PRODUCT DETAILS

About Rebzed LS 75mg/20mg Capsule

LEVOSULPIRIDE+RABEPRAZOLE belongs to a group of medicines called gastrointestinal agents used to treat gastro-oesophageal reflux disease (GERD), acidity, heartburn, Zollinger-Ellison syndrome, Helicobacter pylori infection, irritable bowel syndrome, indigestion, duodenal and gastric ulcers. The stomach is usually protected from the acid by a mucous layer. In some cases, due to excess acid production, the mucous layer gets eroded, which leads to acidity. SR form sustains the release of drugs for a prolonged period of time.
 

Uses of Rebzed LS 75mg/20mg Capsule

Gastro-oesophageal reflux disease, acidity, indigestion heartburn, and peptic ulcers.

Medicinal Benefits of Rebzed LS 75mg/20mg Capsule

LEVOSULPIRIDE+RABEPRAZOLE is a combination of two drugs, namely: Rabeprazole and Levosulpiride. LEVOSULPIRIDE+RABEPRAZOLE belongs to a group of medicines called gastrointestinal agents used to treat gastro-oesophageal reflux disease (GERD), acidity, heartburn, Zollinger-Ellison syndrome, Helicobacter pylori infection, irritable bowel syndrome, indigestion, duodenal and gastric ulcers. Rabeprazole is a proton pump inhibitor that works by blocking an enzyme called gastric proton pump, which is responsible for the production of acid. Levosulpiride is a prokinetic agent that increases the pressure of the inferior oesophageal (food pipe) sphincter, thereby preventing the backflow of food and acid into the mouth. Together, LEVOSULPIRIDE+RABEPRAZOLE helps in preventing acid reflux, thereby provides relief from acidity and heartburn. SR form sustains the release of drugs for a prolonged period of time.

Directions for Use

Take LEVOSULPIRIDE+RABEPRAZOLE 1hour prior to food. Swallow LEVOSULPIRIDE+RABEPRAZOLE as a whole with a glass of water; do not chew or crush the tablet. Depending on your medical condition, your doctor will decide how long you need to take LEVOSULPIRIDE+RABEPRAZOLE.

Side Effects of Rebzed LS 75mg/20mg Capsule

• Headache
• Nausea
• Vomiting
• Flatulence
• Abdominal pain
• Dizziness
• Diarrhoea 

Similar Drugs

For informational purposes only. Consult a doctor before taking any medicines.

In-Depth Precautions and Warning

Drug Warnings

Do not take LEVOSULPIRIDE+RABEPRAZOLE if you are allergic to any of its contents. Inform your doctor before taking LEVOSULPIRIDE+RABEPRAZOLE if you have a history of pheochromocytoma (tumor of the adrenal gland), epilepsy, mania, gastrointestinal bleeding, intestinal obstruction, or severe kidney and liver impairment. LEVOSULPIRIDE+RABEPRAZOLE may cause osteoporosis (weak and brittle bones) and hypomagnesemia (low magnesium levels) on long-term treatment. Consult a doctor before taking LEVOSULPIRIDE+RABEPRAZOLE if you are pregnant or breastfeeding. LEVOSULPIRIDE+RABEPRAZOLE may cause dizziness and drowsiness, so drive only if you are alert. LEVOSULPIRIDE+RABEPRAZOLE is not recommended for children as safety and effectiveness have not been established. Avoid consuming alcohol along with LEVOSULPIRIDE+RABEPRAZOLE as it could lead to increased drowsiness and elevate stomach acid production.

Drug Interactions

Drug-Drug Interaction:

 LEVOSULPIRIDE+RABEPRAZOLE may have interaction with a blood thinner (warfarin), anti-cancer (methotrexate), cardiac glycoside (digoxin), immunosuppressant (mycophenolate mofetil, tacrolimus), antibiotic (amoxicillin, clarithromycin).

Drug-Disease Interaction:

 LEVOSULPIRIDE+RABEPRAZOLE may have interactions with gastrointestinal bleeding, intestinal obstruction, epilepsy, mania, Clostridium difficile-associated diarrhea (CDAD), hyperprolactinemia (high levels of prolactin), bone fractures, hypomagnesemia (low levels of magnesium).

Safety Advice

ALCOHOL

• Avoid consumption of alcohol while taking LEVOSULPIRIDE+RABEPRAZOLE. Alcohol intake leads to increased production of stomach acid, thereby increases acidity and heartburn.

PREGNANCY

• Consult your doctor before taking LEVOSULPIRIDE+RABEPRAZOLE if you are pregnant; your doctor will prescribe only if the benefits outweigh the risks.

BREAST FEEDING

• LEVOSULPIRIDE+RABEPRAZOLE may pass into breast milk. Consult your doctor before taking LEVOSULPIRIDE+RABEPRAZOLE; your doctor will decide whether LEVOSULPIRIDE+RABEPRAZOLE can be taken by breastfeeding mothers or not.

DRIVING

• LEVOSULPIRIDE+RABEPRAZOLE causes dizziness and drowsiness. Do not drive or operate machinery unless you are alert.

LIVER

• Dose adjustment may be needed. Consult your doctor before taking LEVOSULPIRIDE+RABEPRAZOLE if you have a liver impairment or any concerns regarding this.

KIDNEY

• Dose adjustment may be needed. Consult your doctor before taking LEVOSULPIRIDE+RABEPRAZOLE if you have kidney impairment or any concerns regarding this.