PRODUCT DETAILS

About Myphen 500 Tablet

MYCOPHENOLATE MOFETIL belongs to a class of medications called ‘immunosuppressants’ used to prevent the body from rejecting a transplanted organ such as a kidney, heart or liver. Transplant rejection occurs when the recipient’s immune system identifies the transplanted organ as a ‘foreign object’ and attacks it. If it is not treated promptly, it may cause irreversible damage.

MYCOPHENOLATE MOFETIL contains ‘Mycophenolate mofetil’ used in the treatment of organ transplant rejection along with another immunosuppressant and anti-inflammatory agent. It inhibits T and B lymphocytes (a type of white blood cells that attack foreign cells) and suppresses the production of antibodies (identify and kill foreign cells). These effects suppress the immune system so that the transplanted graft is not rejected.

Uses of Myphen 500 Tablet

Transplant rejection prophylaxis

Medicinal Benefits of Myphen 500 Tablet

MYCOPHENOLATE MOFETIL contains ‘Mycophenolate mofetil’ which belongs to the class of ‘immunosuppressants’. It is used to prevent organ transplant rejection. It reduces the activity of the immune system by inhibiting the action of white blood cells (responsible for immune reaction) in the body. It is preferred to use over steroids, which have long-term side-effects.

Directions for Use

MYCOPHENOLATE MOFETIL is available in the following dosage forms: tablet, suspension and injection. Tablet: Your doctor will prescribe the dose and duration based on your health condition. Take MYCOPHENOLATE MOFETIL exactly as prescribed by the doctor. The tablet form of MYCOPHENOLATE MOFETIL should be swallowed as a whole with a glass of water do not break or chew the tablet. Suspension: It is prescribed when you cannot take the tablet dosage form of MYCOPHENOLATE MOFETIL. It is available as a dry powder and mixed with the liquid (mostly boiled and cooled water) up to the mark. Shake the bottle well before each use and take the dose as prescribed. Injection: A healthcare professional will administer the injection form of MYCOPHENOLATE MOFETIL, do not self-administer.

Side Effects of Myphen 500 Tablet

Like all medicines, MYCOPHENOLATE MOFETIL also causes some side-effects, although not everybody gets them. The common side-effects of MYCOPHENOLATE MOFETIL are diarrhoea, vomiting, infections, low white blood cell (WBC) or red blood cell (RBC) count. In general, children and elderly patients are more prone to these side-effects. Inform your doctor right away if any of these side-effects persist or worsen.

Similar Drugs

For informational purposes only. Consult a doctor before taking any medicines.

In-Depth Precautions and Warning

Drug Warnings

Before taking MYCOPHENOLATE MOFETIL, inform your doctor if you have a sign of infection such as a fever or sore throat, have any unexpected bruising or bleeding, have a history of digestive system problems such as a stomach ulcer, are planning to become pregnant, get pregnant while taking MYCOPHENOLATE MOFETIL, and have rare hereditary disorders such as Lesch-Nyhan or Kelley-Seegmiller syndrome (conditions caused by a deficiency of the enzyme hypoxanthine-guanine phosphoribosyl-transferase (HGPRT)). Limit your exposure to sunlight as MYCOPHENOLATE MOFETIL increases the risk of skin cancer. Do not donate blood while taking MYCOPHENOLATE MOFETIL and for at least 60 days after discontinuing the therapy. Men should not donate sperm while taking MYCOPHENOLATE MOFETIL for at least 90 days after discontinuing the therapy. Please do not take any vaccinations (live vaccine) as it will not be much effective. The oral suspension contains aspartame (sweetener and a phenylalanine source), so it should be used with caution in patients with phenylketonuria (a birth defect/congenital disability that causes decreased metabolism of phenylalanine).

Drug Interactions

Drug-Drug Interaction:

MYCOPHENOLATE MOFETIL may interact with an immunosuppressant (azathioprine), antiviral medications (aciclovir and ganciclovir), a medication used to treat tuberculosis (rifampicin), antacids such as proton pump inhibitors, medications used to treat chronic kidney failure such as phosphate binders, and an antibiotic (norfloxacin+metronidazole).

Drug-Disease Interaction:

MYCOPHENOLATE MOFETIL should be used with caution in patients with liver or kidney disease, stomach ulcers, chronic infections and phenylketonuria.

Safety Advice

ALCOHOL

Consumption of alcohol may worsen the condition by increasing the risk of side-effects.

PREGNANCY

MYCOPHENOLATE MOFETIL is a pregnancy category D drug. It causes birth defects in the fetus. So, it is not recommended for use in pregnant women.

BREAST FEEDING

MYCOPHENOLATE MOFETIL is not recommended for breastfeeding mothers as it may get secreted in the breast milk. However, your doctor may prescribe MYCOPHENOLATE MOFETIL if the benefits outweigh the risks.

DRIVING

MYCOPHENOLATE MOFETIL may not affect your ability to drive. However, ask your doctor's advice, whether it is safe to drive based on your health conditions.

LIVER

MYCOPHENOLATE MOFETIL should be used with caution in patients with liver diseases. Dose adjustments may be necessary.

KIDNEY

MYCOPHENOLATE MOFETIL should be used with caution in patients with kidney diseases. Dose adjustments may be necessary.