PRODUCT DETAILS

About Koxilex-TH Tablet

ETORICOXIB+THIOCOLCHICOSIDE belongs to a group of medicines called Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) used for the treatment of osteoarthritis, rheumatoid arthritis, gouty arthritis, and ankylosing spondylitis, acute pain, chronic low back pain, and muscle spasms. Pain is a symptom triggered by the nervous system, causing uncomfortable sensations in the body. Muscle spasm is the sudden involuntary contractions of the muscle, which can be painful and uncomfortable.

ETORICOXIB+THIOCOLCHICOSIDE is a combination of two drugs: Etoricoxib (NSAID) and Thiocolchicoside (Muscle relaxant). Etoricoxib blocks the effect of a chemical messenger known as cyclo-oxygenase (COX) enzyme that makes other chemical prostaglandins (PG). By blocking the effect of COX enzymes, lesser PGs are produced. This helps in reducing mild to moderate pain and inflammation at the injured or damaged site. Thiocolchicoside works on the centers of the spinal cord and brain. This helps relieve muscle stiffness and improves muscle movements, thereby helping relieve pain due to muscle spasms.

You can take ETORICOXIB+THIOCOLCHICOSIDE with or without food. Swallow ETORICOXIB+THIOCOLCHICOSIDE as a whole with water, do not crush or chew the tablet. You are advised to take ETORICOXIB+THIOCOLCHICOSIDE for as long as your doctor has prescribed it for you depending on your medical condition. In some cases, you may experience certain common side effects such as flatulence, nausea, diarrhea, indigestion, and swelling of your hands and feet. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

ETORICOXIB+THIOCOLCHICOSIDE can increase your risk of fatal heart attack or stroke. So, if you have had any recent heart surgery, do not take ETORICOXIB+THIOCOLCHICOSIDE. ETORICOXIB+THIOCOLCHICOSIDE increases the chances of stomach ulcers and bleeding. Do not take ETORICOXIB+THIOCOLCHICOSIDE if you are pregnant or breastfeeding unless prescribed by the doctor. ETORICOXIB+THIOCOLCHICOSIDE may cause sleepiness and dizziness, so drive with caution. ETORICOXIB+THIOCOLCHICOSIDE should not be given to children as safety and efficacy have not been established. Avoid consuming alcohol along with ETORICOXIB+THIOCOLCHICOSIDE as it could lead to increased dizziness, it might also increase the risk of stomach bleeding. Keep your doctor informed about your health condition and medicines to rule out any side effects.

Uses of Koxilex-TH Tablet

Pain, inflammation, and muscle spasms

Medicinal Benefits of Koxilex-TH Tablet

ETORICOXIB+THIOCOLCHICOSIDE is a combination of two drugs: Etoricoxib (Non-Steroidal Anti-Inflammatory Drugs) and Thiocolchicoside (Muscle relaxant). ETORICOXIB+THIOCOLCHICOSIDE is used for the treatment of osteoarthritis, rheumatoid arthritis, gout and ankylosing spondylitis, acute pain, chronic low back pain, and muscle spasms. Etoricoxib blocks the effect of a chemical messenger known as cyclo-oxygenase (COX) enzyme that makes another chemical 'prostaglandins' (PG). These prostaglandins are produced at injury sites and cause pain and swelling. By blocking the effect of COX enzymes, lesser PGs are produced. This helps in reducing mild to moderate pain and inflammation at the injured or damaged site. Thiocolchicoside works on the centers of the spinal cord and brain. This helps relieve muscle stiffness and improves muscle movements, thereby helping relieve pain due to muscle spasms.

Directions for Use

Take ETORICOXIB+THIOCOLCHICOSIDE with or after food. Swallow ETORICOXIB+THIOCOLCHICOSIDE as a whole with a glass of water, do not chew or break the tablet. Based on your medical condition, your doctor will decide how long you need to take ETORICOXIB+THIOCOLCHICOSIDE.

Side Effects of Koxilex-TH Tablet

• Flatulence
• Indigestion
• Stomach pain
• Nausea
• Diarrhea
• Swelling of hands and feet
• Irregular heartbeat

Similar Drugs

For informational purposes only. Consult a doctor before taking any medicines.

In-Depth Precautions and Warning

Drug Warnings

Do not take ETORICOXIB+THIOCOLCHICOSIDE if you are allergic to any of its contents, if you have stomach ulcers, have suffered bleeding problems, clotting problems, inflammatory bowel disease, severe heart, liver or kidney problems, galactose intolerance, Lapp lactase deficiency or glucose-galactose malabsorption. ETORICOXIB+THIOCOLCHICOSIDE can increase your risk of fatal heart attack or stroke. So, if you have had any recent heart surgery, do not take ETORICOXIB+THIOCOLCHICOSIDE. Inform your doctor before taking ETORICOXIB+THIOCOLCHICOSIDE if you have had stomach bleeding or ulcers, heart failure, high blood pressure, diabetes, high cholesterol, or kidney or liver impairment. Do not take ETORICOXIB+THIOCOLCHICOSIDE if you are pregnant or breastfeeding unless prescribed by the doctor. ETORICOXIB+THIOCOLCHICOSIDE may cause sleepiness and dizziness, so drive only if you are alert. ETORICOXIB+THIOCOLCHICOSIDE should not be given to children as safety has not been established. Avoid consuming alcohol along with ETORICOXIB+THIOCOLCHICOSIDE as it could lead to increased drowsiness and can increase the risk of stomach bleeding. Stop taking ETORICOXIB+THIOCOLCHICOSIDE and consult your doctor immediately if you have stomach pain or any signs of bleeding in the intestine or stomach such as blood in stools. Do not take any other NSAIDs for pain relief along with ETORICOXIB+THIOCOLCHICOSIDE unless prescribed.

Drug Interactions

Drug-Drug Interaction:

ETORICOXIB+THIOCOLCHICOSIDE may have interaction with pain killers (aspirin), bronchodilators (salbutamol), anti-depressants (lithium), cardiac glycoside (digoxin), anti-hypertensives (enalapril, ramipril, losartan, valsartan, minoxidil), antibiotics (rifampicin), blood thinners (warfarin), immunosuppressants (cyclosporine, tacrolimus), and anti-rheumatoid (methotrexate).

Drug-Disease Interaction:

ETORICOXIB+THIOCOLCHICOSIDE may have interactions with stomach ulcers, blood disorders, stomach disorders, diabetes, high blood pressure, high cholesterol, galactose intolerance, Lapp lactase deficiency, or glucose-galactose malabsorption, heart, kidney, and liver problems.

Safety Advice

ALCOHOL

Avoid consumption of alcohol while taking ETORICOXIB+THIOCOLCHICOSIDE as it may increase drowsiness. It can also increase the risk of stomach bleeding.

PREGNANCY

Please consult your doctor if you have any concerns regarding this, your doctor will prescribe only if the benefits outweigh the risks.

BREAST FEEDING

Please consult your doctor before taking ETORICOXIB+THIOCOLCHICOSIDE; your doctor will decide whether ETORICOXIB+THIOCOLCHICOSIDE can be taken by breastfeeding mothers or not.

DRIVING

ETORICOXIB+THIOCOLCHICOSIDE may cause dizziness and sleepiness. Do not drive or operate machinery unless you are alert.

LIVER

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

KIDNEY

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.