PRODUCT DETAILS

About Esmorax-ISR Capsule

ESOMEPRAZOLE+ITOPRIDE is a combination medicine used to treat acidity, gastro-oesophageal reflux disease (GERD), stomach ulcers (peptic ulcers, gastric ulcer due to H pylori), heartburn symptoms, and Zollinger Ellison syndrome. Gastroesophageal reflux disease occurs when stomach acid frequently flows back into the food pipe (esophagus). Peptic ulcers are sores that develop on the inner lining of the intestine and stomach. A gastric ulcer occurs mainly due to a bacteria known as H pylori which irritate and weakens the upper protective layer or mucous of the stomach leading to sores and ulcer. 
 
ESOMEPRAZOLE+ITOPRIDE is a combination of two drugs, namely: Esomeprazole and Itopride. Esomeprazole is a proton pump inhibitor (PPIs) that works by blocking the action of an enzyme called gastric proton pump responsible for the production of stomach acid. Itopride is a gastroprokinetic agent which works by increasing the gastric emptying time, thereby improving the movement/motility of the food pipe, stomach, and intestine. Additionally, Itopride also has anti-emetic action, which controls symptoms of nausea and vomiting. Together, ESOMEPRAZOLE+ITOPRIDE helps in preventing acid reflux, thereby providing relief from symptoms of excessive stomach acid production, which causes an ulcer. 
 
Take ESOMEPRAZOLE+ITOPRIDE 30-60 minutes before food/meal. Swallow ESOMEPRAZOLE+ITOPRIDE as a whole with a glass of water; do not chew, or crush the tablet. You are advised to take ESOMEPRAZOLE+ITOPRIDE for as long as your doctor has prescribed it for you depending on your medical condition. In some cases, you may experience certain common side effects such as headache, flatulence, stomach pain, constipation, and diarrhea. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
 
Inform your doctor before taking ESOMEPRAZOLE+ITOPRIDE if you are allergic to any proton pump inhibitors - PPIs (rabeprazole, pantoprazole, lansoprazole, omeprazole, esomeprazole, etc.) or prokinetic agents (like itopride, metoclopramide, cisapride, domperidone, levosulpiride, etc.) or have a history of gastrointestinal bleeding, mechanical perforation/obstruction, or movement disorder. On long-term treatment, ESOMEPRAZOLE+ITOPRIDE may cause osteoporosis, and hypomagnesemia (low levels of magnesium), and may reduce the absorption of vitamin B12. Do not take ESOMEPRAZOLE+ITOPRIDE if you are pregnant or breastfeeding unless prescribed by the doctor. ESOMEPRAZOLE+ITOPRIDE may cause dizziness, so drive only if you are alert. ESOMEPRAZOLE+ITOPRIDE should not be given to children as safety has not been established. Avoid consuming alcohol along with ESOMEPRAZOLE+ITOPRIDE as it could lead to increased drowsiness and can elevate the production of stomach acid. Keep your doctor informed about all the medicines and your health condition to rule out any side effects.

Uses of Esmorax-ISR Capsule

Hyperacidity, Gastro-oesophageal reflux disease (GERD), Stomach ulcer, Heartburn

Medicinal Benefits of Esmorax-ISR Capsule

ESOMEPRAZOLE+ITOPRIDE is a combination medicine used to treat acidity, gastro-oesophageal reflux disease (GERD), stomach ulcers,s, and heartburn. ESOMEPRAZOLE+ITOPRIDE is a combination of two drugs, namely: Esomeprazole and Itopride. Esomeprazole belongs to a group of medicines called proton pump inhibitors whereas itopride belongs to a group of medicines called prokinetic agents. Esomeprazole works by blocking the action of an enzyme called the gastric proton pump responsible for the production of stomach acid. Itopride works by accelerating the gastric emptying time, thereby increasing the movement of the food pipe, intestine, and stomach. Besides this, Itopride also has anti-emetic action, which prevents the symptom of nausea and vomiting. Together, ESOMEPRAZOLE+ITOPRIDE helps in preventing acid reflux, thereby providing relief from hyperacidity, ulcers,s, and heartburn.  

