PRODUCT DETAILS

About Topgene 25mg Tablet

TOPIRAMATE belongs to a group of medicines called “antiepileptic (AED)/ anticonvulsant agent' that is primarily indicated in the treatment of epilepsy (Monotherapy and Adjunctive therapy) and It can also be taken to prevent migraine. Epilepsy is a chronic disorder that is responsible for causing unprovoked, recurrent seizures in the body. A seizure is a sudden attack in the brain that makes a person lose control of their actions. Migraine is a mental condition that often causes intense or debilitating headaches with difficulty speaking, nausea, vomiting, and sensitivity to light or sound.

TOPIRAMATE is responsible for restoring the balance of neural activity by diminishing the spread of seizure movement in the brain. By controlling the electrical activity of the brain, it controls seizures and relieves the symptoms of migraine. Take TOPIRAMATE in an empty stomach without food with one glass of water. TOPIRAMATE is only available on prescription. It comes as tablets or capsules intended to be taken by mouth only. Swallow the medication as a whole without crushing or breaking it. TOPIRAMATE doses are sometimes advised according to the weight of children so the doctor will change the dose if the child gains or lose weight.

Uses of Topgene 25mg Tablet

Epilepsy, Migraine

Medicinal Benefits of Topgene 25mg Tablet

TOPIRAMATE is an antiepileptic (AED) medicine that is used to treat epilepsy in mono or adjunctive therapy and migraine. In Monotherapy epilepsy, TOPIRAMATE is suggested for patients above 2 years of age with partial-onset or primary generalized tonic-clonic seizures. In Adjunctive therapy epilepsy, TOPIRAMATE is suggested in patients of 2 to 16 years of age with partial-onset seizures or primary generalized tonic-clonic seizures while in patients more than 2 years of age, TOPIRAMATE is suggested in patients with seizures associated with Lennox-Gastaut syndrome (LGS). In migraine, TOPIRAMATE is suggested for prophylaxis of migraine. TOPIRAMATE works by blocking the voltage-dependent sodium and calcium channels and increasing the inhibitory actions of GABA. In epilepsy, TOPIRAMATE controls the uncontrolled activity of nerves in the brain and thus prevents or controls seizures. While in migraine, TOPIRAMATE tranquilizes the overactive nerve cells in the brain that are responsible for causing migraine.

Directions for Use

Tablet: It can be taken irrespective of meals. Swallow the tablet as a whole with a glass of water. Do not chew the tablet. Sprinkle capsule: You may swallow the capsule as a whole or you may open the capsule and sprinkle the entire contents on a teaspoon of soft food. Drink fluids immediately after eating this medicine and food mixture to make sure it is swallowed. Do not store this mixture for later use.

Side Effects of Topgene 25mg Tablet

• Tingling of the arms and legs
• Not feeling hungry
• Nausea
• Change in taste
• Diarrhoea
• Weight loss
• Nervousness
• Upper respiratory tract infection

Similar Drugs

For informational purposes only. Consult a doctor before taking any medicines.

In-Depth Precautions and Warning

Drug-Drug Interaction:

A person should tell the doctor about all the medications they are using, including the medicines used to treat diabetes (metformin, glibenclamide, pioglitazone), medicines used to treat depression or anxiety  (venlafaxine, amitriptyline), medicines for heart or blood pressure (diltiazem, hydrochlorothiazide, propranolol), antipsychotic medicines (risperidone), and or any other epilepsy medicines.

Safety Advice

ALCOHOL

Do not consume alcohol while taking TOPIRAMATE as alcohol can worsen the side effects of the TOPIRAMATE including sleepiness and dizziness

BREAST FEEDING

Caution is advised when TOPIRAMATE is using in nursing mothers as this medicine may pass into breast milk.

DRIVING

Some persons may continue to face unpredictable seizures even after taking TOPIRAMATE and this medicine also affects thinking and motor skills and may affect vision. So patients should take caution before engaging in any activity including driving or operating any machine.

LIVER

TOPIRAMATE should be used with caution in patients with liver disease as the dosage needs to be reduced in patients dealing with liver disease.

KIDNEY

TOPIRAMATE should be used with caution in patients with kidney disease as the dosage needs to be reduced in patients dealing with kidney disease.