PRODUCT DETAILS

About Isocrate 20mg Tablet

ISOSORBIDE DINITRATE belongs to the class of blood pressure-lowering medications called ‘nitrate vasodilators’ used in the prevention of angina (heart-related chest pain) or heart failure. Angina pectoris (angina) is the chest pain occurring due to reduced blood flow to the heart (coronary artery disease). It occurs when the blood vessels supplying the heart are blocked or narrowed.

Uses of Isocrate 20mg Tablet

Angina (heart related chest pain)

Medicinal Benefits of Isocrate 20mg Tablet

ISOSORBIDE DINITRATE contains ‘isosorbide dinitrate’ which is a ‘nitrate’ and a vasodilator. It acts by dilating and relaxing the constricted blood vessels due to increased blood pressure (hypertension). This effect helps in improving the blood and oxygen supply to the heart, thus decreasing the risk of angina or heart-related chest pain. Thus, ISOSORBIDE DINITRATE prevents the risk of chest pain in heart conditions like coronary artery disease. 

Directions for Use

ISOSORBIDE DINITRATE is available in the form of tablets. The dose and duration of the medication are prescribed by your doctor. Do not increase or decrease the dose without the doctor’s advice. Swallow the tablet as a whole with a glass of water. Do not chew, crush or break it. Try to take the tablets at a fixed time every day.

Side Effects of Isocrate 20mg Tablet

Like all medicines, ISOSORBIDE DINITRATE can also cause side-effects, although not everybody gets them. The most common side-effect of ISOSORBIDE DINITRATE is headache, which is mostly seen during the initial days of therapy. It can also cause flushing (redness of the skin, especially the face), low blood pressure, and dizziness. These side-effects are mild and go away without requiring any treatment.

Similar Drugs

For informational purposes only. Consult a doctor before taking any medicines.

In-Depth Precautions and Warning

Drug Warnings

Do not take ISOSORBIDE DINITRATE if you are allergic to ‘isosorbide dinitrate’ or its contents. Do not take it if you have severe low blood pressure, bleeding or increased pressure in the brain, severe dehydration, heart valve problems, inflammation of the heart wall, high blood pressure due to long-term lung disease, and severe anaemia. Before taking ISOSORBIDE DINITRATE, inform your doctor if you have glaucoma (increased pressure in the eye), glucose 6 phosphate dehydrogenase deficiency (a type of anaemia), underactive thyroid (hypothyroidism), kidney or liver problems, head injury, hypothermia (low body temperature), or intolerance to some sugars. This medicine should not be used with medicines used for erectile dysfunction like sildenafil or tadalafil. Inform your doctor if you are pregnant or breastfeeding.

Drug Interactions

Drug-Drug Interaction:

 ISOSORBIDE DINITRATE should not be used with organic nitrate drugs used to treat erectile dysfunction (sildenafil, vardenafil, tadalafil, and avanafil) and medicine used to treat pulmonary hypertension (riociguat), medicines to treat high blood pressure (norepinephrine), phenothiazines, and antiallergic medications.

Drug-Disease Interaction:

 ISOSORBIDE DINITRATE use is contraindicated in conditions such as acute myocardial infarction or congestive heart failure, severe hypotension (low blood pressure), severe anemia, bleeding in the brain, and severe dehydration

Safety Advice

ALCOHOL

Alcohol may worsen the condition by increasing the risk of side-effects. So, do not take alcohol

PREGNANCY

ISOSORBIDE DINITRATE is a category C medicine and may cause harm to the fetus. It should be used in pregnant women if clinically needed and when benefits outweigh the risks.

BREAST FEEDING

ISOSORBIDE DINITRATE should be used with caution in breastfeeding mothers

DRIVING

ISOSORBIDE DINITRATE may cause dizziness and affect your ability to drive. So, avoid driving or operating heavy machinery while using ISOSORBIDE DINITRATE.

LIVER

ISOSORBIDE DINITRATE should be used with caution in patients with liver diseases. Dose adjustments may be required in severe liver disease patient.

KIDNEY

ISOSORBIDE DINITRATE should be used with caution in patients with kidney diseases. Dose adjustments may be required.