PRODUCT DETAILS

About Monomet gm 5mg/500mg Tablet

GLIBENCLAMIDE+METFORMIN belongs to the group of medications called ‘antidiabetic agents’ used in the treatment of Type 2 diabetes mellitus. Type 2 diabetes mellitus is a chronic condition in which blood sugar or glucose levels rise. It occurs when the body does not produce enough insulin (metabolizes glucose) or if produced, it cannot function properly in the body.

Uses of Monomet gm 5mg/500mg Tablet

Type 2 Diabetes Mellitus

Medicinal Benefits of Monomet gm 5mg/500mg Tablet

GLIBENCLAMIDE+METFORMIN contains two medicines, namely: Metformin and Glibenclamide. Metformin acts by decreasing liver glucose production and intestinal glucose uptake. Glibenclamide increases the production of insulin by acting on the pancreas. Together GLIBENCLAMIDE+METFORMIN decreases the elevated blood sugar level after the meal along with the recommended diet and exercise. 

Directions for Use

GLIBENCLAMIDE+METFORMIN is available as oral tablets. Tablets are swallowed as a whole with a glass of water. Do not crush, chew or break the tablets. Take the dose as prescribed by your doctor at a fixed time every day. It is recommended to take GLIBENCLAMIDE+METFORMIN with food to prevent hypoglycemia.

Side Effects of Monomet gm 5mg/500mg Tablet

GLIBENCLAMIDE+METFORMIN may cause side-effects such as nausea (feeling sick), vomiting (falling sick), diarrhea, stomach ache and loss of appetite. It may cause vision problems. However, these side-effects are temporary and disappear after a few days. Some patients may also experience a decrease in blood sugar levels (hypoglycemia). Hypoglycemia may result in sweating, dizziness, headache, confusion, feeling hungry, temporary changes in vision, uneasiness, irritability and weakness. In such cases, seek medical attention immediately.

Similar Drugs

For informational purposes only. Consult a doctor before taking any medicines.

In-Depth Precautions and Warning

Drug Warnings

Do not take GLIBENCLAMIDE+METFORMIN if you are allergic to metformin, glibenclamide or any other contents present in it. GLIBENCLAMIDE+METFORMIN may cause ‘lactic acidosis’ (buildup of lactic acid in the blood), characterized by abdominal pain, muscle cramps, vomiting, severe fatigue, and difficulty breathing. It is a life-threatening condition that requires immediate medical attention. Inform your doctor if you have any severe liver or kidney problems as their normal functioning is required to eliminate excess lactic acid from the body.  Do not consume excess alcohol as it increases the risk of lactic acidosis. Inform your doctor if you have any hormonal problems, infectious diseases, or glucose-6-phosphate dehydrogenase - G6PD deficiency (an inherited condition that causes the breakdown of red blood cells).

Drug Interactions

Drug-Drug Interaction:

Do not take the antifungal drug (miconazole) or iodine contrast agents (used for X-ray or scan) while using GLIBENCLAMIDE+METFORMIN. GLIBENCLAMIDE+METFORMIN may interact with medications used to treat high blood pressure like (ritodrine, salbutamol, terbutaline, bosentan), bile acid sequestrants (lower cholesterol levels), drugs used to treat skin inflammation such as corticosteroids, a drug used for diagnosis of adrenocortical insufficiency (tetracosactide), pain killer (phenylbutazone), antifungal drug (fluconazole), a medication used to treat mental illness (chlorpromazine), a medication used to reduce urine production (desmopressin), and medication used to treat endometriosis (danazol).

Drug-Disease Interaction:

GLIBENCLAMIDE+METFORMIN should be used with caution in patients with liver diseases, kidney diseases, hormonal problems, infectious illnesses and heart problems.

Safety Advice

ALCOHOL

Alcohol may increase the risk of side-effects.

PREGNANCY

GLIBENCLAMIDE+METFORMIN should be used with caution only if prescribed by a doctor in pregnant women as it may cause toxic effects to the fetus.

BREAST FEEDING

Breastfeeding mothers should not take GLIBENCLAMIDE+METFORMIN unless prescribed by your doctor.

DRIVING

GLIBENCLAMIDE+METFORMIN may cause vision problems. So, it is not recommended to drive if your vision is blurred while using GLIBENCLAMIDE+METFORMIN.

LIVER

GLIBENCLAMIDE+METFORMIN should be used with caution in patients with liver diseases. Dose adjustments may be necessary.

KIDNEY

GLIBENCLAMIDE+METFORMIN should be used with caution in patients with severe kidney impairment. Consult your doctor for further advice.