water. Do not crush or break it.

Side Effects of Trigetrol Tablet

• Stomach pain
• Nausea
• Diarrhoea
• Vomiting
• Headache
• Low blood sugar

Similar Drugs

For informational purposes only. Consult a doctor before taking any medicines.

In-Depth Precautions and Warning

Drug Warnings

If you are allergic to GLIBENCLAMIDE+METFORMIN+ROSIGLITAZONE or any other medicines, please tell your doctor. GLIBENCLAMIDE+METFORMIN+ROSIGLITAZONE is not recommended for children. Avoid breastfeeding while taking GLIBENCLAMIDE+METFORMIN+ROSIGLITAZONE as it may be excreted in human milk. If you are pregnant or planning for pregnancy, please inform your doctor before taking GLIBENCLAMIDE+METFORMIN+ROSIGLITAZONE as it may harm the unborn baby. GLIBENCLAMIDE+METFORMIN+ROSIGLITAZONE should be used with caution in elderly patients. Avoid alcohol consumption with GLIBENCLAMIDE+METFORMIN+ROSIGLITAZONE as it may increase the risk of lactic acidosis (accumulation of lactic acid in the body). Drive only if you are alert after taking GLIBENCLAMIDE+METFORMIN+ROSIGLITAZONE. Take short, frequent meals and avoid prolonged fasting while taking GLIBENCLAMIDE+METFORMIN+ROSIGLITAZONE. Beware of symptoms of hypoglycaemia (low blood sugar) which include sweating, dizziness, palpitations, shivering, intense thirst, dry mouth, dry skin, frequent urination etc. Whenever you experience any of these symptoms, immediately consume 5-6 candies or 3 glucose biscuits or 3 teaspoons of honey/sugar and also consult your doctor. Make sure to carry these with you at all times, especially during long travels.

Drug Interactions

Drug-Drug Interaction:

 GLIBENCLAMIDE+METFORMIN+ROSIGLITAZONE may have interaction with drugs used to treat high blood pressure in lungs (bosentan), other antidiabetic drugs (insulin, sitagliptin), water pill (furosemide), antithyroid drugs (levothyroxine), anticonvulsant (pregabalin).

Drug-Disease Interaction:

If you have type 1 diabetes, lactic acidosis, diabetic ketoacidosis (accumulation of ketone bodies in the blood), eye problems caused by diabetes, liver, kidney or heart problems, inform your doctor before taking GLIBENCLAMIDE+METFORMIN+ROSIGLITAZONE.

Safety Advice

ALCOHOL

You are recommended to avoid consumption of alcohol with GLIBENCLAMIDE+METFORMIN+ROSIGLITAZONE as it may increase the risk of lactic acidosis (accumulation of lactic acid in the body).

PREGNANCY

GLIBENCLAMIDE+METFORMIN+ROSIGLITAZONE is not recommended for pregnant women as it may harm an unborn baby. Please consult a doctor if you are pregnant or planning for pregnancy.

BREAST FEEDING

Avoid breastfeeding while taking GLIBENCLAMIDE+METFORMIN+ROSIGLITAZONE as it may be excreted in breastmilk and cause adverse effects in the baby. Therefore, please consult a doctor before using GLIBENCLAMIDE+METFORMIN+ROSIGLITAZONE if you are breastfeeding.

DRIVING

GLIBENCLAMIDE+METFORMIN+ROSIGLITAZONE may decrease alertness in some people. Therefore, drive only if you are alert after taking GLIBENCLAMIDE+METFORMIN+ROSIGLITAZONE.

LIVER

Take GLIBENCLAMIDE+METFORMIN+ROSIGLITAZONE with caution, especially if you have a history of liver diseases/conditions. The dose may be adjusted by your doctor as required.

KIDNEY

Take GLIBENCLAMIDE+METFORMIN+ROSIGLITAZONE with caution, especially if you have a history of kidney diseases/conditions. The dose may be adjusted by your doctor as required.