Directions for Use

Take ESOMEPRAZOLE+ITOPRIDE 30-60 minutes before taking food/meal. Swallow ESOMEPRAZOLE+ITOPRIDE as a whole with a glass of water; do not chew, or crush the tablet. Depending on your medical condition, your doctor will decide how long you need to take ESOMEPRAZOLE+ITOPRIDE.

Side Effects of Esmorax-ISR Capsule

Like all medicines, ESOMEPRAZOLE+ITOPRIDE can also cause side effects, although not everybody experiences them. Headache, flatulence, stomach pain, constipation, and diarrhea are the common side-effects of ESOMEPRAZOLE+ITOPRIDE. Talk to your doctor if you experience any of these side effects persistently.

Similar Drugs

For informational purposes only. Consult a doctor before taking any medicines.

In-Depth Precautions and Warning

Drug Warnings

Do not take ESOMEPRAZOLE+ITOPRIDE if you are allergic to any of its contents; if you are taking nelfinavir (anti-HIV); if you have a gastrointestinal hemorrhage, mechanical obstruction or perforation, epilepsy, mania, porphyria, or cardiac impairment. Inform your doctor before taking ESOMEPRAZOLE+ITOPRIDE if you have severe liver or kidney problems; or if you are due to have Chromogranin A test. Consult your doctor if you experience unexplained weight loss, stomach pain, indigestion, vomit food or blood, or if you pass black stools. On long-term treatment, ESOMEPRAZOLE+ITOPRIDE may cause osteoporosis, and hypomagnesemia (low levels of magnesium), and may reduce the absorption of vitamin B12. Do not take ESOMEPRAZOLE+ITOPRIDE if you are pregnant or breastfeeding unless prescribed by the doctor. ESOMEPRAZOLE+ITOPRIDE may cause dizziness, so drive only if you are alert. ESOMEPRAZOLE+ITOPRIDE should not be given to children as safety has not been established. Avoid consuming alcohol along with ESOMEPRAZOLE+ITOPRIDE as it could lead to increased drowsiness and can elevate the production of stomach acid. 

Drug Interactions

Drug-Drug Interaction:

ESOMEPRAZOLE+ITOPRIDE may have interaction with pain killers (aspirin, naproxen), an antidepressant (duloxetine, citalopram), anti-anxiety (diazepam), hypothyroidism (levothyroxine), blood thinner (clopidogrel), and vitamin (cyanocobalamin).

Drug-Disease Interaction:

ESOMEPRAZOLE+ITOPRIDE may have interactions with gastrointestinal bleeding, mechanical obstruction or perforation, Clostridium difficile-associated diarrhea (CDAD), liver disease, bone fractures, hypomagnesemia (low levels of magnesium).

Safety Advice

ALCOHOL

Avoid consumption of alcohol while taking ESOMEPRAZOLE+ITOPRIDE. Alcohol intake leads to increased production of stomach acid, thereby increasing acidity and heartburn.

PREGNANCY

Consult your doctor before taking ESOMEPRAZOLE+ITOPRIDE if you are pregnant; your doctor will prescribe only if the benefits outweigh the risks.

BREAST FEEDING

Consult your doctor before taking ESOMEPRAZOLE+ITOPRIDE if you are breastfeeding; your doctor will decide whether ESOMEPRAZOLE+ITOPRIDE can be taken by breastfeeding mothers or not.

DRIVING

ESOMEPRAZOLE+ITOPRIDE may cause dizziness and blurred vision. Do not drive or operate machinery unless you are alert.

LIVER

Dose adjustment may be needed. Consult your doctor before taking ESOMEPRAZOLE+ITOPRIDE if you have a liver impairment or any concerns regarding this.

KIDNEY

• Dose adjustment may be needed. Consult your doctor before taking ESOMEPRAZOLE+ITOPRIDE if you have kidney impairment or any concerns regarding this.