PRODUCT DETAILS

About Propyzole NF Cream

CLOBETASOL+CLOTRIMAZOLE belongs to the class of dermatological medication, primarily used to treat fungal skin infections. Fungal infection occurs when a fungus invades and affects the tissue on the skin. Fungi can live in the air, soil, water, and plants. Symptoms of a fungal infection include skin rash, irritation, redness, and scaling of the skin. 

CLOBETASOL+CLOTRIMAZOLE consists of two medicines, namely: Clobetasol (corticosteroid) and Clotrimazole (antifungal). Clobetasol is a highly potent corticosteroid with anti-inflammatory, antipruritic (relieves itching), and vasoconstrictive (narrows blood vessels) properties. It blocks the production of chemical mediators of inflammation (such as kinins, histamine, liposomal enzymes, and prostaglandins) that make the skin red, swollen, and itchy. On the other hand, Clotrimazole is an antifungal medication. It is used to treat various fungal infections, such as vaginal yeast infections, oral thrush, and ringworm. Clotrimazole stops the growth of fungi by causing damage and leakage to the fungal cell membrane. It is also used to treat athlete’s foot (fungal infection between the toes due to sweating) and jock itch (fungal infection in the skin of the genitals, inner thighs, and buttocks). 

CLOBETASOL+CLOTRIMAZOLE is available in the form of topical formulations like cream. Use this medication on the skin only as advised by the doctor. Common side effects of CLOBETASOL+CLOTRIMAZOLE are burning, irritation, itching, redness, and thinning of skin at the application site. These side effects do not require medical attention and gradually resolve over time. If these side effects persist longer, please consult your doctor. 

Avoid contact with your eyes, nose, or mouth while using CLOBETASOL+CLOTRIMAZOLE. Rinse it off with water thoroughly if you get the cream in these areas. Brief your medical history to the doctor, if you are allergic to CLOBETASOL+CLOTRIMAZOLE or any of its components. Therapy with topical corticosteroids like Clobetasol should be administered cautiously in patients with bacterial, fungal, viral, and protozoa infections. Let your doctor know if you have any medical history of liver, kidney diseases, glaucoma, cataract, poor blood circulation, immune system problems, diabetes, and adrenal gland diseases. Please consult your doctor if you are a pregnant or breastfeeding woman before using CLOBETASOL+CLOTRIMAZOLE.

Uses of Propyzole NF Cream

Fungal skin infections

Medicinal Benefits of Propyzole NF Cream

CLOBETASOL+CLOTRIMAZOLE treats fungal skin infections and is a combination of two medicines, namely: Clobetasol and Clotrimazole. Clobetasol is a highly potent corticosteroid with anti-inflammatory, antipruritic (relieves itching), and vasoconstrictive (narrows blood vessels) properties. It blocks the production of chemical mediators of inflammation that make the skin red, swollen, and itchy. It effectively treats inflammation and itching caused by plaque psoriasis (skin cells build up to form itchy scales and dry patches) and other skin conditions. Clotrimazole is an antifungal medication that treats fungal infections like vaginal yeast infections, oral thrush, and ringworm. It stops the growth of fungi by causing damage and leakage to the fungal cell membrane. It is also used to treat athlete’s foot (fungal infection between the toes due to sweating), jock itch (fungal infection in the skin of the genitals, inner thighs, and buttocks), and rash in folds of skin (intertrigo).

Directions for Use

CLOBETASOL+CLOTRIMAZOLE is available in the form of cream. Cream: Apply the cream onto clean, dry, unbroken skin affected by the infection. Apply it once or twice a day or as suggested. Do not use CLOBETASOL+CLOTRIMAZOLE on the face and avoid contact with the eyes, mouth, and nose. Do not put a bandage or a dressing on the affected area while using CLOBETASOL+CLOTRIMAZOLE unless advised by the doctor.

Side Effects of Propyzole NF Cream

• Burning 
• Irritation 
• Itching 
• Redness 
• Thinning of skin 

Similar Drugs

For informational purposes only. Consult a doctor before taking any medicines.

In-Depth Precautions and Warning

Drug Warnings

Brief your medical history to the doctor, if you are allergic to CLOBETASOL+CLOTRIMAZOLE or any of its components. Therapy with topical corticosteroids like Clobetasol should be administered cautiously in patients with bacterial, fungal, viral, and protozoa infections. Let your doctor know if you have any history of liver, kidney diseases, glaucoma, cataract, poor blood circulation, immune system problems, diabetes, and adrenal gland diseases. CLOBETASOL+CLOTRIMAZOLE is not recommended for diaper rash since it may be rapidly absorbed and can cause adrenal suppression, Cushing's syndrome (high cortisol levels), and intracranial hypertension (increased pressure around the brain) in infants.

CLOBETASOL+CLOTRIMAZOLE contains Clotrimazole that may cause abnormal test results like liver function tests, hence inform your doctor beforehand. Pregnant and breastfeeding women should use CLOBETASOL+CLOTRIMAZOLE with proper consultation and caution. Do not use CLOBETASOL+CLOTRIMAZOLE on the face and avoid contact with the eyes, nose, and throat. Rinse it off with water thoroughly if you get the cream in these areas. Do not put a bandage or a dressing on the affected area while using CLOBETASOL+CLOTRIMAZOLE unless advised by the doctor. Always wash hands before and after the application of CLOBETASOL+CLOTRIMAZOLE. Do not store CLOBETASOL+CLOTRIMAZOLE above 25°C.

Drug Interactions

Drug-Drug Interaction:

CLOBETASOL+CLOTRIMAZOLE may interact with other corticosteroids (prednisone), respiratory-related medicines (budesonide, formoterol), and drugs that lower the immune system (cyclosporine).

Drug-Disease Interaction:

CLOBETASOL+CLOTRIMAZOLE is contraindicated in fungal, viral, protozoa infections, liver, kidney diseases, glaucoma, cataract, poor blood circulation, immune system problems, diabetes, and adrenal gland diseases.

Safety Advice

ALCOHOL

No interaction was found of CLOBETASOL+CLOTRIMAZOLE with alcohol.

PREGNANCY

There is limited data on how the CLOBETASOL+CLOTRIMAZOLE affects pregnancy. CLOBETASOL+CLOTRIMAZOLE may be unsafe to use during pregnancy since it affects the baby. Please consult your doctor if you are planning to become pregnant or are already pregnant before starting CLOBETASOL+CLOTRIMAZOLE.

BREAST FEEDING

It is not known if CLOBETASOL+CLOTRIMAZOLE passes into the breast milk. Please consult your doctor before taking CLOBETASOL+CLOTRIMAZOLE if you are breastfeeding. If you need to apply the cream or ointment on your breasts, don't do this shortly before giving a feed.

DRIVING

There have been no studies to investigate the effect of CLOBETASOL+CLOTRIMAZOLE on driving performance or the ability to operate machinery.

LIVER

Let your doctor know if you have any history of liver diseases before taking CLOBETASOL+CLOTRIMAZOLE.

KIDNEY

Let your doctor know if you have any history of kidney diseases before taking CLOBETASOL+CLOTRIMAZOLE.