PRODUCT DETAILS

About Mansazol D 10mg/40mg Capsule

DOMPERIDONE+PANTOPRAZOLE is composed of two medicines, namely: Domperidone and Pantoprazole. Domperidone is a prokinetic and anti-nausea agent that helps to treat indigestion and stomach pain. On the other hand, Pantoprazole is a proton pump inhibitor that reduces the excess stomach acid formation by blocking the actions of an enzyme (H+/K+ ATPase or gastric proton pump). DOMPERIDONE+PANTOPRAZOLE is a widely used medicine to treat peptic ulcers and gastroesophageal reflux disease (GERD). DOMPERIDONE+PANTOPRAZOLE prevents the release of stomach acid and relieves symptoms of food pipe lining inflammation (esophagitis), gastroesophageal reflux disease (GERD), or heartburn.

Domperidone works by increasing the movement of food through the stomach and the digestive tract more quickly and in this way reduces the feeling of bloating, or fullness and indigestion. On the other hand, it effectively blocks the action of a vomiting center (chemoreceptor trigger zone - CTZ) located in your brain, which is responsible for inducing the feeling of nausea and vomiting. Pantoprazole helps in reducing the stomach acid by blocking the actions of an enzyme (H+/K+ ATPase or gastric proton pump). This proton pump lies in the cells of the stomach wall responsible for the release of gastric acid secretion damaging tissues in the food pipe, stomach, and duodenum.

DOMPERIDONE+PANTOPRAZOLE can be prescribed to adults and children aged 12 years and over. It is better to take DOMPERIDONE+PANTOPRAZOLE an hour before a meal. DOMPERIDONE+PANTOPRAZOLE should be swallowed whole with a glass of water. Do not chew, crush, or break it. Avoid intake of DOMPERIDONE+PANTOPRAZOLE for more than four weeks of duration without consulting the doctor. You can increase the efficacy of DOMPERIDONE+PANTOPRAZOLE by taking a small meal or snacks frequently. Try to avoid caffeine-containing beverages (coffee, tea), spicy/deep-fried/processed foods, carbonated drinks, and acidic foods like citrus fruits/vegetables (tomatoes).

Like all medicines, DOMPERIDONE+PANTOPRAZOLE may cause side effects, although not everybody gets them. The most common side effects of DOMPERIDONE+PANTOPRAZOLE are diarrhea, stomach pain, flatulence (gas), dryness in the mouth, dizziness, and headache. Everyone doesn't need to experience the above side effects. In case of any discomfort, speak with your doctor. Prolonged intake of Pantoprazole is associated with a low level of Vitamin B12 and low magnesium. Hence yearly test of Vitamin B12 and magnesium is required if you are taking DOMPERIDONE+PANTOPRAZOLE for the long term. The use of DOMPERIDONE+PANTOPRAZOLE is contraindicated in people with lupus (autoimmune inflammatory disease).

Uses of Mansazol D 10mg/40mg Capsule

Gastroesophageal reflux disease (GERD), Heartburn due to hyperacidity, Inflammation of food pipe (esophagitis), Peptic ulcer

Medicinal Benefits of Mansazol D 10mg/40mg Capsule

DOMPERIDONE+PANTOPRAZOLE plays a vital role in preventing nausea, vomiting, stomach upset, stomach pain, peptic ulcer, and other conditions due to hyperacidity or acid reflux. Pantoprazole prevents the proton pump gate from producing an excessive amount of stomach acid. While Domperidone stops nausea (feeling sick) and vomiting (being sick) blocking messages between parts of your brain called the chemoreceptor trigger zone (CTZ) and the vomiting center.

Directions for Use

It is better to take DOMPERIDONE+PANTOPRAZOLE an hour before a meal. DOMPERIDONE+PANTOPRAZOLE should be swallowed whole with a glass of water. Do not chew, crush, or break it. Do not take DOMPERIDONE+PANTOPRAZOLE for more than 4 weeks of duration without consulting the doctor.

Side Effects of Mansazol D 10mg/40mg Capsule

Most of the side effects of DOMPERIDONE+PANTOPRAZOLE do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor. Some common side effects of DOMPERIDONE+PANTOPRAZOLE are headache, diarrhea, nausea, abdominal pain, vomiting, flatulence, dizziness, and arthralgia (joint pain). Very rarely, it may cause swelling of the tongue and/or throat, difficulty in swallowing, difficulties in breathing, allergic facial swelling, severe dizziness with a very fast heartbeat, and heavy sweating. blistering of the skin, acute kidney injury, yellowing of the skin, fever, rash, and enlarged kidneys sometimes with painful urination, and lower back pain (serious inflammation of the kidneys), possibly leading to kidney failure. This requires immediate medical attention.

Similar Drugs

For informational purposes only. Consult a doctor before taking any medicines.

In-Depth Precautions and Warning

Drug Warnings

You should avoid taking DOMPERIDONE+PANTOPRAZOLE if you are allergic to DOMPERIDONE+PANTOPRAZOLE or proton pump inhibitors, have gastric cancer, liver disease, low magnesium level (osteoporosis), low vitamin B12, pregnant or planning for pregnancy, and breastfeeding mothers. DOMPERIDONE+PANTOPRAZOLE may interact with a blood thinner (warfarin), antifungal (ketoconazole), anti-HIV drug (atazanavir, nelfinavir), iron supplements, ampicillin antibiotic, anti-cancer drug (methotrexate). Let your doctor know if you are taking these medicines. Prolonged intake of DOMPERIDONE+PANTOPRAZOLE may cause lupus erythematosus (an inflammatory condition in which the immune system attacks its own tissues), Vitamin B12, and magnesium deficiency. Intake of DOMPERIDONE+PANTOPRAZOLE may mask the symptom of gastric cancer, so if you have any severe stomach pain or gastric bleeding (blood in mucous or stool) immediately consult the doctor. 

Drug Interactions

Drug-Drug Interaction:

DOMPERIDONE+PANTOPRAZOLE may interact with a blood thinner (clopidogrel, warfarin), antifungal (ketoconazole, voriconazole, itraconazole, posaconazole), anti-HIV drug (atazanavir, nelfinavir), iron supplements, antibiotic (ampicillin, rifampicin), heart medicine (digoxin) and anti-cancer drug (methotrexate). Let your doctor know if you are taking these medicines.

Drug-Disease Interaction:

DOMPERIDONE+PANTOPRAZOLE should be not given in patients with C. difficile-induced colitis, liver disease, bone fractures, low Vitamin B12 (anemia), and low magnesium (hypomagnesemia).

Safety Advice

ALCOHOL

It is best to avoid alcohol while taking medication.

PREGNANCY

If you are pregnant, think you may be pregnant, or are planning to have a baby, ask your doctor for advice before taking this medicine. You should use this medicine only if your doctor considers the benefit for you greater than the potential risk for your unborn child or baby.

BREAST FEEDING

The name is not recommended during breastfeeding. However, your doctor may prescribe it for you during breastfeeding if he/she feels that the benefit to you outweighs the risk. You should not take $ name without a doctor's advice.

DRIVING

Drive only if you are physically stable and mentally focussed, If you experience drowsiness after taking DOMPERIDONE+PANTOPRAZOLE you should not drive or operate any machinery or vehicles.

LIVER

In patients with severe liver impairment, the liver enzymes should be monitored regularly during treatment with pantoprazole, particularly during long-term use

KIDNEY

If u have or had a history or evidence of any kidney-related diseases, please consult the doctor before taking the DOMPERIDONE+PANTOPRAZOLE.