PRODUCT DETAILS

About Pramirise 0.75mg Tablet

PRAMIPEXOLE belongs to a group of antiparkinson agents or dopamine agonists used to treat the symptoms of Parkinson’s disease and moderate to severe Willis-Ekbom disease (restless legs syndrome) in adults. Parkinson’s disease is a progressive neurological disorder in which the first signs are problems with movements. Willis-Ekbom disease is a condition which causes the uncontrollable urge to move the legs.

PRAMIPEXOLE contains 'Pramipexole' that works by mimicking the action of dopamine (acting in place of dopamine), which is a natural substance found in the brain needed to control body movement. This triggers the nerve impulses in the brain that control the body movements.

Uses of Pramirise 0.75mg Tablet

Parkinson’s disease, Willis Ekbom disease (restless legs syndrome)

Medicinal Benefits of Pramirise 0.75mg Tablet

PRAMIPEXOLE belongs to a group of antiparkinson agents called dopamine agonists used to treat the symptoms of Parkinson’s disease and moderate to severe Willis-Ekbom disease (restless legs syndrome) in adults. PRAMIPEXOLE binds to the dopamine receptor and mimics its action. Dopamine is a naturally-occurring neurotransmitter in the brain. Dopamine is absent or reduced in people with Parkinson’s disease. PRAMIPEXOLE works by stimulating the dopamine receptors in the brain. This triggers the nerve impulses in the brain that control the body movements. PRAMIPEXOLE helps in relieving the symptoms of Parkinson’s disease, such as muscle spasms, tremors, stiffness, and poor muscle control.

Directions for Use

Take PRAMIPEXOLE with or without food. Take PRAMIPEXOLE exactly as prescribed by the doctor. PRAMIPEXOLE should be swallowed as a whole with a glass of water; do not chew, or crush the tablet. For restless leg syndrome, PRAMIPEXOLE should be taken 2-3 hours before bedtime. Based on your medical condition, your doctor will decide how long you need to take PRAMIPEXOLE.

Side Effects of Pramirise 0.75mg Tablet

Like all medicines, PRAMIPEXOLE can also cause side-effects, although not everybody experiences them. Nausea, low blood pressure, dizziness, constipation, fatigue, headache, dry mouth, muscle spasms, dyskinesia (a movement disorder), sleepiness, insomnia, and peripheral oedema (swelling of lower legs and hands) are the common side-effects of PRAMIPEXOLE. Please consult your doctor if you experience any of these side-effects persistently.

Similar Drugs

For informational purposes only. Consult a doctor before taking any medicines.

In-Depth Precautions and Warning

Drug Warnings

Do not take PRAMIPEXOLE if you are allergic to any of its contents. Talk to your doctor before taking PRAMIPEXOLE if you have kidney problems, hallucinations, dyskinesia (abnormal limb movements), dystonia (inability to keep the neck straight), sleepiness or suddenly falling asleep, psychosis, vision impairment, severe heart or blood vessel disease, or augmentation (symptoms start earlier). Inform your doctor if you experience symptoms such as apathy, anxiety, depression, fatigue, sweating or pain after dose reduction or stopping PRAMIPEXOLE. PRAMIPEXOLE may cause intense urges such as increased sex drive, gambling, overeating and wasting money. Do not take PRAMIPEXOLE if you are pregnant or breastfeeding unless prescribed by the doctor. PRAMIPEXOLE causes drowsiness and dizziness, do not drive unless you are alert. PRAMIPEXOLE should not be given to children below 18 years. Avoid consuming alcohol along with PRAMIPEXOLE as it could lead to increased drowsiness and dizziness. Rise slowly from sitting or lying position as PRAMIPEXOLE causes orthostatic hypotension (sudden lowering in blood pressure leading to dizziness on standing). 

Drug Interactions

Drug-Drug Interaction:

PRAMIPEXOLE may have interaction with anti-depressants (amitriptyline, duloxetine, trazodone, and fluoxetine), antihistamine (diphenhydramine, and cetirizine), anticonvulsants (gabapentin, and pregabalin), a drug used to treat Alzheimer’s (memantine), and pain killers (acetaminophen, hydrocodone, and tramadol).

Drug-Disease Interaction:

 PRAMIPEXOLE may have interactions with disease conditions such as low blood pressure, neuroleptic malignant syndrome, psychosis, and renal function disorders.

Safety Advice

ALCOHOL

Avoid consumption of alcohol while taking PRAMIPEXOLE as it may cause increased dizziness.

PREGNANCY

Avoid taking PRAMIPEXOLE if you are pregnant unless prescribed by a doctor. Please consult your doctor if you have any concerns regarding this, your doctor will prescribe only if the benefits outweigh the risks.

BREAST FEEDING

Do not take PRAMIPEXOLE if you are breastfeeding. PRAMIPEXOLE may reduce the production of breast milk. Also, it can pass into breast milk. If taking PRAMIPEXOLE is unavoidable, stop breastfeeding.

DRIVING

PRAMIPEXOLE causes dizziness, sleepiness and hallucinations. Avoid driving and handling machinery if you experience these symptoms.

LIVER

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

KIDNEY

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.