PRODUCT DETAILS

About Mefro D 80mg/250mg Tablet

DROTAVERINE+MEFENAMIC ACID is a combination medicine used to treat abdominal pain, muscle pain, migraine headache, functional bowel disorders, dysmenorrhea (menstrual cramps), and heavy bleeding during periods, renal colic pain, and pain after surgery. Pain is a symptom triggered by the nervous system, causing uncomfortable sensations in the body. Muscle spasm is the sudden involuntary contractions of the muscle, which can be painful and uncomfortable.

DROTAVERINE+MEFENAMIC ACID is a combination of two drugs: Drotaverine (anti-spasmodic) and Mefenamic acid (NSAID). Drotaverine works by reducing calcium reuptake by the cells, thereby correcting the body's calcium levels and relieving contractions associated with smooth muscles. Mefenamic acid works by blocking the effect of a chemical messenger in the body, known as cyclo-oxygenase (COX) enzymes that make other chemical prostaglandins (PG). By blocking COX enzymes' effect, lesser PGs are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site. Together, DROTAVERINE+MEFENAMIC ACID helps in relieving pain.

Take DROTAVERINE+MEFENAMIC ACID with food to prevent stomach upset. Swallow DROTAVERINE+MEFENAMIC ACID as a whole with a glass of water; do not chew, or break the tablet. You are advised to take DROTAVERINE+MEFENAMIC ACID for as long as your doctor has prescribed it for you depending on your medical condition. In some cases, you may experience certain common side-effects such as gastrointestinal disturbances, feeling thirsty, nausea, vomiting, diarrhea, dry mouth, rashes, and itching. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

DROTAVERINE+MEFENAMIC ACID can increase your risk of fatal heart attack or stroke. So, if you have had any recent heart surgery, do not take DROTAVERINE+MEFENAMIC ACID. Inform your doctor before taking DROTAVERINE+MEFENAMIC ACID if you have/had asthma, peptic ulcers, porphyria, or bleeding problems. Do not take DROTAVERINE+MEFENAMIC ACID if you are pregnant or breastfeeding unless prescribed. DROTAVERINE+MEFENAMIC ACID may cause dizziness, so drive with caution. DROTAVERINE+MEFENAMIC ACID should not be given to children as safety and efficacy have not been established. Avoid consuming alcohol, and DROTAVERINE+MEFENAMIC ACID as it could lead to increased drowsiness and dizziness; it might also increase stomach bleeding risk. Keep your doctor informed about your health condition and medicines to rule out any side effects.

Uses of Mefro D 80mg/250mg Tablet

Pain relief

Medicinal Benefits of Mefro D 80mg/250mg Tablet

DROTAVERINE+MEFENAMIC ACID is a combination of two drugs, namely: Drotaverine and Mefenamic acid. DROTAVERINE+MEFENAMIC ACID is used to treat abdominal pain, muscle pain, migraine headache, functional bowel disorders, dysmenorrhea (menstrual cramps), heavy bleeding during periods, renal colic pain, and pain after surgery. Drotaverine is an antispasmodic that reduces calcium reuptake by the cells, thereby correcting the calcium levels in the body and relieving contractions associated with smooth muscles. Mefenamic acid is an NSAID that works by blocking the effect of a chemical messenger in the body, known as cyclo-oxygenase (COX) enzymes that make another chemical prostaglandin (PG). These prostaglandins are produced at injury sites and cause pain and swelling. By blocking COX enzymes' effect, lesser PGs are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site. Together, DROTAVERINE+MEFENAMIC ACID helps in relieving pain.

Directions for Use

Take DROTAVERINE+MEFENAMIC ACID with food to prevent stomach upset. Swallow DROTAVERINE+MEFENAMIC ACID as a whole with a glass of water; do not chew, or break the tablet. Based on your medical condition, your doctor will decide how long you need to take DROTAVERINE+MEFENAMIC ACID.

Side Effects of Mefro D 80mg/250mg Tablet

• Gastrointestinal disturbances
• Feeling thirsty
• Nausea
• Vomiting
• Diarrhea
• Dry mouth
• Rashes
• Itching

Similar Drugs

For informational purposes only. Consult a doctor before taking any medicines.

In-Depth Precautions and Warning

Drug Warnings

Do not take DROTAVERINE+MEFENAMIC ACID if you are allergic to any of its contents; if you have severe heart failure, have suffered bleeding problems such as bleeding from the stomach or bowels while taking any pain killers. DROTAVERINE+MEFENAMIC ACID can increase your risk of fatal heart attack or stroke. So, if you have had any recent heart surgery, do not take DROTAVERINE+MEFENAMIC ACID. Inform your doctor before taking DROTAVERINE+MEFENAMIC ACID if you have/had asthma, peptic ulcers, porphyria, bleeding problems, or liver or kidney impairment. Do not take DROTAVERINE+MEFENAMIC ACID if you are pregnant or breastfeeding unless prescribed. DROTAVERINE+MEFENAMIC ACID may cause dizziness, so drive only if you are alert. DROTAVERINE+MEFENAMIC ACID should not be given to children as safety has not been established. Avoid consuming alcohol and DROTAVERINE+MEFENAMIC ACID as it could lead to increased drowsiness and increase the risk of stomach bleeding. Stop taking DROTAVERINE+MEFENAMIC ACID and consult your doctor immediately if you have stomach pain or any signs of bleeding in the intestine or stomach such as blood in stools. Do not take any other NSAIDs for pain relief along with DROTAVERINE+MEFENAMIC ACID unless prescribed.

Drug Interactions

Drug-Drug Interaction:

DROTAVERINE+MEFENAMIC ACID may have interaction with pain killers (aspirin, ibuprofen, celecoxib), anticoagulants (warfarin), anti-Parkinson's (levodopa), immunosuppressant (cyclosporine, tacrolimus), anti-gout (probenecid), anti-depressant (duloxetine, lithium, fluoxetine, sertraline), cardiac glycosides (digoxin), anti-rheumatoid (methotrexate), anti-HIV (zidovudine), and antiprogestational steroids (mifepristone).

Drug-Disease Interaction:

DROTAVERINE+MEFENAMIC ACID may have interactions with peptic ulcers, bleeding disorders, low blood pressure, diabetes, Crohn's disease, inflammatory bowel disease, and heart, kidney, and liver problems.

Safety Advice

ALCOHOL

Avoid consumption of alcohol while taking DROTAVERINE+MEFENAMIC ACID as it may increase drowsiness. It can also increase the risk of stomach bleeding.

PREGNANCY

Please consult your doctor if you are pregnant or if you have any concerns regarding this, your doctor will prescribe only if the benefits outweigh the risks.

BREAST FEEDING

Consult your doctor before taking DROTAVERINE+MEFENAMIC ACID if you are breastfeeding. Your doctor will prescribe only if the benefits outweigh the risks.

DRIVING

DROTAVERINE+MEFENAMIC ACID usually causes drowsiness, and it affects driving ability.

LIVER

Please consult your doctor if you have a liver impairment or any concerns regarding this. Your doctor will prescribe only if the benefits outweigh the risks.

KIDNEY

Please consult your doctor if you have kidney impairment or any concerns regarding this. Your doctor will prescribe only if the benefits outweigh the risks.