PRODUCT DETAILS

About Ibupil Plus 400 mg/500 mg Tablet

IBUPROFEN+PARACETAMOL belongs to a class of painkillers called as non-steroidal anti-inflammatory drugs (NSAIDs). It relieves symptoms of muscle pain, arthritis pain, dysmenorrhea (painful periods or menstrual cramps), dental pain and reduces fever. Pain can be temporary (acute) or long-lasting (chronic) in nature. Acute pain is for a short time caused by damage to the tissues of the muscle, bone, or other organs. While, chronic pain lasts for a long duration and is  caused due to pathologies like nerve damage, osteoarthritis etc. Besides this it is also useful for dental pain which can occur due to damage to the tooth nerve, infection, decay, extraction or injury.

Uses of Ibupil Plus 400 mg/500 mg Tablet

Muscle pain, Arthritis pain, Headache, Migraine, Backache, Dental pain, Fever

Medicinal Benefits of Ibupil Plus 400 mg/500 mg Tablet

IBUPROFEN+PARACETAMOL is composed of Ibuprofen and Paracetamol primarily used to treat mild to moderate pain. IBUPROFEN+PARACETAMOL is prescribed mainly to treat pain and get relief from discomfort cause in conditions like tooth pain, arthritis, period pain and other type of short term pains. It helps in treating pain by blocking the chemical messenger (prostaglandin) in the brain responsible for causing pain. Ibuprofen works by blocking the effect of a chemical known as prostaglandin responsible for inducing pain and inflammation in our body. On the other hand, Paracetamol lowers the elevated body temperature and mild pain by inhibiting the synthesis of prostaglandin by promoting heat loss (through sweating) that helps reset the hypothalamic thermostat. Paracetamol has got the advantage of producing less gastric irritation compared to other painkillers like aspirin.

Directions for Use

Take it with food or milk to avoid upsetting of the stomach. Do not chew, crush or break the tablet.

Side Effects of Ibupil Plus 400 mg/500 mg Tablet

Most of the side effects of IBUPROFEN+PARACETAMOL do not require medical attention and gradually resolve over time. The most common side effect of IBUPROFEN+PARACETAMOL are thrombocytopenia (low level of platelets), neutropenia/leucopenia (low white blood cells), skin rashes (urticaria), peptic ulcers, gastrointestinal bleeding, nausea, vomiting, diarrhea, flatulence, constipation, dyspepsia, abdominal pain, colitis (inflammation of the intestine) and Crohn's disease (inflammatory bowel disorder). These side effects are for a short time interval. However, if these side effects persist reach out to the doctor.

Similar Drugs

For informational purposes only. Consult a doctor before taking any medicines.

In-Depth Precautions and Warning

Drug Warnings

Caution is advised in people with underlying sensitivity to aspirin and other pain killers. IBUPROFEN+PARACETAMOL is contraindicated in children below 12 years of age under 40 kg of weight. If treatment is required for more than 3 days consult your doctor. IBUPROFEN+PARACETAMOL should be taken with caution if you have an allergy to paracetamol, ibuprofen, aspirin, or other pain killers, highly sensitive reactions (asthma, lip/face/throat swelling), existing stomach ulcer or bleeding associated pain killers, blood clotting disorder, heart diseases (like congestive heart failure), kidney disease, peptic ulcer, other active bleeding (like brain stroke bleeding), and severe dehydration (due to vomiting, diarrhoea). Liver damage might occur if taken for a longer duration as it contains paracetamol. The skin should be closely monitored as skin allergic reactions like Stevens-Johnson syndrome (SJS), and toxic epidermal necrolysis (TEN) have been reported with the use of IBUPROFEN+PARACETAMOL. Blood pressure and cardiovascular (heart) status should be monitored closely during the treatment with IBUPROFEN+PARACETAMOL especially in people affected with high blood pressure and who had a history of heart failure.

Drug Interactions

Drug-Drug Interaction:

IBUPROFEN+PARACETAMOL is shown to interact with various drugs. Some of them includes lithium, blood thinner or anticoagulant (warfarin, ticlopidine), anti-arthritis pills (methotrexate), blood pressure or heart medicine, nausea/vomiting medicine (metoclopramide, domperidone), diuretic/water pills (thiazides, furosemide), steroid medicine (prednisone), quinolones antibiotics (ciprofloxacin), respiratory medicines (theophylline, ephedrine), cholesterol reducing medicine (colestyramine) and antidepressants (duloxetine). These drugs may affect the working of IBUPROFEN+PARACETAMOL and may alter its efficacy.

Drug-Disease Interaction:

 IBUPROFEN+PARACETAMOL should not recommend for people having liver disease (like Gilbert’s syndrome in which liver does not process bile), asthma, skin allergic diseases (Stevens-Johnson syndrome, toxic epidermal necrolysis), blood clot disorder, high blood pressure (hypertension), or history of heart failure. Besides this, IBUPROFEN+PARACETAMOL should not be given to the children suffering with influenza (flu) or chickenpox. It should also be avoided in case of presence of gastric/duodenal ulcers and low glutathione level.

Safety Advice

ALCOHOL

Taking IBUPROFEN+PARACETAMOL with alcohol may cause dizziness or drowsiness. Besides this, it can also damage your liver if taken for a longer duration. So, avoid or limit intake of alcoholic beverages with IBUPROFEN+PARACETAMOL.

PREGNANCY

Use of IBUPROFEN+PARACETAMOL during pregnancy is not recommended as taking this medicine during the last 3 months of pregnancy may harm the unborn baby.

BREAST FEEDING

Take IBUPROFEN+PARACETAMOL only if prescribed by your doctor.

DRIVING

After taking IBUPROFEN+PARACETAMOL you may notice dizziness, sleepiness, drowsiness or fatigue as it contain paracetamol which causes sedation. So, in this you should stop taking IBUPROFEN+PARACETAMOL and contact your doctor.

LIVER

IBUPROFEN+PARACETAMOL to be taken with caution, especially if you have a history of liver disease. Dose may have to be adjusted by your doctor.

KIDNEY

IBUPROFEN+PARACETAMOL to be taken with caution, especially if you have a history of Kidney diseases/conditions. Dose may have to be adjusted by your doctor.