PRODUCT DETAILS

About Klomin 50mg Tablet

CLOMIPRAMINE belongs to a class of drugs called 'antidepressants' used to treat obsessive-compulsive disorder (OCD), depression, panic and anxiety disorder. OCD is a mental disorder with symptoms such as excessive thoughts or ideas (obsessions), leading to repetitive behaviours (compulsions). Depression is a mood disorder associated with symptoms such as sadness, unable to sleep properly or enjoying life as you used to do. Panic or anxiety disorder is linked to anxiety with sudden feelings of unnecessary fear or worries even when there is no danger in reality.

CLOMIPRAMINE contains Clomipramine that works by increasing the activity of serotonin and noradrenaline (chemical messengers) in the brain involved in regulating mood, behaviour and emotions. Thereby, CLOMIPRAMINE helps relieve depression, lighten the mood and relieve anxiety symptoms such as fear and panic.

Take CLOMIPRAMINE with food as prescribed by your doctor and swallow it whole with a glass of water. Do not break, crush or chew it. Your doctor will advise you on how often you take CLOMIPRAMINE based on your medical condition. Some people may experience dizziness, headache, drowsiness, dry mouth, nausea, weight gain, increased sweating, constipation, shaking, blurred vision, erectile dysfunction or difficulty in urination. Most of these side effects of CLOMIPRAMINE do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to CLOMIPRAMINE or any other medicines, please tell your doctor. CLOMIPRAMINE is not recommended for children below 17 years of age. Avoid taking CLOMIPRAMINE if you are pregnant as it may cause harm to the foetus. Avoid breastfeeding while taking CLOMIPRAMINE as it may be excreted in human milk and cause adverse effects in the baby. If you have any self-harming or suicidal thoughts before taking CLOMIPRAMINE, inform your doctor as they may worsen in the initial days of taking CLOMIPRAMINE.

Uses of Klomin 50mg Tablet

Obsessive-compulsive disorder (OCD), Depression, Panic disorder, Anxiety disorder

Medicinal Benefits of Klomin 50mg Tablet

CLOMIPRAMINE contains Clomipramine, an antidepressant used to treat obsessive-compulsive disorder (OCD), depression, and panic disorder. CLOMIPRAMINE increases the activity of serotonin and noradrenaline (chemical messengers) in the brain that is involved in regulating mood, behavior, and emotions. Thereby, CLOMIPRAMINE helps in relieving depression, lightening the mood, and relieving anxiety symptoms such as fear and panic. CLOMIPRAMINE in combination with other medicines may be used to treat cataplexy (a disorder that causes muscle weakness) which usually affects people suffering from narcolepsy (uncontrollable sleepiness during the daytime).

Directions for Use

Use CLOMIPRAMINE exactly as prescribed by a doctor. Take CLOMIPRAMINE with food and swallow it whole with a glass of water. Do not break, crush or chew it.

Side Effects of Klomin 50mg Tablet

• Dizziness
• Headache
• Drowsiness
• Dry mouth
• Nausea
• Weight gain
• Increased sweating
• Constipation
• Shaking
• Blurred vision
• Erectile dysfunction
• Difficulty in urination

Similar Drugs

For informational purposes only. Consult a doctor before taking any medicines.

In-Depth Precautions and Warning

Drug Warnings

If you are allergic to CLOMIPRAMINE or any other medicines, please tell your doctor. CLOMIPRAMINE is not recommended for children below 17 years of age. Avoid taking CLOMIPRAMINE if you are pregnant as it may cause harm to the fetus. Avoid breastfeeding while taking CLOMIPRAMINE as CLOMIPRAMINE may be excreted in human milk and cause adverse effects in the baby. Therefore, please consult a doctor if you are pregnant, planning for pregnancy, or breastfeeding. CLOMIPRAMINE should be used with caution in elderly patients as there is an increased risk of low sodium levels in the blood.  If you have any self-harming or suicidal thoughts before taking CLOMIPRAMINE, inform your doctor as they may worsen in the initial days of taking CLOMIPRAMINE. Do not take CLOMIPRAMINE with monoamine oxidase inhibitors (MAOIs) such as moclobemide, tranylcypromine and phenelzine used to treat depression as it may cause severe adverse effects. Also, avoid taking CLOMIPRAMINE with buprenorphine as it may cause a serious life-threatening condition. If you have fits, low blood pressure, mania, glaucoma, difficulty in urination, a blood disorder, hyperthyroidism (overactive thyroid gland), severe constipation, pheochromocytoma (tumor of the adrenal gland), low potassium levels in blood, kidney, liver, or heart problems, inform your doctor before taking CLOMIPRAMINE.

Drug Interactions

Drug-Drug Interaction:

CLOMIPRAMINE may have interaction with antiparkinson drugs (selegiline, levodopa), antibiotics (pentamidine, rifampicin), antipsychotic drugs (pimozide), opioid pain killers (buprenorphine, morphine, codeine), blood thinners (warfarin), monoamine oxidase inhibitors used to treat depression (moclobemide, phenelzine, tranylcypromine), antidepressants (fluoxetine, fluvoxamine, amitriptyline, sertraline, venlafaxine, dothiepin, maprotiline), antimanic drug (lithium), anticonvulsants  (phenytoin, carbamazepine, phenobarbital, valproate), painkillers (aspirin), antacids (cimetidine), water tablets (furosemide), anti-allergic drug (terfenadine), medicines used to treat high blood pressure (betanidine, reserpine, guanethidine, clonidine), heart-related medicines (isoprenaline, amiodarone, quinidine, disopyramide, procainamide, epinephrine, diltiazem, verapamil), HIV drugs (ritonavir, indinavir).

Drug-Disease Interaction:

If you have fits, low blood pressure, mania, glaucoma, difficulty in urination, a blood disorder, hyperthyroidism (overactive thyroid gland), severe constipation, pheochromocytoma (tumor of the adrenal gland), low potassium levels in blood, kidney, liver or heart problems, inform your doctor before taking CLOMIPRAMINE.

Safety Advice

ALCOHOL

Avoid consumption of alcohol with CLOMIPRAMINE as it may increase the risk of adverse effects such as drowsiness, blurred vision, or confusion.

PREGNANCY

CLOMIPRAMINE is a Category C pregnancy drug and is not recommended for use during pregnancy as it may cause harm to the unborn baby. Therefore, please consult a doctor if you are pregnant or planning for pregnancy.

BREAST FEEDING

Avoid breastfeeding while taking CLOMIPRAMINE as CLOMIPRAMINE may be excreted in human milk and cause adverse effects in the baby. Therefore, please consult a doctor if you are a breastfeeding mother.

DRIVING

CLOMIPRAMINE may cause dizziness, tiredness, confusion, difficulty in concentrating, or blurred vision. Therefore, avoid driving if you experience any of these symptoms after taking CLOMIPRAMINE.

LIVER

Take CLOMIPRAMINE with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

KIDNEY

If you have any concerns regarding the use of CLOMIPRAMINE in patients with kidney problems, please consult a doctor.