PRODUCT DETAILS

About Skizoril MD 50 Tablet

CLOZAPINE belongs to a group of medicines called antipsychotics used to treat schizophrenia. Additionally, CLOZAPINE is also used to reduce the risk of suicidal behavior in patients with schizophrenia or other similar disorders. Schizophrenia is a medical condition in which the person may feel, hear or see things that are not there, believe things that are not true, or feel unusually suspicious or confused.

CLOZAPINE contains ‘Clozapine’ that works by blocking the effects of chemical receptors in the brain such as dopamine and serotonin, thereby helping in improving mood, behavior, and thoughts.

Take CLOZAPINE with or without food. Swallow CLOZAPINE as a whole with a glass of water, do not chew or crush the tablet. You are advised to take CLOZAPINE for as long as your doctor has prescribed it for you depending on your medical condition. In some cases, you may experience certain common side effects such as tachycardia (fast heartbeat), dizziness, headache, tremor, sweating, dry mouth, nausea, constipation, and visual disturbances. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Please do not stop taking CLOZAPINE suddenly as it might cause withdrawal symptoms. Consult your doctor before taking CLOZAPINE if you are pregnant. Do not take CLOZAPINE if you are breastfeeding as it may pass into breastmilk. CLOZAPINE causes drowsiness and dizziness, do not drive unless you are alert. CLOZAPINE should not be given to children as safety and effectiveness have not been established. Avoid consuming alcohol along with CLOZAPINE as it could lead to increased drowsiness and dizziness. Keep your doctor informed about your health condition and medicines to rule out any side effects.

Uses of Skizoril MD 50 Tablet

Schizophrenia

Medicinal Benefits of Skizoril MD 50 Tablet

CLOZAPINE belongs to a group of medicines called antipsychotics. CLOZAPINE is used to treat schizophrenia and to reduce the risk of suicidal behavior in patients with schizophrenia or other similar disorders. CLOZAPINE works by blocking the effects of chemical receptors in the brain such as dopamine and serotonin, thereby helping in improving mood, behavior, and thoughts. CLOZAPINE is used to treat schizophrenia when two or other antipsychotic drugs were not effective or have caused severe adverse effects. CLOZAPINE is also used to treat psychotic disorders in patients with Parkinson’s disease when standard treatments have failed.

Directions for Use

Take CLOZAPINE with or without food. Swallow CLOZAPINE as a whole with a glass of water, do not chew or crush the tablet. Based on your medical condition, your doctor will decide how long you need to take CLOZAPINE.

Side Effects of Skizoril MD 50 Tablet

• Tachycardia (fast heartbeat)
• Dizziness
• Headache
• Tremor
• Sweating
• Low blood pressure
• Dry mouth
• Nausea
• Constipation
• Visual disturbances

Similar Drugs

For informational purposes only. Consult a doctor before taking any medicines.

In-Depth Precautions and Warning

Drug Warnings

Do not take CLOZAPINE if you are allergic to any of its contents if you have galactose intolerance, total lactase deficiency, glucose-galactose malabsorption, low number of white blood cells, or taking medicines that can cause low levels of white blood cells, bone marrow disorder, epilepsy, circulatory collapse (pronounced fall in blood pressure that can lead to unconsciousness), brain disorders, severe kidney disease, heart disease, liver disease with jaundice, liver failure or paralytic ileus (small intestine disorder). Inform your doctor if you have a low number of white blood cells or platelet count, orthostatic hypotension, epilepsy, enlarged prostate or difficulty urinating, glaucoma, severe constipation, diabetes, heart, liver, or kidney problems. Consult your doctor before taking CLOZAPINE if you are pregnant. Do not take CLOZAPINE if you are breastfeeding as it may pass into breastmilk. CLOZAPINE causes drowsiness and dizziness, do not drive unless you are alert. CLOZAPINE should not be given to children as safety and effectiveness have not been established. Avoid consuming alcohol along with CLOZAPINE as it could lead to increased drowsiness and dizziness. Be careful while taking CLOZAPINE along with antihistamines (medicines used to treat colds, allergies, or hay fever), together they might cause increased drowsiness.  CLOZAPINE might affect how your body controls temperature, therefore being cautious while exercising, taking hot baths, or sauna, as CLOZAPINE might make you dizzy or faint.

Drug Interactions

Drug-Drug Interaction:

CLOZAPINE may have interaction with antipsychotic (aripiprazole, haloperidol, lurasidone, lithium, risperidone, quetiapine, olanzapine), anti-anxiety (lorazepam, alprazolam), anti-cholinergic (benztropine), anti-depressant (duloxetine, escitalopram, sertraline), anti-convulsant (divalproex sodium, clonazepam, lamotrigine),  muscle relaxants (carisoprodol, cyclobenzaprine),  antihistamines (cetirizine, diphenhydramine).

Drug-Disease Interaction:

 CLOZAPINE may have interactions with dementia (memory loss), CNS depression, liver disease, seizures, low blood pressure, diabetes, lipid alterations, weight gain, parkinsonism, acute alcohol intoxication, Neuroleptic malignant syndrome (which occurs due to reaction with antipsychotic drugs), Tardive dyskinesia (repetitive, involuntary movements), QT interval prolongation, kidney impairment/disease, blood abnormalities, lipid alterations and Hyperprolactinemia (higher levels of prolactin in the blood).

Safety Advice

ALCOHOL

Avoid consumption of alcohol while taking CLOZAPINE as it may cause increased drowsiness.

PREGNANCY

CLOZAPINE belongs to pregnancy category B. Please consult your doctor if you have any concerns regarding this, your doctor will prescribe only if the benefits outweigh the risks.

BREAST FEEDING

CLOZAPINE is not recommended during breastfeeding.

DRIVING

CLOZAPINE causes tiredness, dizziness, and vision problems. Do not drive or operate machinery if you experience these symptoms.

LIVER

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

KIDNEY

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.