PRODUCT DETAILS

About Sired Tablet

ACECLOFENAC+SERRATIOPEPTIDASE belongs to a group of medicines called 'Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) used to provide pain relief in various conditions including post-traumatic pain, low back pain, cervical pain, spondylitis, osteoarthritis, rheumatoid arthritis. Pain can be temporary (acute) or prolonged period (chronic) in nature. Acute pain is for a short time caused by damage to the tissues of the muscle, bone, or organs. Chronic pain lasts for life long caused due to nerve damage, osteoarthritis, and dental pain due to damage to the tooth nerve, infection, extraction, or injury. 

ACECLOFENAC+SERRATIOPEPTIDASE contains two medicines, namely Aceclofenac and Serratiopeptidase. Aceclofenac works by blocking the release of a chemical messenger called prostaglandin, produced by COX-2, responsible for pain, swelling, and inflammation. On the other hand, Serratiopeptidase is a proteolytic enzyme that helps break the insoluble protein (fibrin) by-product of blood clots into smaller units. It also causes thinning of the fluids in the body due to injury, thereby making fluid drainage smoother in the swollen tissue. Together ACECLOFENAC+SERRATIOPEPTIDASE is effective for relieving pain, especially in joint conditions. 

You are advised to take ACECLOFENAC+SERRATIOPEPTIDASE for as long as your doctor has prescribed it for you depending on your medical conditions. You may experience nausea, vomiting, loss of appetite (feeling not hungry), heartburn, stomach pain, indigestion, and diarrhea. Most of these side effects of ACECLOFENAC+SERRATIOPEPTIDASE do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Do not take ACECLOFENAC+SERRATIOPEPTIDASE if you are pregnant or breastfeeding unless prescribed by the doctor. ACECLOFENAC+SERRATIOPEPTIDASE may cause drowsiness and dizziness, so drive with caution. ACECLOFENAC+SERRATIOPEPTIDASE should not be given to children as safety and efficacy have not been established. Avoid consuming alcohol, and ACECLOFENAC+SERRATIOPEPTIDASE as it could lead to increased drowsiness and dizziness; it might also increase stomach bleeding risk. ACECLOFENAC+SERRATIOPEPTIDASE should not be given to children as safety and effectiveness were not established. 

Uses of Sired Tablet

Musculoskeletal pain, Gout, Osteoarthritis, Rheumatoid arthritis, Ankylosing spondylitis

Medicinal Benefits of Sired Tablet

ACECLOFENAC+SERRATIOPEPTIDASE is used to provide pain relief in various conditions including post-traumatic pain, low back pain, cervical pain, spondylitis (inflammation in spinal bones), osteoarthritis (lifelong joint pain and stiffness), rheumatoid arthritis (joint pain and damage throughout the body), and migraine. ACECLOFENAC+SERRATIOPEPTIDASE plays a vital role in reducing pain and inflammation by blocking the release of chemical messengers that cause pain and inflammation. This helps in reducing mild to moderate pain and inflammation at the injured or damaged site. Serratiopeptidase is a proteolytic enzyme that helps break the insoluble protein (fibrin) by-product of blood clots into smaller units. It also causes thinning of the fluids in the body due to injury, thereby making fluid drainage smoother in the swollen tissue.

Directions for Use

ACECLOFENAC+SERRATIOPEPTIDASE is available in the form of a tablet. ACECLOFENAC+SERRATIOPEPTIDASE is swallowed as a whole with a glass of water. Do not crush, chew or break them. Your doctor prescribes the dose and duration. It is usually taken with food. It is advisable to take tablets at a fixed time every day.

Side Effects of Sired Tablet

• Nausea
• Vomiting
• Loss of appetite
• Heartburn
• Stomach pain
• Indigestion
• Diarrhea

Similar Drugs

For informational purposes only. Consult a doctor before taking any medicines.

In-Depth Precautions and Warning

Drug Warnings

ACECLOFENAC+SERRATIOPEPTIDASE can increase your risk of fatal heart attack or stroke. So, if you have had any recent heart surgery, do not use ACECLOFENAC+SERRATIOPEPTIDASE. Do not take ACECLOFENAC+SERRATIOPEPTIDASE if you are allergic to ACECLOFENAC+SERRATIOPEPTIDASE or other pain killers. ACECLOFENAC+SERRATIOPEPTIDASE should not be taken in the conditions like stomach ulcers, bleeding problems, clotting problems, severe heart, liver, or kidney problems. Inform your doctor before taking ACECLOFENAC+SERRATIOPEPTIDASE if you have or had disorders of the stomach, blood circulation problems to the brain, asthma, angioedema (swelling under the skin), skin rashes, diabetes, high blood pressure, auto-immune diseases, connective tissue diseases. Stop taking ACECLOFENAC+SERRATIOPEPTIDASE and consult your doctor immediately if you have stomach pain or any signs of bleeding in the intestine or stomach such as blood in stools. Inform your doctor if you are recovering from major surgery or if you are more than 65 years of age. Do not take ACECLOFENAC+SERRATIOPEPTIDASE if you are pregnant or breastfeeding unless prescribed. ACECLOFENAC+SERRATIOPEPTIDASE may cause drowsiness and dizziness, so drive only if you are alert. ACECLOFENAC+SERRATIOPEPTIDASE should not be given to children as safety has not been established. Avoid consuming alcohol along with ACECLOFENAC+SERRATIOPEPTIDASE as it could lead to increased drowsiness and can increase the risk of stomach bleeding.

Drug Interactions

Drug-Drug Interaction:

ACECLOFENAC+SERRATIOPEPTIDASE may have interaction with pain killers (aspirin, ibuprofen, naproxen, celecoxib, etoricoxib), anti-depressants (citalopram, escitalopram, fluoxetine, fluvoxamine, paroxetine, sertraline, lithium), cardiac glycoside (digoxin), anti-hypertensives (enalapril, lisinopril, losartan, candesartan, hydralazine, methyldopa, clonidine, moxonidine, propranolol), blood thinners (warfarin, heparin, clopidogrel), anti-rheumatoid (methotrexate), steroids (mifepristone).

Drug-Disease Interaction:

ACECLOFENAC+SERRATIOPEPTIDASE should be used with caution in patients with stomach ulcers or bleeding, severe kidney disease, liver diseases, and colitis (inflammation of the large intestine).

Safety Advice

ALCOHOL

You are recommended not to consume alcohol along with ACECLOFENAC+SERRATIOPEPTIDASE to avoid unpleasant side effects like increased risk of stomach bleeding.

PREGNANCY

The use of ACECLOFENAC+SERRATIOPEPTIDASE may impair female fertility and is not recommended in pregnant women or those planning for pregnancy.

BREAST FEEDING

ACECLOFENAC+SERRATIOPEPTIDASE contains serratiopeptidase, which may pass into the breast milk. So, it is not recommended for nursing mothers.

DRIVING

ACECLOFENAC+SERRATIOPEPTIDASE may affect driving as it causes dizziness. So do not drive a motor vehicle or operate heavy machinery after taking ACECLOFENAC+SERRATIOPEPTIDASE.

LIVER

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

KIDNEY

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.