PRODUCT DETAILS

About Madotine 20mg Tablet

PAROXETINE belongs to a group of medicines called antidepressants used to treat a major depressive disorder, obsessive-compulsive disorder (OCD), panic disorder, social anxiety disorder, post-traumatic stress disorder and premenstrual dysphoria disorder and generalised anxiety disorder. Depression is a mood disorder characterised by sadness, unhappiness, anger, hopelessness or loss that interferes with a person’s daily activities.

PAROXETINE contains ‘Paroxetine’ which is a selective serotonin reuptake inhibitor. It works by inhibiting serotonin's reuptake, a mood-enhancing chemical messenger in the brain that communicates between brain cells. This helps increase serotonin concentrations in the nerve synapse, thereby regulating mood and treating depression and anxiety disorders.

Take PAROXETINE as prescribed. You are advised to take PAROXETINE for as long as your doctor has prescribed it for you depending on your medical condition and response to the treatment. In some cases, you may experience certain common side-effects such as insomnia (difficulty sleeping), dizziness, headache, diarrhoea, nausea, fatigue, dry mouth, loss of appetite, pin and sexual disturbances. You are advised to talk to your doctor if you experience these side-effects persistently.

Uses of Madotine 20mg Tablet

Major depressive disorder, obsessive-compulsive disorder (OCD), panic disorder, social anxiety disorder, post-traumatic stress disorder, premenstrual dysphoric disorder, and generalised anxiety disorder.

Medicinal Benefits of Madotine 20mg Tablet

PAROXETINE belongs to a group of antidepressant medicines called selective serotonin reuptake inhibitors. PAROXETINE is used to treat major depressive disorder, obsessive-compulsive disorder (OCD), panic disorder, social anxiety disorder, post-traumatic stress disorder, premenstrual dysphoric disorder, and generalised anxiety disorder. PAROXETINE works by inhibiting serotonin's reuptake by nerves, a mood-enhancing chemical messenger in the brain that communicates between brain cells. This helps increase serotonin concentrations in the nerve synapse, thereby regulating mood and treating depression and anxiety disorders. PAROXETINE has fewer unwanted side-effects than older antidepressants and helps people recover from depression.

Directions for Use

Take PAROXETINE in the morning with food to prevent stomach upset. Your doctor will decide for how long you need to take PAROXETINE based on your medical condition and response to treatment. Take PAROXETINE exactly as prescribed by the doctor. PAROXETINE available in both tablet and liquid dosage forms Tablet: Swallow PAROXETINE as a whole with a glass of water; do not chew, or crush the tablet. Liquid: Take the prescribed dose/quantity using the measuring cup provided by the pack; shake the bottle well before use.

Side Effects of Madotine 20mg Tablet

• Insomnia (difficulty sleeping)
• Headache
• Diarrhoea
• Nausea
• Fatigue
• Dry mouth
• Loss of appetite
• Sexual disturbances

Similar Drugs

For informational purposes only. Consult a doctor before taking any medicines.

In-Depth Precautions and Warning

Drug Warnings

Do not take PAROXETINE if you are allergic to any of its contents; if you are taking monoamine oxidase inhibitors (MAOI) or have taken them in the last 14days, or if you are taking antipsychotic medicines such as thioridazine or pimozide. Consult your doctor immediately if you have suicidal thoughts such as killing or harming yourself. Inform your doctor before taking PAROXETINE if you have/had epilepsy, mania, diabetes, low sodium levels in blood, glaucoma, or undergoing treatment for severe depression called electro-convulsive therapy. Do not take PAROXETINE if you are pregnant as it may cause harm to the foetus. Consult your doctor before taking PAROXETINE if you are breastfeeding. Avoid driving or operating machinery as PAROXETINE may cause dizziness, confusion, sleepiness and blurred vision. PAROXETINE is not recommended for children below 18years as the safety and effectiveness have not been established. Avoid consumption of alcohol while taking PAROXETINE as it may make your symptoms or side-effects worse.

Drug Interactions

Drug-Drug Interaction:

PAROXETINE may have interaction with blood thinners (warfarin, clopidogrel), anti-psychotics (perphenazine, thioridazine, clozapine. Lithium, risperidone), antidepressants (clomipramine, moclobemide, methylthioninium chloride/methylene blue, nortriptyline, desipramine), NSAID’s (acetylsalicylic acid, ibuprofen, celecoxib, etodolac, diclofenac, meloxicam, tramadol, pethidine), anti-cancer (tamoxifen), anti-migraine (sumatriptan), dietary supplement (tryptophan), opioid analgesics (fentanyl), anti-HIV (ritonavir, fosamprenavir), anti-convulsant (phenobarbital, phenytoin, carbamazepine), anti-arrhythmic (propafenone, flecainide), anti-hypertensive (metoprolol), anti-TB (rifampicin), antibiotic (linezolid), statin (pravastatin), neuromuscular blocker (mivacurium, suxamethonium), norepinephrine reuptake inhibitor (Atomoxetine), and anticholinergic medication (Procyclidine).

Drug-Disease Interaction:

PAROXETINE may have interactions with disease conditions such as glaucoma, diabetes, epilepsy, mania, bleeding problems, hyponatremia (low sodium levels), heart, liver and kidney dysfunction.

Safety Advice

ALCOHOL

Avoid consumption of alcohol while taking PAROXETINE as it may make your symptoms or side-effects worse.

PREGNANCY

PAROXETINE belongs to pregnancy category D. It is not recommended to take PAROXETINE if you are pregnant or planning for pregnancy as PAROXETINE might cause foetal harm.

BREAST FEEDING

PAROXETINE may pass into breastmilk. Consult your doctor before taking PAROXETINE; your doctor will decide whether PAROXETINE can be taken by breastfeeding mothers or not.

DRIVING

PAROXETINE may cause dizziness, confusion, sleepiness and blurred vision. Do not drive or operate machinery if you experience these symptoms.

LIVER

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

KIDNEY

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.