PRODUCT DETAILS

About Tramef 500mg/250mg Tablet

MEFENAMIC ACID+TRANEXAMIC ACID is a combination medicine used to treat dysmenorrhea (period pain) and menorrhagia (heavy menstrual bleeding). Besides this, MEFENAMIC ACID+TRANEXAMIC ACID is also used to treat severe blood loss, swelling in various body parts, fever, inflammation, and migraine headache. Menstrual cramps, also known as dysmenorrhea, is characterised with cramps and pain during menstruation. Menorrhagia is a condition with abnormally heavy or prolonged bleeding during menstruation/periods.

MEFENAMIC ACID+TRANEXAMIC ACID is a combination of two drugs: Tranexamic acid (anti-fibrinolytic) and Mefenamic acid (NSAID). Tranexamic acid helps the body's natural blood clot process by preventing fibrin's breakdown, this stops fibrinolysis, a process that stops blood clot formation. Mefenamic acid works by blocking the effect of a chemical messenger known as cyclo-oxygenase (COX) enzymes that make another chemical prostaglandins (PG). By blocking COX enzyme's effect, lesser PGs are produced, which reduces mild to moderate pain and inflammation.

Uses of Tramef 500mg/250mg Tablet

Dysmenorrhea (period pain) and menorrhagia (heavy menstrual bleeding).

Medicinal Benefits of Tramef 500mg/250mg Tablet

MEFENAMIC ACID+TRANEXAMIC ACID is a combination of two drugs, namely: Tranexamic acid and Mefenamic acid. MEFENAMIC ACID+TRANEXAMIC ACID is used to treat abdominal pain, dysmenorrhea (period pain) and menorrhagia (heavy menstrual bleeding). Additionally, MEFENAMIC ACID+TRANEXAMIC ACID is also used to treat severe blood loss, swelling in various body parts, fever, inflammation, and migraine headache. Tranexamic acid is an anti-fibrinolytic that helps the body's natural blood clot process by preventing fibrin's breakdown, this stops fibrinolysis, a process that stops blood clot formation. Mefenamic acid is an NSAID which works by blocking the effect of a chemical messenger in your body, known as cyclo-oxygenase (COX) enzymes that make other chemical prostaglandins (PG). By blocking COX enzyme's effect, lesser PGs are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site. Together, MEFENAMIC ACID+TRANEXAMIC ACID helps in treating heavy bleeding and pains/cramps during periods.

Directions for Use

Take MEFENAMIC ACID+TRANEXAMIC ACID with food to prevent stomach upset. Swallow MEFENAMIC ACID+TRANEXAMIC ACID as a whole with a glass of water, do not chew, or break the tablet. Based on your medical condition, your doctor will decide how long you need to take MEFENAMIC ACID+TRANEXAMIC ACID.

Side Effects of Tramef 500mg/250mg Tablet

• Nausea
• Vomiting
• Diarrhoea
• Indigestion
• Heartburn
• Headache
• Musculoskeletal pain
• Stomach pain

Similar Drugs

For informational purposes only. Consult a doctor before taking any medicines.

In-Depth Precautions and Warning

Drug-Drug Interaction:

MEFENAMIC ACID+TRANEXAMIC ACID may interact with pain killers (ibuprofen, celecoxib), anti-depressant (duloxetine, fluoxetine, sertraline), fibrinolytic medicine, birth control pills, drugs that prevent bleeding (factor IX complex, anti-inhibitor coagulant concentrates), blood thinners (anticoagulants such as warfarin, heparin)

Safety Advice

ALCOHOL

Avoid consumption of alcohol while taking MEFENAMIC ACID+TRANEXAMIC ACID as it may increase drowsiness. It can also increase the risk of stomach bleeding.

DRIVING

MEFENAMIC ACID+TRANEXAMIC ACID may cause drowsiness and dizziness. Do not drive or operate machinery unless you are alert.

LIVER

Dose adjustment may be needed in patients with liver impairment.

KIDNEY

Dose adjustment may be needed in patients with liver impairment.