PRODUCT DETAILS

About Monocin 450mg Tablet

RIFAMPICIN belongs to the group of medicines called 'anti-tuberculosis drugs' primarily used to treat and prevent tuberculosis (TB). Tuberculosis is an infectious disease that mainly affects the lungs, but it can also spread to other body parts such as kidneys, brain, spine, and bone marrow. RIFAMPICIN does not work against infections caused by the virus, including cold and flu. The bacteria causing tuberculosis (TB) is highly contagious and spread from one person to another via tiny droplets released into the air (through coughs or sneezes).

A RIFAMPICIN consists of a drug called 'rifampicin' which works by inactivating a bacterial protein enzyme (RNA-polymerase) that allows TB bacteria to grow inside the host cell (human).  RIFAMPICIN acts against the bacteria called Mycobacterium tuberculosis, which causes TB (tuberculosis). 

Uses of Monocin 450mg Tablet

Tuberculosis (TB)

Medicinal Benefits of Monocin 450mg Tablet

RIFAMPICIN contains 'Rifampicin' that treats Tuberculosis (TB) by inactivating a bacterial genetic material that allows TB bacteria to make a copy of its protein for further growth inside the host cell (human). RIFAMPICIN is active against gram-positive cocci bacteria like Mycobacteria, Clostridium difficle, and gram-negative bacteria like Neisseria meningitides, N. gonorrhoeae, and Hemophilus influenzae. RIFAMPICIN is also used as a second-line treatment in the treatment of cholestatic pruritus. It also treats leprosy and severe gram-positive bacterial infections (like osteomyelitis, endocarditis, brain abscess, meningitis, and implant infections) in combinations with other antibiotics. 

Directions for Use

Take RIFAMPICIN 30 minutes before food or 2 hours after food empty stomach. Swallow RIFAMPICIN as a whole; do not crush or chew the tablet. The dose and duration of RIFAMPICIN can vary depending upon your condition and the severity of the infection.

Side Effects of Monocin 450mg Tablet

• Drowsiness
• Dizziness 
• Headache 
• Weakness
• Muscle pain
• Heartburn 
• Diarrhea 
• Gas 
• Numbness or tingling sensation 

Similar Drugs

For informational purposes only. Consult a doctor before taking any medicines.

In-Depth Precautions and Warning

Drug-Drug Interaction:

RIFAMPICIN may have interaction with pain killers (acetaminophen, hydrocodone), anti-TB (ethambutol, pyrazinamide) and vitamins (ergocalciferol, cholecalciferol, ascorbic acid), blood thinners (warfarin), Antacids (Pantoprazole, omeprazole), Antibiotics (doxycycline, ciprofloxacin, amoxicillin), cough syrups (diphenhydramine), anti-seizure drugs  ( phenytoin, phenobarbital, Lamotrigine),  azole antifungals (itraconazole, ketoconazole, voriconazole), calcium channel blockers (diltiazem, nimodipine, verapamil).

Safety Advice

ALCOHOL

RIFAMPICIN intake is not recommended with alcohol. A patient is not advised to take alcohol with RIFAMPICIN as it may increase the chances of liver damage.

DRIVING

Caution is advised to be taken by a patient while driving a motor vehicle or doing hazardous work. A patient may experience dizziness, have problems with vision, or have other side effects that could affect his ability to drive while taking this medicine. If this happens, do not drive.

LIVER

Not recommended to be taken in liver patients without a doctor's consultation as RIFAMPICIN has been found to affect liver function with raised ALT enzymes.

KIDNEY

Not recommended for kidney patients without a doctor's consultation. Intake of RIFAMPICIN in these people may result in symptoms like blood in the urine, a change in the amount of urine passed, and feeling drowsy or weak.