PRODUCT DETAILS

About Insulatard 100IU/ml Solution for Injection

INSULIN ISOPHANE contains human insulin, used to improve blood sugar control in adults and children with type 1 and type 2 diabetes mellitus. It maintains blood sugar levels in both adults and children. Diabetes mellitus is a condition that affects the way your body processes glucose. In Diabetes Mellitus Type 1, the body does not make enough insulin to control blood sugar levels. In Diabetes Mellitus type 2, either the body stops producing enough insulin (the hormone which helps to decrease sugar levels in the blood) or there is resistance to the action of insulin. As a result, insulin is produced in large amounts but it is not able to act on the organs of the body.

INSULIN ISOPHANE works by ensuring rapid and consistent sugar control. INSULIN ISOPHANE is a fast-acting type of insulin which helps to decrease blood sugar levels after the intake of meals. It prevents the chances of developing serious complications of diabetes. It facilitates the reuptake of sugar in muscle and fat cells and thus, suppresses the production of sugar in the liver.

Uses of Insulatard 100IU/ml Solution for Injection

Type 1 diabetes mellitus, Type 2 diabetes mellitus

Medicinal Benefits of Insulatard 100IU/ml Solution for Injection

When you take INSULIN ISOPHANE, it works by ensuring rapid and consistent sugar control. It facilitates the reuptake of sugar in muscle and fat cells and thus, suppresses the production of sugar in the liver.  It helps to decrease blood sugar levels after the intake of meals. It prevents the chances of developing serious complications of diabetes. Besides this, INSULIN ISOPHANE can be safely prescribed to the diabetic mother in the pregnancy as well as lactation stage. INSULIN ISOPHANE helps in improving the glycaemic control which in turn decreases the risk of progression of complications of diabetes like damage of retina (retinopathy), damage of kidney (nephropathy), damage of nerve cells (neuropathy), delayed wound healing, diabetic foot ulcer and others.

Directions for Use

INSULIN ISOPHANE should never be administered intravenously or in the vein. It is administered subcutaneously in the abdomen or thigh region. However subcutaneous injection of INSULIN ISOPHANE in the abdomen region ensures faster absorption compared to other injection sites. INSULIN ISOPHANE is usually given once or twice daily when both rapid and prolonged effect of insulin is desired. An injection of INSULIN ISOPHANE should be followed within 30 minutes by a meal or snack containing sugar/glucose (carbohydrates). If you are not well trained to self-administer INSULIN ISOPHANE, ask healthcare professional to administer it. Procedure for self-injecting insulin: • You should wash your hand first before injecting insulin. • Then roll the insulin bottle and wipe the bottle top. • Now pull the plunger of syringe down to appropriate number of units your doctor has prescribed. • Push the needle into the bottle and push syringe plunger down. • Now once again pull the plunger down to appropriate number of units as prescribed by the doctor. • Pick the injection site and wipe it with alcohol swab. Now, pinch up skin and push the needle into skin and then push the plunger in. • The needle should be kept under the skin for at least 6 seconds to make sure the entire dose is injected. • After injecting the insulin pull out the needle and dispose the syringe safely. And then you can have meal or snack.

Side Effects of Insulatard 100IU/ml Solution for Injection

Like all medicines, this medicine can cause side effects, although not everybody gets them. The following side effects may happen with INSULIN ISOPHANE: Hypoglycemia - It is a frequently occurring undesirable effect of insulin therapy. Symptoms of hypoglycemia usually occur suddenly. They may include cold sweat, cool pale skin, nervousness or tremor, anxious feeling, unusual tiredness or weakness, confusion, difficulty in concentration, drowsiness, excessive hunger, temporary vision changes, headache, nausea and palpitation. Severe hypoglycemia may lead to unconsciousness and may result in temporary or permanent impairment of brain function or even death. Serious side effects include Generalized hypersensitivity reactions include generalized skin rash, itching, sweating, gastrointestinal upset, angioneurotic edema, difficulties in breathing, palpitation and reduction in blood pressure. These are potentially life-threatening. It is not necessary for everyone to experience the above side effects. Please consult your doctor immediately if you experience worsening of any of the side-effects.

Similar Drugs

For informational purposes only. Consult a doctor before taking any medicines.

In-Depth Precautions and Warning

Drug Warnings

INSULIN ISOPHANE is for subcutaneous use only and should never be administered intravenously (IV) or in the veins. If you are changing the brand of insulin, it should be done under strict medical supervision. Cases of heart failure have been reported when pioglitazone was used with insulin especially in patients who are at high risk of cardiac heart failure. The first symptoms of hyperglycaemia (high blood sugar level) may include symptoms like excessive thirst, dry mouth, increased frequency of urination, nausea, vomiting, drowsiness, flushed dry skin, loss of appetite and acetone odour of breath. You should closely monitor these symptoms. Symptoms like heart failure, weight gain and oedema (fluid deposition in tissue) should not be overruled. You are recommended not to consume alcohol as it may increase or decrease your blood glucose level. Care should be taken when you are traveling across more than 2 time zones. Your doctor may adjust your insulin schedule. INSULIN ISOPHANE may decrease level of potassium leading to state of hypokalaemia that, if left untreated, may lead to respiratory paralysis, irregular heartbeat rhythm, coma and even death. Do not take this medicine if you have any low blood glucose levels, kidney, liver, or heart problems, or problems with alcohol or other prescription recreational drugs.

Drug Interactions

Drug-Drug Interaction:

 This medicine may have an interaction with anti-depressants (phenelzine, iproniazid, isocarboxazid, nialamide, imipramine, desipramine, tranylcypromine, moclobemide), anti Parkinson’s drug (selegiline), antibiotic (linezolid), (lithium, tryptophan), migraines drug (sumatriptan), pain killer (tramadol), anti-ulcer (cimetidine, lansoprazole, omeprazole), anti-fungal (fluconazole), anti-stroke pills (ticlopidine), blood-thinners (warfarin, dipyridamole, and phenprocoumon), antimalarial (mefloquine), heart-related drug (flecainide, propafenone), and medicines that decrease blood levels of potassium or magnesium, as these increase the risk of life-threatening heart rhythm disorder. Besides this, the use of oral antidiabetic pills like pramlintide and antibiotics (pentamidine) may cause hypoglycaemia (low blood sugar level).

Drug-Disease Interaction:

 INSULIN ISOPHANE should not be given to patients with kidney disease, liver disease, low potassium level (hypokalaemia) and low blood sugar/glucose level (hypoglycaemia).

Safety Advice

ALCOHOL

You are recommended not to consume alcohol along with INSULIN ISOPHANE to avoid unpleasant side-effects. Alcohol may either decrease or increase the blood sugar level which can be fatal.

PREGNANCY

• Please inform your doctor if you are pregnant as a dose adjustment may be required. The amount of insulin you need usually falls during the first three months of pregnancy and increases for the remaining six months.

  •  

BREAST FEEDING

Please inform your doctor if you are breastfeeding as a dose adjustment may be required.

DRIVING

Drive with caution, INSULIN ISOPHANE usually causes drowsiness and affects driving ability. Your ability to concentrate and react may be reduced if you have hypoglycaemia (low blood sugar).

LIVER

INSULIN ISOPHANE to be taken with caution, especially if you have a history of liver diseases/conditions. The dose may have to be adjusted by your doctor.

KIDNEY

INSULIN ISOPHANE to be taken with caution, especially if you have a history of kidney diseases/conditions. The dose may have to be adjusted by your doctor.