PRODUCT DETAILS

About Rebustat 40mg Tablet

FEBUXOSTAT belongs to a class of anti-gout medications, also known as xanthine oxidase inhibitors, widely used for the prevention of severe gout attacks or flares. Gout is a chronic condition that occurs due to the deposition of uric acid crystals in the joints. It is characterized by intense pain and swelling in the affected joints. FEBUXOSTAT prevents the sudden attacks of pain caused by severe gout and also decreases the pain, swelling, and inflammation.

FEBUXOSTAT contains febuxostat. It works by inhibiting the enzyme xanthine oxidase (the enzyme that helps your body to make the uric acid), thereby reducing the level of uric acid that is made in your body. Thus, it reduces the inflammation caused by uric acid crystals in affected joints, thereby reducing pain swelling, and inflammation. FEBUXOSTAT is used to prevent gout attacks or flares.

FEBUXOSTAT is an orally administered drug. Swallow the tablet as a whole with a glass of water. Do not chew, bite, or break it. Your doctor will advise you how often you take off FEBUXOSTAT based on your medical condition. The common side effects of FEBUXOSTAT are nausea, rash, dizziness, diarrhea, pain, rash, inaccurate liver function test results, gout flare-ups (intense joint pain that comes on suddenly, often in the middle of the night), localized swelling due to retention of fluids in tissues (edema). Most of these side effects of FEBUXOSTAT do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Do not stop taking FEBUXOSTAT of your own. Stopping it may worsen your condition and increase the risk of increased uric acid levels and future gout attacks. Inform your doctor if you have allergic to FEBUXOSTAT or any other medicines, have a heart problem (FEBUXOSTAT may cause heart problems that can lead to heart attack), kidney/liver disease. Some people experience more gout flare-ups when you start taking FEBUXOSTAT. You should continue taking this drug even if gout flare-ups occur. Your doctor may give you combination therapy to prevent flare-ups when you start FEBUXOSTAT. The safety and effectiveness in children less than 18 years of age have not been established, so FEBUXOSTAT should not be given to them. If you are pregnant or breastfeeding, it is advised to inform your doctor before using FEBUXOSTAT.

Uses of Rebustat 40mg Tablet

Treatment of severe gout, prevention of gout attacks

Medicinal Benefits of Rebustat 40mg Tablet

FEBUXOSTAT is a class of medications called xanthine oxidase (enzyme that helps your body to make the uric acid) inhibitors. It works by inhibiting the enzyme xanthine oxidase, thereby reducing the level of uric acid that is made in your body. Thus, it reduces the inflammation caused by uric acid crystals in affected joints, thereby reducing pain swelling and inflammation. FEBUXOSTAT is used to prevent gout attacks or flares.

Directions for Use

Take FEBUXOSTAT with or without food. Do not chew, crush, or break the tablet. Swallow it as a whole with a glass of water. FEBUXOSTAT should not be taken unless prescribed by a doctor. Your doctor will advise for how long you need to take FEBUXOSTAT based on your medical condition.

Side Effects of Rebustat 40mg Tablet

Like all medicines, FEBUXOSTAT can also cause side effects, although not everybody experiences them. The common side effects of FEBUXOSTAT include nausea, rash, dizziness, diarrhea, joint pain, rash, inaccurate liver function test results, gout flare-ups (intense joint pain that comes on suddenly, often in the middle of the night), localized swelling due to retention of fluids in tissues (edema). These side effects gradually resolve over time. If the condition worsens or there are any abnormal signs, reach out to the doctor.

Similar Drugs

For informational purposes only. Consult a doctor before taking any medicines.

In-Depth Precautions and Warning

Drug Warnings

You should avoid taking FEBUXOSTAT if you are allergic to FEBUXOSTAT, or have heart-related problems, as it increases the risk of a heart attack. It should be used with caution in patients with kidney problems and blood disorders. Caution is required before taking FEBUXOSTAT if you are pregnant or planning to become pregnant, or breastfeeding mother. The safety and effectiveness in children less than 18 years of age have not been established, so FEBUXOSTAT should not be given to them.

Drug Interactions

Drug-Drug Interaction:

FEBUXOSTAT interacts with anticancer (mercaptopurine, methotrexate) immunosuppressants (azathioprine), antidiabetic (rosiglitazone), antiasthma (theophylline).

Drug-Disease Interaction:

Brief your doctor if you have a medical history of allergic reactions to medicines,  hyperuricemia (an abnormally high level of uric acid in the blood), heart diseases, liver or kidney diseases before taking FEBUXOSTAT.

Safety Advice

ALCOHOL

You should avoid taking alcohol while taking FEBUXOSTAT because alcohol may affect FEBUXOSTAT effectiveness.

PREGNANCY

FEBUXOSTAT should not be taken until prescribed. Your doctor will weigh the benefits and any potential risks before prescribing them to you. Please consult your doctor.

BREAST FEEDING

There is limited data on how FEBUXOSTAT affects breastfeeding. Please consult your doctor before starting FEBUXOSTAT.

DRIVING

Do not drive or operate machinery if you experience sleepiness, blurred vision, numbness, or tingling sensation while using FEBUXOSTAT. Seek medical attention if the symptoms persist longer.

LIVER

Let your doctor know if you have any history of liver disease or hepatic impairment. Your doctor will weigh the benefits and any potential risks before prescribing FEBUXOSTAT.

KIDNEY

FEBUXOSTAT should be used with caution in patients with renal impairment. The doctor may adjust the dose depending on your condition.