PRODUCT DETAILS

About Bupine 0.3mg Injection

BUPRENORPHINE belongs to a class of drugs called 'opioid analgesic' primarily used to treat opioid addiction (narcotics) like morphine, heroin, etc. In some cases, it also used to treat prevent and treat moderate to severe pain. Drug addiction, also called substance use disorder, is a disease that affects a person's brain and behaviour and leads to an inability to control the use of a legal or illegal drug or medication.

BUPRENORPHINE contains 'Buprenorphine' an opioid partial agonist-antagonists that prevent withdrawal symptoms in patients who stop taking opioid drugs by producing similar effects to these drugs. It has been approved for the treatment of narcotic-use disorders.  A combination of buprenorphine and naloxone is prescribed for use in the treatment of opioid dependence. It also provides pain relief by acting on specific receptors in the brain and helps in relieving pain.

Uses of Bupine 0.3mg Injection

Opioid (drug) addiction, Opioid (drug) detoxification, Pain

Medicinal Benefits of Bupine 0.3mg Injection

The BUPRENORPHINE contains Buprenorphine as a substitution (replacement) treatment in patients who are addicted to opioid drugs (heroin and morphine, etc.). It prevents or reduces the unpleasant withdrawal symptoms experienced when addicts stop using opioid drugs. It also provides pain relief by acting on specific receptors in the brain and helps in relieving pain. Compared to other opioid analgesics like methadone, BUPRENORPHINE has the advantage of having less sedation (sleepiness), decreased respiratory depression, decreased risk of diversion, less withdrawal symptoms and lower risk of toxicity at higher doses. 

Directions for Use

Use BUPRENORPHINE only when prescribed by a doctor. Always take BUPRENORPHINE exactly as your doctor advised you. Sublingual tablet: Place the tablet under your tongue and allow it to dissolve with your mouth closed. Do not chew the tablet or swallow it whole. Injection: It can be given in the muscles (intramuscular/IM) or in the veins (intravenous/IV). Do not self administer. Any trained healthcare professional will administer it.

Side Effects of Bupine 0.3mg Injection

• Weakness
• Anxiety
• Nervousness
• Dizziness
• Drowsiness
• Headache
• Orthostatic hypotension (a sudden dip of blood pressure on standing)
• Constipation
• Diarrhoea
• Nausea
• Vomiting
• Sweating

Similar Drugs

For informational purposes only. Consult a doctor before taking any medicines.

In-Depth Precautions and Warning

Drug Warnings

Please do not stop taking BUPRENORPHINE suddenly as it may cause withdrawal symptoms. Avoid frequent or high doses as it may lead to addiction. If you are known to be allergic to BUPRENORPHINE or any other medicines, please tell your doctor.  Do not take BUPRENORPHINE if you are pregnant or breastfeeding as it may cause adverse effects in the baby. BUPRENORPHINE is not recommended for children below 18 years of age.  Avoid consuming alcohol with BUPRENORPHINE as it may increase the risk of side effects. Do not use this medicine if you have used an MAO inhibitor (antidepressants) in the past 14 days as a dangerous drug interaction could occur. BUPRENORPHINE should be taken with extreme caution in patients who have a history of alcoholism or drug abuse. Inform your doctor if you have severe breathing problems, asthma, delirium tremens (confusion and shaking after stopping drinking alcohol), hallucinations (seeing and hearing things that are not there), kidney or liver problems, head injury or brain disease, low blood pressure, urinary disorders (especially linked to enlarged prostate), thyroid problems, adrenocortical disorder (Addison’s disease), depression or other conditions that are treated with antidepressants. 

Drug-Drug Interaction:

BUPRENORPHINE may have interaction with benzodiazepines (diazepam, temazepam ), pain killers (pentazocine, nalbuphine, codeine, dihydrocodeine, methadone, morphine), anti-depressants (moclobemide, tranylcypromine, citalopram, escitalopram, fluoxetine, fluvoxamine, paroxetine, sertraline, duloxetine, venlafaxine, amitriptyline, doxepin, trimipramine), antihistamine (promethazine, chlorphenamine), blood thinners (warfarin), anti-anxiety drugs (alprazolam), fits related medicines (carbamazepine), medicines used to prevent nausea (ondansetron), antifungal drugs (ketoconazole), antibiotic (ciprofloxacin, erythromycin), anticancer drugs (ceritinib, lapatinib), immunosuppressants (fingolimod), antipsychotics (droperidol), and HIV/AIDS drugs (saquinavir).