PRODUCT DETAILS

About Derbo Eye Drop

TOBRAMYCIN+DEXAMETHASONE is a combination of antibiotics and corticosteroids, primarily used to treat eye infections such as conjunctivitis (pink eye). Conjunctivitis is the infection of the outer white membrane of the eyeball. This infection is highly contagious in nature and can pass from one to another. Signs and symptoms include pink/red-toned eyes, gritty feeling in eyes, itchiness in areas of eyes, teary eyes, and thick discharge around eyes. 

TOBRAMYCIN+DEXAMETHASONE is a combination of two drugs, namely; Tobramycin and Dexamethasone. Tobramycin is an aminoglycoside that inhibits bacteria growth by interfering with protein synthesis. It binds to the bacteria's proteins, disrupting the cell membrane, and eventually leading to cell death. Dexamethasone is a corticosteroid that reduces swelling and redness by preventing infection-fighting white blood cells (WBCs) from traveling to the area of swelling in your body.

TOBRAMYCIN+DEXAMETHASONE should be taken in the dose and duration as advised by your doctor. You are advised to take TOBRAMYCIN+DEXAMETHASONE for as long as your doctor has prescribed it for you depending on your medical condition. TOBRAMYCIN+DEXAMETHASONE can cause some common side effects (when eye drops are used) including redness, itching, swelling, burning sensation, tearing, and temporary blurred vision (with ointment use). Most of these side effects of TOBRAMYCIN+DEXAMETHASONE do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor. Long-term use of eye drops may cause a fungal eye infection. So, take this medicine for a duration prescribed by your doctor.

Inform your doctor if you are allergic to TOBRAMYCIN+DEXAMETHASONE, other aminoglycoside antibiotics, or any other ingredients present in it. Inform your doctor if you are using topical nonsteroidal anti-inflammatory drugs. If you use topical nonsteroidal anti-inflammatory drugs and TOBRAMYCIN+DEXAMETHASONE together, it may delay the healing of your eye wound. Contact lens wear is not recommended during the treatment of ocular infection or inflammation. Tell your doctor if you have myasthenia gravis (muscle disorders), Parkinson’s disease (a brain disorder), and kidney problems. Inform your doctor if you have any vision problems after using this medication. Tell your doctor if you are pregnant or breastfeeding. 

Uses of Derbo Eye Drop

Bacterial conjunctivitis 

Medicinal Benefits of Derbo Eye Drop

TOBRAMYCIN+DEXAMETHASONE is a combination of two drugs: Tobramycin (antibiotics) and Dexamethasone (corticosteroids). Tobramycin belongs to a group of antibiotics called aminoglycosides that works by stopping the growth of bacteria. It reduces the infection by inhibiting bacterial growth. It irreversibly binds to a site on the bacterial ribosomes (ribosomes are responsible for protein synthesis), inhibiting protein formation. Proteins are essential for bacterial growth. So, if bacteria cannot make proteins, they will eventually die. Dexamethasone is a corticosteroid that blocks chemical messenger in the brain responsible for causing inflammation (redness, itching, and swelling). As a result, it lowers inflammation, which could otherwise make the condition worse. TOBRAMYCIN+DEXAMETHASONE is used to prevent and treat inflammation and prevent possible bacterial infection of the eye after cataract surgery in adults and children above 2 years of age. 

Directions for Use

Eye drops: Wash your hands thoroughly with water before and after use. Tilt your head back and pull down the lower eyelid to create a small sac. Take the prescribed amount of dose with the dropper and squeeze out a drop. Close your eyes for about 2 to 3 minutes. Wipe any excess liquid with a tissue. Do not wipe or rinse the dropper tip after use. Place the dropper back on the bottle and tighten the cap. Eye ointment: Eye ointment is also used similarly. Create a pocket pulling the lower eyelid while tilting your head back. Then, squeeze out a prescribed amount of ointment and close your eyes. You may experience blurred vision for some time after opening your eyes. So, rest for a while before doing anything.

Side Effects of Derbo Eye Drop

• Eye redness
• Burring sensation

Similar Drugs

For informational purposes only. Consult a doctor before taking any medicines.

In-Depth Precautions and Warning

Drug Warnings

If you are allergic to TOBRAMYCIN+DEXAMETHASONE or any other medicines, please tell your doctor. Consult your doctor before taking TOBRAMYCIN+DEXAMETHASONE if you are pregnant or breastfeeding. TOBRAMYCIN+DEXAMETHASONE is not recommended for children unless prescribed by a doctor. Let your doctor know, that if you have had myasthenia gravis (muscle weakness) or Parkinson’s disease, antibiotics like tobramycin may worsen muscle weakness. You are advised to remove soft contact lenses before using TOBRAMYCIN+DEXAMETHASONE as it contains a preservative that may cause eye irritation and discoloration of soft contact lenses. You can reinsert contact lenses after 15 minutes of using TOBRAMYCIN+DEXAMETHASONE. Do not use the topical non-steroidal inflammatory drug while using TOBRAMYCIN+DEXAMETHASONE. TOBRAMYCIN+DEXAMETHASONE contains dexamethasone; if you use topical non-steroidal inflammatory drug and dexamethasone together, it may delay the healing of your eye wound. If you have diabetes, please consult your doctor before using TOBRAMYCIN+DEXAMETHASONE. The risk of intraocular pressure (glaucoma) and cataract formation is increased in diabetic patients. TOBRAMYCIN+DEXAMETHASONE may cause temporary vision problems (blurred vision), so be cautious while driving and operating machinery. 

Drug Interactions

Drug-Drug Interaction:

TOBRAMYCIN+DEXAMETHASONE may interact with other antibiotics (vancomycin, gentamicin, kanamycin, streptomycin, cephalothin), pain relievers (diclofenac, bromfenac) antiviral (ritonavir, cobicistat, boceprevir, amprenavir, atazanavir),  antifungal (itraconazole, ketoconazole, miconazole, posaconazole, voriconazole), antidiabetics (metformin, canagliflozin, glimepiride, pioglitazone), smallpox vaccine.

Drug-Disease Interaction:

TOBRAMYCIN+DEXAMETHASONE should be used with caution in patients with a corneal transplant, diabetes, myasthenia gravis, and Parkinson's disease.

Safety Advice

ALCOHOL

The interaction of TOBRAMYCIN+DEXAMETHASONE with alcohol is unknown. Please consult a doctor before consuming alcohol while using TOBRAMYCIN+DEXAMETHASONE.

PREGNANCY

Please consult a doctor if you are pregnant. TOBRAMYCIN+DEXAMETHASONE is given to pregnant women only if the doctor thinks the benefits outweigh the risks.

BREAST FEEDING

TOBRAMYCIN+DEXAMETHASONE is given to breastfeeding mothers only if the doctor thinks the benefits are greater than the risks.

DRIVING

Drive with caution, TOBRAMYCIN+DEXAMETHASONE usually causes temporarily blurred vision and affects driving ability.

LIVER

TOBRAMYCIN+DEXAMETHASONE is safe to use in patients with liver disease only when prescribed by a doctor.

KIDNEY

TOBRAMYCIN+DEXAMETHASONE is safe to use in patients with kidney disease only when prescribed by a doctor.