PRODUCT DETAILS

About Neksico 40 Tablet

ESOMEPRAZOLE belongs to the class of drugs known as Proton pump inhibitor which reduces the amount of acid your stomach makes. It treats gastroesophageal reflux disease (GERD), stomach ulcers and Zollinger Ellison syndrome (overproduction of acid due to pancreatic tumour).

ESOMEPRAZOLE helps in reducing the stomach acid by blocking the actions of an enzyme (H+/K+ ATPase or gastric proton pump). This proton pump lies in the cells of the stomach wall responsible for the release of gastric acid secretion damaging tissues in the food pipe, stomach, and duodenum. ESOMEPRAZOLE prevents the release of stomach acid and relieves symptoms of food pipe lining inflammation (esophagitis), and gastroesophageal reflux disease (GERD), or heartburn.

ESOMEPRAZOLE can be prescribed to adults and children aged 12 years and over. It is better to take ESOMEPRAZOLE an hour before a meal. ESOMEPRAZOLE should be swallowed whole with a glass of water. Do not chew, crush, or break it. Besides this, ESOMEPRAZOLE is also available in liquid form for those who cannot swallow tablets or capsules. Do not take ESOMEPRAZOLE for more than 4 weeks of duration without consulting the doctor. You can increase the efficacy of ESOMEPRAZOLE by taking a small meal or snacks frequently. Try to avoid caffeine-containing beverages (coffee, tea), spicy/deep-fried/processed foods, carbonated beverages, and acidic foods like citrus fruits/vegetables (tomatoes).

An adult taking ESOMEPRAZOLE might have common side effects like headache, diarrhoea, nausea, abdominal pain, vomiting, flatulence, dizziness, and arthralgia (joint pain). In the case of children taking ESOMEPRAZOLE might report upper respiratory tract infections (URI), headache, fever, diarrhoea, vomiting, rash, and abdominal pain.  These side effects are temporary and may get resolved after some time however if this side persists contact the doctor.

ESOMEPRAZOLE is safe for pregnant and breastfeeding mothers but should be taken only after consulting a doctor. Tell your doctor if you have stomach or intestinal cancer, liver problem, are allergic to ESOMEPRAZOLE or will have an endoscopy in the future. Prolonged intake of ESOMEPRAZOLE may cause deficiency of Vitamin B12 and low levels of calcium, magnesium, and Vitamin D leading to osteoporosis.

Uses of Neksico 40 Tablet

Hyperacidity, Heartburn, Stomach ulcer, Zollinger-Ellison syndrome

Medicinal Benefits of Neksico 40 Tablet

ESOMEPRAZOLE is effective at healing erosive esophagitis (inflammation of food pipe), relieving symptoms of gastroesophageal reflux disease (heartburn), and Zollinger-Ellison syndrome. ESOMEPRAZOLE works by irreversibly blocking the proton pump gate (which secretes stomach acid). It can be prescribed to all age groups including special populations like the elderly, pregnant, lactating mothers, kidney, and liver disease patients. Usually, no dosage adjustment is required for these groups.

Directions for Use

It is better to take ESOMEPRAZOLE an hour before a meal. ESOMEPRAZOLE should be swallowed whole with a glass of water. Do not chew, crush, or break it. Besides this, ESOMEPRAZOLE is also available in liquid form for those who cannot swallow tablets or capsules. Do not take ESOMEPRAZOLE for more than 4 weeks of duration without consulting the doctor.

Side Effects of Neksico 40 Tablet

An adult taking ESOMEPRAZOLE might have common side effects like headache, diarrhea, nausea, abdominal pain, vomiting, flatulence, dizziness, and arthralgia (joint pain). In the case of children taking ESOMEPRAZOLE might report upper respiratory tract infections (URI), headache, fever, diarrhea, vomiting, rash, and abdominal pain. These side effects are temporary and may get resolved after some time however if this side persists contact the doctor.

Similar Drugs

For informational purposes only. Consult a doctor before taking any medicines.

In-Depth Precautions and Warning

Drug Warnings

You should avoid taking ESOMEPRAZOLE if you are allergic to ESOMEPRAZOLE or proton pump inhibitors, have gastric cancer, have liver disease, have low magnesium level (osteoporosis), low vitamin B12, are pregnant or planning for pregnancy, and breastfeeding mothers. ESOMEPRAZOLE may interact with a blood thinner (warfarin), antifungal (ketoconazole), anti-HIV drug (atazanavir, nelfinavir), iron supplements, ampicillin antibiotic, anti-cancer drug (methotrexate). Let your doctor know if you are taking these medicines. Prolonged intake of ESOMEPRAZOLE may cause lupus erythematosus (an inflammatory condition in which the immune system attacks its own tissues), Vitamin B12, and magnesium deficiency. Intake of ESOMEPRAZOLE may mask the symptom of gastric cancer, so if you have any severe stomach pain or gastric bleeding (blood in mucous or stool) immediately consult the doctor. 

Drug Interactions

Drug-Drug Interaction:

ESOMEPRAZOLE may interact with a blood thinner (clopidogrel, warfarin), antifungal (ketoconazole, voriconazole, itraconazole, posaconazole), anti-HIV drug (atazanavir, nelfinavir, rilpivirine),  anti-viral drugs (nelfinavir), iron supplements, antibiotic (ampicillin, rifampicin), heart medicine (digoxin) and anti-cancer drug (methotrexate). Let your doctor know if you are taking these medicines.

Drug-Disease Interaction:

 ESOMEPRAZOLE should be not given in patients with Clostridium difficile-associated diarrhea, magnesium and Vitamin B-12 deficiency (increased risk of bone fracture), atrophic gastritis (inflamed lining of the stomach), and acute interstitial nephritis (inflamed cells of the kidney).

Safety Advice

ALCOHOL

Drinking alcohol with ESOMEPRAZOLE may cause dehydration and elevate the level of stomach acid thereby decreasing its efficiency. So try to avoid, limit alcohol, or contact your doctor before intake of ESOMEPRAZOLE.

PREGNANCY

ESOMEPRAZOLE isn't usually recommended during pregnancy as there's no firm evidence it's safe. So, contact a doctor before intake ESOMEPRAZOLE. Your doctor will weigh the benefits and any potential risks before prescribing them to you.

BREAST FEEDING

ESOMEPRAZOLE passes into the breast milk. However, no evidence of risk has been reported. Please consult your doctor before intake ESOMEPRAZOLE. Your doctor will weigh the benefits and any potential risks before prescribing them to you.

DRIVING

In some cases, ESOMEPRAZOLE may cause dizziness, sleepy, or blur vision. If you observe these symptoms do not drive or operate heavy machinery until you feel better.

LIVER

• ESOMEPRAZOLE should be taken with precaution in patients with liver disease.

KIDNEY

Patients with kidney disease should consult a doctor before taking ESOMEPRAZOLE.