PRODUCT DETAILS

About Rexnip-P Tablet

NIMESULIDE+PARACETAMOL belongs to a class of painkillers called non-steroidal anti-inflammatory drugs (NSAIDs). Pain can be temporary (acute) or long-lasting (chronic) in nature. Acute pain is caused by damage to the tissues of the muscle, bone or other organs for a short time. While, chronic pain lasts for a long duration and is caused due to pathologies like nerve damage, osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, etc. Besides this, it is also useful for dental pain, which can occur due to damage to the tooth nerve, infection, decay, extraction or injury.

NIMESULIDE+PARACETAMOL is composed of two medicines: Nimesulide and Paracetamol. Together it relieves symptoms of arthritis, dysmenorrhea (painful periods or menstrual cramps) and reduces fever. Nimesulide is known to have an analgesic and anti-inflammatory effect for reducing mild to moderate pain. It works by blocking the effect of a chemical known as prostaglandin responsible for inducing pain and inflammation in our body. Paracetamol acts as a mild analgesic and antipyretic (fever reducer). It lowers the elevated body temperature and mild pain by inhibiting the synthesis of a chemical messenger (prostaglandin) and promoting heat loss (through sweating) that helps reset the hypothalamic thermostat. Together it helps in reducing mild to moderate pain in a shorter duration.

Uses of Rexnip-P Tablet

Pain relief

Medicinal Benefits of Rexnip-P Tablet

NIMESULIDE+PARACETAMOL is composed of nimesulide and paracetamol, primarily used to treat mild to moderate pain. NIMESULIDE+PARACETAMOL is prescribed mainly to treat pain and get relief from discomfort caused by conditions like tooth pain, arthritis, period pain and other types of short-term pains. It helps in treating pain by blocking the chemical messenger in the brain responsible for causing fever, pain and inflammation. Nimesulide works by blocking the effect of a chemical known as prostaglandin responsible for inducing pain and inflammation in our body. On the other hand, Paracetamol lowers the elevated body temperature and mild pain by inhibiting prostaglandin synthesis by promoting heat loss (through sweating) that helps reset the hypothalamic thermostat. Paracetamol has got the advantage of producing less gastric irritation compared to other painkillers like aspirin.

Directions for Use

Take it with food or milk to avoid upsetting the stomach. Do not chew, crush or break the tablet.

Side Effects of Rexnip-P Tablet

Most of the side effects of NIMESULIDE+PARACETAMOL do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor. The most common side effects of NIMESULIDE+PARACETAMOL are loss of appetite (in case of liver condition), nausea, vomiting, abdominal pain, persistent tiredness or dark/discoloured urine. It is not necessary for everyone to experience the above side effects. In case of any discomfort, speak with your doctor.

Similar Drugs

For informational purposes only. Consult a doctor before taking any medicines.

In-Depth Precautions and Warning

Drug Warnings

NIMESULIDE+PARACETAMOL is contraindicated in patients with a history of hypersensitivity (allergic) reaction to NIMESULIDE+PARACETAMOL, paracetamol or nimesulide or other pain killers. Please inform your doctor before starting NIMESULIDE+PARACETAMOL if you have an active stomach ulcer, recent gastrointestinal bleeding, asthma, recent by-pass heart surgery or severe kidney/liver impairment. Nimesulide present in NIMESULIDE+PARACETAMOL is known to affect fertility, so if you are planning for pregnancy contact doctor. NIMESULIDE+PARACETAMOL should be avoided in both pregnant (especially last trimester of pregnancy) and breastfeeding women, as it may pass the milk affecting the baby. Patients with heart diseases and recent stroke (bleeding in the brain) should not take NIMESULIDE+PARACETAMOL as a substitute for aspirin. It should not be given to children (below 12 years) with symptoms of fever and chills or suffering from influenza (flu) or chickenpox.

Drug Interactions

Drug-Drug Interaction:

NIMESULIDE+PARACETAMOL is shown to interact with various drugs. Some of them include lithium, anticancer/antimetabolites (methotrexate), blood thinner or anticoagulant (warfarin, coumadin, aspirin), blood pressure or heart medicine, nausea medicine (metoclopramide, domperidone), diuretic/water pills (thiazides, furosemide), steroid medicine (prednisone), quinolones antibiotics (ciprofloxacin), respiratory medicines (theophyllines, ephedrine), immune system affecting medicine (cyclosporine), cholesterol-reducing medicine (colestyramine) and antidepressants (duloxetine). These drugs may affect the working of NIMESULIDE+PARACETAMOL and may alter its efficacy.

Drug-Disease Interaction:

NIMESULIDE+PARACETAMOL should not recommend for people having bleeding disorders, like haemophilia, von Willebrand disease, or low blood platelets. Besides this, it should not be given to children suffering from influenza (flu) or chickenpox. It should also be avoided in case of the presence of gastric or duodenal ulcers.

Safety Advice

ALCOHOL

Taking NIMESULIDE+PARACETAMOL with alcohol may cause dizziness or drowsiness. Besides this, it can also damage your liver if taken for a longer duration. So, avoid or limit the intake of alcoholic beverages with NIMESULIDE+PARACETAMOL.

PREGNANCY

Use of NIMESULIDE+PARACETAMOL during pregnancy is not recommended as taking this medicine during the last 3 months of pregnancy may harm the unborn baby. Consult your doctor for further advice.

BREAST FEEDING

Use of NIMESULIDE+PARACETAMOL during breastfeeding is not recommended as it may pass through the milk and harm the baby. Consult your doctor for further advice.

DRIVING

After taking NIMESULIDE+PARACETAMOL, you may notice dizziness, sleepiness, drowsiness. So, you should stop taking NIMESULIDE+PARACETAMOL and contact your doctor.

LIVER

NIMESULIDE+PARACETAMOL to be taken with caution, especially if you have a history of liver diseases/conditions. The dose may have to be adjusted by your doctor.

KIDNEY

NIMESULIDE+PARACETAMOL to be taken with caution, especially if you have a history of Kidney diseases/conditions. The dose may have to be adjusted by your doctor.