PRODUCT DETAILS

About Gammarp 2.5gm Injection

HUMAN NORMAL IMMUNOGLOBULIN belongs to the class of medications called ‘immunising agents’ used to treat immunoglobulin (antibody) deficiency and certain inflammatory disorders. It is used to treat immunoglobulin deficiency in people with primary immunodeficiency’s or PID (present from birth) and secondary immunodeficiency or SID (developed in the later stages of life). HUMAN NORMAL IMMUNOGLOBULIN is also used to treat inflammatory disorders such as primary immune thrombocytopenia (reduced number of platelets), Guillain-Barre syndrome (short-term inflammation of the peripheral nerves causing weakness of legs and upper limbs), Kawasaki disease (inflammation of blood vessels in children), chronic inflammatory demyelinating polyneuropathy or CIDP (long-term inflammation of peripheral nerves), and multifocal motor neuropathy (progressive disease leading to weakness of arms and legs).

Uses of Gammarp 2.5gm Injection

Immunoglobulin deficiency and inflammatory disorders such as primary immune thrombocytopenia, Guillain-Barre syndrome, Kawasaki disease, chronic inflammatory demyelinating polyneuropathy, and multifocal motor neuropathy.

Medicinal Benefits of Gammarp 2.5gm Injection

HUMAN NORMAL IMMUNOGLOBULIN acts by replacing the deficient antibodies that are necessary to act against infections and inflammation. It works exactly as the immunoglobulins present in the body. Immunoglobulins are an important part of the immune system which recognizes the antigens or foreign elements in the body and cause their destruction. It is used to treat immunoglobulin deficiency in people with primary immunodeficiency’s or PID (present from birth) and secondary immunodeficiency or SID (developed in the later stages of life). HUMAN NORMAL IMMUNOGLOBULIN is also used to treat inflammatory disorders such as primary immune thrombocytopenia (reduced number of platelets), Guillain-Barre syndrome (short-term inflammation of the peripheral nerves causing weakness of legs and upper limbs), Kawasaki disease (inflammation of blood vessels in children), chronic inflammatory demyelinating polyneuropathy or CIDP (long-term inflammation of peripheral nerves), and multifocal motor neuropathy (progressive disease leading to weakness of arms and legs).

Directions for Use

HUMAN NORMAL IMMUNOGLOBULIN is available in the form of injection or infusion. A trained healthcare professional will give you the HUMAN NORMAL IMMUNOGLOBULIN injection or infusion; so do not self-administer. HUMAN NORMAL IMMUNOGLOBULIN injection is given subcutaneously (under the skin), whereas infusion is given via intravenous (into the vein) route.

Side Effects of Gammarp 2.5gm Injection

• Swelling or hardening at the injection site
• Headache
• Pain in the face, back, arms, legs, joints, or neck
• Fever
• Flu-like illness (runny nose and sore throat)
• Blisters in the mouth and throat
• Throat tightness

Similar Drugs

For informational purposes only. Consult a doctor before taking any medicines.

In-Depth Precautions and Warning

Drug Warnings

HUMAN NORMAL IMMUNOGLOBULIN should be used with caution in people with immunoglobulin A (IgA) deficiency (IgA is a type of antibody that protects against infections) as there is an increased risk of allergic reactions. HUMAN NORMAL IMMUNOGLOBULIN may cause a sudden fall in blood pressure with an allergic reaction, including shock, even in patients who have tolerated previous treatment with this medicine. So, it is advised to monitor patients during infusion and at least 20 min after the infusion. If you develop a severe headache, drowsiness, fever, neck stiffness, sensitivity to light, nausea, and vomiting after HUMAN NORMAL IMMUNOGLOBULIN infusion, inform your doctor immediately. It may be a sign of aseptic meningitis syndrome (severe inflammation of the brain's linings). HUMAN NORMAL IMMUNOGLOBULIN should be used with caution in people with obesity or overweight, diabetes, high blood pressure (hypertension), hypovolemia (low blood volume), and blood clotting disorders, as there is a risk of developing a blood clot (very rare effect of HUMAN NORMAL IMMUNOGLOBULIN). So, inform your doctor if you notice any sign of a blood clot such as pain, swelling and unusual warmth of a limb, weakness on one side of the body, confusion, sudden shortness of breath, chest pain worsening on deep breathing, and difficulty speaking. HUMAN NORMAL IMMUNOGLOBULIN should be used with caution in patients with kidney problems or who have taken medicines that may harm kidneys (nephrotoxic drugs) as HUMAN NORMAL IMMUNOGLOBULIN may cause problems with kidney function in these people. In very rare cases, HUMAN NORMAL IMMUNOGLOBULIN may cause non-cardiogenic pulmonary oedema (accumulation of fluid in the lungs' air spaces, which is a non-heart related condition). In such cases, patients may experience breathing difficulty, bluish skin, and very low oxygen levels in the blood.

Drug Interactions

Drug-Drug Interaction:

 HUMAN NORMAL IMMUNOGLOBULIN may interact with loop diuretics (furosemide and ethacrynic acid) and live vaccines (MMR vaccine (measles, mumps, and rubella) and varicella vaccine).

Drug-Disease Interaction:

 HUMAN NORMAL IMMUNOGLOBULIN should be used with caution in people with blood clotting disorders and immunoglobulin A (IgA) deficiency.

Safety Advice

ALCOHOL

HUMAN NORMAL IMMUNOGLOBULIN may not interact with alcohol. However, It is best to avoid alcohol while taking medication

PREGNANCY

HUMAN NORMAL IMMUNOGLOBULIN is probably safe when used in pregnant women.

BREAST FEEDING

HUMAN NORMAL IMMUNOGLOBULIN is probably safe when used in breastfeeding women.

DRIVING

HUMAN NORMAL IMMUNOGLOBULIN may cause dizziness, so do not drive or operate heavy machinery if you feel dizzy.

LIVER

HUMAN NORMAL IMMUNOGLOBULIN should be used with caution in patients with liver diseases. The dose may have to be adjusted by your doctor.

KIDNEY

HUMAN NORMAL IMMUNOGLOBULIN should be used with caution in patients with kidney diseases. The dose may have to be adjusted by your doctor.