PRODUCT DETAILS

About Thiofem AP 4mg/100mg/325mg Tablet

ACECLOFENAC+PARACETAMOL+THIOCOLCHICOSIDE is a combination medicine used to relieve pain and inflammation associated with osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, muscle pain, bone and joint pain. Pain is a symptom triggered by the nervous system, causing uncomfortable sensations in the body. Muscle spasm is the sudden involuntary contractions of the muscle, which can be painful and uncomfortable. Arthritis is the tenderness and swelling in the joints.

ACECLOFENAC+PARACETAMOL+THIOCOLCHICOSIDE is a combination of three drugs, namely: Thiocolchicoside (muscle relaxant), Aceclofenac (NSAID), and Paracetamol (Analgesic). Thiocolchicoside works on the centres of the spinal cord and brain. This helps relieve muscle stiffness and improves muscle movements. Aceclofenac and Paracetamol work by blocking the effect of a chemical messenger known as cyclo-oxygenase (COX) enzymes that make another chemical prostaglandin (PG). These prostaglandins are produced at injury sites and cause pain and swelling. By blocking COX enzymes' effect, lesser PGs are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site. Together, ACECLOFENAC+PARACETAMOL+THIOCOLCHICOSIDE helps in relieving pain due to muscle spasms.

Uses of Thiofem AP 4mg/100mg/325mg Tablet

Pain and Inflammation associated with musculoskeletal and joint disorders.

Medicinal Benefits of Thiofem AP 4mg/100mg/325mg Tablet

ACECLOFENAC+PARACETAMOL+THIOCOLCHICOSIDE is a combination of three drugs, namely: Thiocolchicoside, Aceclofenac, and Paracetamol. ACECLOFENAC+PARACETAMOL+THIOCOLCHICOSIDE is a combination medicine used to relieve pain and inflammation associated with osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, muscle pain, bone and joint pain. ACECLOFENAC+PARACETAMOL+THIOCOLCHICOSIDE increases the pain threshold and blood flow across the skin. Thiocolchicoside is a muscle relaxant which works on the centres of spinal cord and brain. This helps relieve muscle stiffness and improves muscle movements. Aceclofenac and Paracetamol are analgesics which work by blocking the effect of a chemical messenger known as cyclo-oxygenase (COX) enzymes that make another chemical prostaglandins (PG). These prostaglandins are produced at injury sites and cause pain and swelling. By blocking COX enzymes' effect, lesser PGs are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site. Together, ACECLOFENAC+PARACETAMOL+THIOCOLCHICOSIDE helps in relieving pain due to muscle spasms.

Directions for Use

Take ACECLOFENAC+PARACETAMOL+THIOCOLCHICOSIDE with or without food. Swallow ACECLOFENAC+PARACETAMOL+THIOCOLCHICOSIDE as a whole with a glass of water; do not chew, or break the table. Based on your medical condition, your doctor will decide how long you need to take ACECLOFENAC+PARACETAMOL+THIOCOLCHICOSIDE.

Side Effects of Thiofem AP 4mg/100mg/325mg Tablet

• Nausea
• Vomiting
• Stomach pain
• Diarrhoea
• Loss of appetite
• Heartburn

Similar Drugs

For informational purposes only. Consult a doctor before taking any medicines.

In-Depth Precautions and Warning

Drug-Drug Interaction:

ACECLOFENAC+PARACETAMOL+THIOCOLCHICOSIDE may have interaction with pain killers (aspirin, ibuprofen, naproxen, celecoxib, etoricoxib), anti-depressants (citalopram, escitalopram, fluoxetine, fluvoxamine, paroxetine, sertraline, lithium), cardiac glycoside (digoxin), anti-hypertensives (enalapril, lisinopril, losartan, candesartan, hydralazine, methyldopa, clonidine, moxonidine, propranolol), antibiotics (ciprofloxacin, ofloxacin, levofloxacin moxifloxacin), diuretics (furosemide, amiloride hydrochloride), blood thinners (warfarin, heparin, clopidogrel), anti-rheumatoid (methotrexate), steroids (mifepristone), glucocorticoids (hydrocortisone, prednisolone), immunosuppressants (ciclosporin, tacrolimus), anti-HIV (zidovudine), anti-diabetic (glibenclamide, gliclazide, tolbutamide).

Safety Advice

ALCOHOL

Avoid consumption of alcohol while taking ACECLOFENAC+PARACETAMOL+THIOCOLCHICOSIDE as it may increase drowsiness. It can also increase the risk of stomach bleeding.

DRIVING

ACECLOFENAC+PARACETAMOL+THIOCOLCHICOSIDE may cause dizziness and drowsiness. Do not drive or operate machinery unless you are alert.

LIVER

Dose adjustment may be needed in patients with liver impairment.

KIDNEY

Dose adjustment may be needed in patients with Kidney impairment.