PRODUCT DETAILS

About Meplex NT 75mg/10mg Tablet

NORTRIPTYLINE+PREGABALIN is a combination medicine indicated for the management of neuropathic pain associated with diabetic peripheral neuropathy, postherpetic neuralgia, spinal cord injury, etc. Neuropathic pain is a chronic progressive nerve disease which causes nerve pain due to nerve damage or a malfunctioning nervous system.

NORTRIPTYLINE+PREGABALIN is a combination of two drugs: Pregabalin (anti-convulsant) and Nortriptyline (antidepressant). Pregabalin affects the chemicals in the brain that send pain signals across the nervous system. Nortriptyline works by increasing nerve transmitters (serotonin and noradrenaline) in the brain, thereby reducing the pain messages arriving in the brain. Together, NORTRIPTYLINE+PREGABALIN helps to treat neuropathic pain.

Uses of Meplex NT 75mg/10mg Tablet

Neuropathic pain

Medicinal Benefits of Meplex NT 75mg/10mg Tablet

NORTRIPTYLINE+PREGABALIN is a combination of two medicines, namely: Pregabalin and Nortriptyline. NORTRIPTYLINE+PREGABALIN is indicated for the management of neuropathic pain associated with diabetic peripheral neuropathy, postherpetic neuralgia, spinal cord injury, etc. Pregabalin is an anti-convulsant which affects the chemicals in the brain that send pain signals across the nervous system. Nortriptyline is an antidepressant which works by increasing the levels of nerve transmitters (serotonin and noradrenaline) in the brain, thereby reduces the pain messages arriving in the brain. Together, NORTRIPTYLINE+PREGABALIN helps to treat neuropathic pain (pain due to nerve damage).

Directions for Use

Take NORTRIPTYLINE+PREGABALIN with or without food. Swallow NORTRIPTYLINE+PREGABALIN as a whole with a glass of water, do not chew or break the tablet. Based on your medical condition, your doctor will decide how long you need to take NORTRIPTYLINE+PREGABALIN.

Side Effects of Meplex NT 75mg/10mg Tablet

• Dizziness
• Sleepiness
• Nausea
• Blurred vision
• Peripheral oedema (swelling of lower legs and hands)
• Weight gain
• Dry mouth

Similar Drugs

For informational purposes only. Consult a doctor before taking any medicines.

In-Depth Precautions and Warning

Drug Warnings

Do not take NORTRIPTYLINE+PREGABALIN if you are allergic to any of its contents. Inform your doctor before taking NORTRIPTYLINE+PREGABALIN if you have or had heart problems, bipolar syndrome, severe liver disease or if you have taken MAO inhibitors in the last 14days. Consult your doctor before taking cough-cold medicines containing adrenaline-like drugs such as ephedrine, phenylpropanolamine, isoprenaline, noradrenaline or phenylephrine. Please do not stop taking NORTRIPTYLINE+PREGABALIN without consulting your doctor as it could cause withdrawal symptoms. Do not take NORTRIPTYLINE+PREGABALIN if you are pregnant or breastfeeding unless prescribed by the doctor. NORTRIPTYLINE+PREGABALIN causes drowsiness and dizziness, so drive only if you are alert. NORTRIPTYLINE+PREGABALIN should not be given to children as the safety and effectiveness have not been established. Avoid consuming alcohol along with NORTRIPTYLINE+PREGABALIN as it could lead to increased drowsiness and sleepiness. Consult your doctor immediately if you experience suicidal tendencies.

Drug Interactions

Drug-Drug Interaction:

NORTRIPTYLINE+PREGABALIN may have interaction with antidepressants (amitriptyline, duloxetine, mirtazapine, fluoxetine, sertraline, citalopram, escitalopram, bupropion), pain killer (codeine, fentanyl, hydrocodone, morphine, oxycodone, tramadol, acetaminophen), anti-convulsant (gabapentin, phenobarbital, phenytoin, clonazepam, topiramate), anti-anxiety (diazepam, alprazolam), sedative-hypnotics (zolpidem), antihistamine (diphenhydramine, cetirizine), muscle relaxant (cyclobenzaprine), antiemetic (ondansetron).

Drug-Disease Interaction:

NORTRIPTYLINE+PREGABALIN may have interactions with disease conditions such as suicidal tendency, angioedema, creatine kinase elevations, heart problems, depression, fits, pheochromocytoma (tumour of the adrenal gland), bone marrow suppression, tardive dyskinesia (involuntary facial movements), glaucoma, schizophrenia, bipolar disorder, thyroid problems, urinary retention, kidney and liver problems.

Safety Advice

ALCOHOL

Avoid consumption of alcohol while taking NORTRIPTYLINE+PREGABALIN as it may increase drowsiness and sleepiness.

PREGNANCY

Avoid taking NORTRIPTYLINE+PREGABALIN if you are pregnant unless prescribed by a doctor. Please consult your doctor if you have any concerns regarding this, your doctor will prescribe only if the benefits outweigh the risks.

BREAST FEEDING

Consult your doctor before taking NORTRIPTYLINE+PREGABALIN, your doctor will decide whether NORTRIPTYLINE+PREGABALIN can be taken by breastfeeding mothers or not.

DRIVING

NORTRIPTYLINE+PREGABALIN causes drowsiness, sleepiness and blurred vision. Do not drive or operate machinery unless you are alert.

LIVER

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

KIDNEY

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.