PRODUCT DETAILS

About Pefroxim 1500mg Injection

CEFUROXIME belongs to the class of antibiotics known as cephalosporin, indicated for treating a wide range of bacterial infections. It helps in the treatment of urinary tract infections (UTI), Mild to moderate lower respiratory tract infections (bronchitis), severe lower respiratory tract infections (pneumonia), pyelonephritis (kidney inflammation due to the bacterial infection), uncomplicated gonorrhoea (sexually transmitted infection), Lyme disease (caused due to biting of infected black-legged tick insect) in adults and children above 12 years of age.

CEFUROXIME is a broad-spectrum antibiotic that kills a wide range of bacteria (bactericidal). It kills the bacterial cell by binding to the outer layer of the bacteria and blocking the activity of the enzyme that makes peptidoglycan (a vital component of the bacterial cell wall). As a result, the bacterial cell cannot grow and multiply and finally gets killed.

Uses of Pefroxim 1500mg Injection

Bacterial infections

Medicinal Benefits of Pefroxim 1500mg Injection

CEFUROXIME treats a wide range of bacterial infections caused due to gram-positive and gram-negative bacteria. It helps treat respiratory tract infections, ear infections, skin infections, genitourinary infections, and bone infections. Besides this, CEFUROXIME also prevents in spreading of the infection after surgery and in the early treatment of Lyme disease caused by bacteria (Borrelia burgdorferi) in adults and children over the age of 12 years. The usual course of CEFUROXIME is seven days (5-10 days). But, your doctor might prescribe you CEFUROXIME for a longer duration depending on the condition of infection. CEFUROXIME has excellent antibacterial activity against gram-positive and gram-negative bacteria, including Staphylococcus aureus, Haemophilus para influenza, Streptococcus pneumonia, S. pyrogens, Haemophilus influenzae, Klebsiella pneumoniae, Moraxella catarrhalis, and Neisseria gonorrhoeae.

Directions for Use

Tablet: Swallow it as a whole with water; do not crush, break or chew it. Suspension/Syrup: Shake the bottle well before use. Check the label for directions and take CEFUROXIME in doses as prescribed by your doctor with the help of a measuring cup. Dispersible Tablet: Check the label for directions before use. Disperse the tablet in the prescribed amount of water and swallow the whole contents.

Side Effects of Pefroxim 1500mg Injection

• Headache
• Dizziness
• Stomach upset
• Overgrowth of candida (fungal skin infection)
• Unpleasant taste in the mouth
• Diaper rashes
• Eosinophilia (increased disease-fighting cells/WBC) 

Similar Drugs

For informational purposes only. Consult a doctor before taking any medicines.

In-Depth Precautions and Warning

Drug Warnings

Special care should be taken by the people taking CEFUROXIME who have allergic reactions to penicillin or other beta-lactam antibiotics. Use with other antibiotics may lead to a fungal skin infection known as Candida. Prolonged use of CEFUROXIME may also cause an overgrowth of other pathogens (like enterococci and Clostridium difficile), which can be prevented by stopping CEFUROXIME. The case of colitis (inflammatory bowel disease) has been reported using CEFUROXIME. Hence, it is important to consider the proper diagnosis of the patients who developed diarrhoea after taking CEFUROXIME. If the symptom of diarrhoea persists for a longer duration, the patient may experience abdominal cramps. In this situation, you should discontinue the intake of CEFUROXIME immediately. The Jarisch-Herxheimer reaction (caused due to toxins released by the death of bacteria within the body during antibiotic treatment) has been seen in the patients taking CEFUROXIME for the treatment of Lyme disease. Your ability to perform tasks that require judgment, cognitive, or body movement may be affected, and you may have dizziness. So patients taking CEFUROXIME should be warned to be cautious when driving or operating machinery.

Drug-Drug Interaction:

You should avoid taking CEFUROXIME with oral birth control pills, medicines that reduce gastric acidity (like antacids, omeprazole), immuno-suppressing drugs (mycophenolate or mycophenolic acid), medicines used for reducing uric acid (probenecid), and some urine glucose tests. Besides this, it also interacts with typhoid and BCG vaccines.