PRODUCT DETAILS

About Seminerve NT 400mg/10mg Tablet

GABAPENTIN+NORTRIPTYLINE belongs to a combination medicine of anticonvulsant (Gabapentin) and antidepressant (Nortriptyline) used for the management of neuropathic pain. It is a chronic progressive nerve disease that causes nerve pain.

GABAPENTIN+NORTRIPTYLINE contains Gabapentin and Nortriptyline. Gabapentin works by binding to the specific site on voltage-gated calcium channels; this helps in relieving nerve pain and lowers the risk of seizures. Nortriptyline works by preventing the released chemical messenger in the brain (serotonin and noradrenaline) from being reabsorbed back into the nerve cells (neuron) in the brain. As a result, it prolongs the effect of serotonin and noradrenaline in the brain, and over time, this helps to relieve depression and lighten the mood.

Uses of Seminerve NT 400mg/10mg Tablet

Neuropathic pain

Medicinal Benefits of Seminerve NT 400mg/10mg Tablet

GABAPENTIN+NORTRIPTYLINE is used to treat neuropathic pain. GABAPENTIN+NORTRIPTYLINE is a combination of two drugs: Gabapentin and Nortriptyline. Gabapentin belongs to a class of drugs called anti-convulsants whereas Nortriptyline belongs to tricyclic antidepressants. Gabapentin works by binding to the specific site on voltage-gated calcium channels; this helps in relieving nerve pain and lowers the risk of seizures. On the other hand, Nortriptyline works by preventing the released chemical messenger in brains (serotonin and noradrenaline) from being reabsorbed back into the nerve cells (neuron) in the brain. As a result, it prolongs the effect of serotonin and noradrenaline in the brain and over time, this helps to relive depression and lighten the mood.

Directions for Use

Take GABAPENTIN+NORTRIPTYLINE with or without food. Swallow GABAPENTIN+NORTRIPTYLINE as a whole with a glass of water; do not chew, or break the tablet. Based on your medical condition, your doctor will decide how long you need to take GABAPENTIN+NORTRIPTYLINE.

Side Effects of Seminerve NT 400mg/10mg Tablet

Like all medicines, GABAPENTIN+NORTRIPTYLINE can also cause side-effects, although not everybody experiences them. Dizziness, sleepiness, tiredness, headache, nausea, vomiting, blurred vision, dry mouth, dry eye syndrome and tingling sensations are the common side-effects of GABAPENTIN+NORTRIPTYLINE. Please consult your doctor if you experience any of these side-effects persistently.

Similar Drugs

For informational purposes only. Consult a doctor before taking any medicines.

In-Depth Precautions and Warning

Drug Warnings

Do not take GABAPENTIN+NORTRIPTYLINE if you are allergic to any of its contents. Inform your doctor before taking GABAPENTIN+NORTRIPTYLINE if you have or had heart problems or bipolar syndrome. Please do not stop taking GABAPENTIN+NORTRIPTYLINE without consulting your doctor as it could cause withdrawal symptoms. Do not take GABAPENTIN+NORTRIPTYLINE if you are pregnant or breastfeeding unless prescribed by the doctor. GABAPENTIN+NORTRIPTYLINE causes drowsiness and dizziness, so drive only if you are alert. GABAPENTIN+NORTRIPTYLINE should not be given to children unless prescribed. Avoid consuming alcohol along with GABAPENTIN+NORTRIPTYLINE as it could lead to increased dizziness and sleepiness. For this reason you should avoid driving and operate heavy machinery. Consult your doctor immediately if you experience suicidal tendencies. Keep your doctor informed about your health condition and medicines to rule out any side-effects. Prolonged intake of GABAPENTIN+NORTRIPTYLINE can cause side effects like dry mouth, dry eyes, and dizziness. Let your doctor know about these side effects if it persists. 

Drug Interactions

Drug-Drug Interaction:

GABAPENTIN+NORTRIPTYLINE may have interaction with hypnotics (zolpidem), antidepressants (citalopram, duloxetine, escitalopram, fluoxetine, bupropion, sertraline), pain killer (codeine, hydrocodone, acetaminophen, oxycodone, tramadol, methadone), anti-histamine (diphenhydramine, cetirizine), muscle relaxant (cyclobenzaprine), anti-convulsant (clonazepam, pregabalin, topiramate), anti-thyroid (levothyroxine), anti-anxiety (diazepam, alprazolam), anti-emetic (ondansetron), anti-psychotic (quetiapine), and drugs used to treat opioid misuse (naloxone, buprenorphine).

Drug-Disease Interaction:

GABAPENTIN+NORTRIPTYLINE may have interactions with disease conditions such as anticholinergic effects, heart problems, pheochromocytoma (tumour of the adrenal gland), depression, seizures, bone marrow suppression, diabetes, schizophrenia, bipolar disorder, glaucoma, diabetes, thyroid problems, suicidal tendency, haemodialysis, kidney and liver problems.

Safety Advice

ALCOHOL

Avoid consumption of alcohol while taking GABAPENTIN+NORTRIPTYLINE as it may increase dizziness and sleepiness.

PREGNANCY

Avoid taking GABAPENTIN+NORTRIPTYLINE if you are pregnant unless prescribed by a doctor. Please consult your doctor if you have any concerns regarding this, your doctor will prescribe only if the benefits outweigh the risks.

BREAST FEEDING

Consult your doctor before taking GABAPENTIN+NORTRIPTYLINE; your doctor will decide whether GABAPENTIN+NORTRIPTYLINE can be taken by breastfeeding mothers or not.

DRIVING

GABAPENTIN+NORTRIPTYLINE causes drowsiness, sleepiness and tiredness. Do not drive or operate machinery unless you are alert.

LIVER

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

KIDNEY

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.