PRODUCT DETAILS

About Apriglim-M 2 Tablet PR

GLIMEPIRIDE+METFORMIN belongs to a class of medicines called anti-diabetic drugs used in the treatment of type 2 diabetes, especially in patients whose blood sugar levels are not controlled by diet and exercise alone. Type 2 diabetes is a chronic (long-lasting) condition that affects the way our body processes glucose. People with type 2 diabetes either do not produce enough insulin, or the insulin produced is unable to perform its function in the body (insulin resistance).

Uses of Apriglim-M 2 Tablet PR

Type 2 diabetes mellitus

Medicinal Benefits of Apriglim-M 2 Tablet PR

GLIMEPIRIDE+METFORMIN contains Glimepiride and Metformin used in the treatment of type 2 diabetes. Glimepiride stimulates cells in the pancreas that produce insulin which helps to remove sugar from the blood. Metformin PR is a prolonged-release formulation that releases the drug in smaller portions over a longer duration of time. Metformin reduces the sugar production by cells in the liver and delays sugar absorption from the intestines. Also, it increases the sensitivity of muscle cells to insulin which enables these cells to remove sugar more effectively from the blood.

Directions for Use

Tablet: Swallow the tablet as a whole with a glass of water. Do not crush or break it.

Side Effects of Apriglim-M 2 Tablet PR

• Stomach pain
• Nausea
• Diarrhoea
• Vomiting
• Headache
• Metallic taste

Similar Drugs

For informational purposes only. Consult a doctor before taking any medicines.

In-Depth Precautions and Warning

Drug Warnings

If you are allergic to GLIMEPIRIDE+METFORMIN or any other medicines, please tell your doctor. GLIMEPIRIDE+METFORMIN is not recommended for children. Avoid breastfeeding while taking GLIMEPIRIDE+METFORMIN as it may be excreted in human milk. If you are pregnant or planning for pregnancy, please inform your doctor before taking GLIMEPIRIDE+METFORMIN as it may harm the unborn baby. Avoid alcohol consumption with GLIMEPIRIDE+METFORMIN as it may increase the risk of lactic acidosis (accumulation of lactic acid in the body). Drive only if you are alert after taking GLIMEPIRIDE+METFORMIN. Take short, frequent meals and avoid prolonged fasting while taking GLIMEPIRIDE+METFORMIN. Beware of symptoms of hypoglycaemia (low blood sugar) which include sweating, dizziness, palpitations, shivering, intense thirst, dry mouth, dry skin, frequent urination etc. Whenever you experience any of these symptoms, immediately consume 5-6 candies or 3 glucose biscuits or 3 teaspoons of honey/sugar and also consult your doctor. Make sure to carry these with you at all times, especially during long travels.

Drug Interactions

Drug-Drug Interaction:

 GLIMEPIRIDE+METFORMIN may have interaction with antibiotics (rifampicin, trimethoprim), calcium channel blockers (verapamil), antacid (cimetidine), HIV/AIDS drugs (dolutegravir), heart-related medicine (ranolazine), anticancer drugs (vandetanib, crizotinib, olaparib), antifungals (fluconazole, miconazole), water pill (acetazolamide), antidiabetic drug (insulin), anticonvulsants (phenytoin).

Drug-Disease Interaction:

 If you have severe infections, uncontrolled diabetes, lactic acidosis or ketoacidosis (accumulation of ketone bodies in the blood), dehydration, liver or kidney problems, inform your doctor before taking GLIMEPIRIDE+METFORMIN.

Safety Advice

ALCOHOL

You are recommended to avoid consumption of alcohol with GLIMEPIRIDE+METFORMIN as it may increase the risk of lactic acidosis (accumulation of lactic acid in the body).

PREGNANCY

GLIMEPIRIDE+METFORMIN is not recommended for pregnant women as it may harm the unborn baby. Please consult a doctor if you are pregnant or planning for pregnancy.

BREAST FEEDING

Avoid breastfeeding while taking GLIMEPIRIDE+METFORMIN as it may be excreted in breastmilk and cause adverse effects in the baby. Therefore, please consult a doctor before using GLIMEPIRIDE+METFORMIN if you are breastfeeding.

DRIVING

GLIMEPIRIDE+METFORMIN may decrease alertness in some people. Therefore, drive only if you are alert after taking GLIMEPIRIDE+METFORMIN.

LIVER

Take GLIMEPIRIDE+METFORMIN with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

KIDNEY

Take GLIMEPIRIDE+METFORMIN with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.