PRODUCT DETAILS

About Imiz 2 mg/25 mg Tablet

DIAZEPAM+IMIPRAMINE belongs to the class of medications called ‘antidepressants’ used in the treatment of depression. Depression is a mood disorder that affects a person's daily life described as feelings of sadness, loss, or anger. These symptoms may interfere with your daily activities and affect your quality of life.

DIAZEPAM+IMIPRAMINE contains Imipramine and Diazepam. Imipramine is a tricyclic antidepressant. It works by increasing serotonin and noradrenalin levels, chemicals present in the brain responsible for energy, mood, and behavior. Diazepam is a benzodiazepine. It increases the levels of chemicals in the brain that produce a calming effect. Together, DIAZEPAM+IMIPRAMINE can effectively reduce the symptoms of depression.

You should take this medicine exactly as prescribed by the doctor. DIAZEPAM+IMIPRAMINE may cause side effects such as drowsiness, fatigue (extreme tiredness), confusion, loss of coordination of body movements (ataxia), dryness in the mouth, constipation, difficulty in urination, difficulty passing urine, low blood pressure, decrease in sexual function, dilation of the pupil of the eye, vision problems, loss of appetite, and increased heart rate. These side effects usually don’t require medical attention. However, if any of these side effects persist or get worse, inform your doctor immediately.

It is not recommended to take DIAZEPAM+IMIPRAMINE if you are allergic to any contents of it. Do not take DIAZEPAM+IMIPRAMINE if you have severe liver disease, heart disease, mania (exaggerated behavior or hyperactivity), porphyria (an inherited blood disorder), difficulty passing urine, glaucoma (increased pressure inside the eye), severe breathing problems, phobia (a fear of particular object), myasthenia gravis (a condition in which muscles weaken), and sleep apnoea (a sleep disorder). Inform your doctor if you are pregnant or breastfeeding. It is not recommended for use in children below 6 years of age. In children and young adults below 25 years, this medicine should be used with caution as it may increase suicidal tendencies and worsen depression. It should be used with caution in elderly patients. Alcohol consumption may increase the risk of side effects. DIAZEPAM+IMIPRAMINE may cause drowsiness or blurred vision, so do not drive or operate heavy machinery if you are not fully alert.

Uses of Imiz 2 mg/25 mg Tablet

Depression

Medicinal Benefits of Imiz 2 mg/25 mg Tablet

DIAZEPAM+IMIPRAMINE is used to treat depression. It decreases the number of episodes of depression and also reduces the duration of each depressive episode. It improves mood, behavior, and sleep and decreases anxiety. This medicine is prescribed for longer durations as it may take several weeks to improve your overall condition. DIAZEPAM+IMIPRAMINE is highly effective if taken regularly as per the doctor’s advice.

Directions for Use

DIAZEPAM+IMIPRAMINE is available in the form of tablets. Tablets are swallowed as a whole with a glass of water. Do not break, chew, or crush the tablet. The exact dose and duration are given by the doctor based on your health condition.

Side Effects of Imiz 2 mg/25 mg Tablet

• Drowsiness
• Fatigue (extreme tiredness)
• Confusion
• Headache
• Dizziness
• Slurred speech
• Loss of coordination of body movements (ataxia)
• Dryness in mouth
• Constipation
• Difficulty passing urine
• Low blood pressure
• Disturbances in sexual function
• Dilation of the pupil of the eye
• Vision problems
• Loss of appetite
• Increased heart rate
• Changes in libido
• Weight increase

Similar Drugs

For informational purposes only. Consult a doctor before taking any medicines.

In-Depth Precautions and Warning

Drug Warnings

It is not recommended to take monoamine oxidase inhibitors (MAOI) and DIAZEPAM+IMIPRAMINE simultaneously. You should wait for at least 14 days after discontinuing MAOI before using DIAZEPAM+IMIPRAMINE. Before taking DIAZEPAM+IMIPRAMINE, inform your doctor if you have any mental illness, personality disorder, are withdrawing from alcohol or any other medicines, enlarged prostate gland, overactive thyroid, fits, brain damage, poor blood circulation, severe kidney disease, tumors in the adrenal gland, panic attacks, long-term constipation, low levels of albumin, and a habit of smoke. Inform your doctor if you have suicidal thoughts as DIAZEPAM+IMIPRAMINE may worsen suicidal tendencies, especially in young adults. While taking DIAZEPAM+IMIPRAMINE, inform your doctor if you experience agitation, restlessness, nightmares, and hallucinations as this medicine may cause these side effects, especially in children and the elderly. DIAZEPAM+IMIPRAMINE may cause total or partial memory loss when taken in high doses. DIAZEPAM+IMIPRAMINE may cause dependence, so it should be used for the shortest time possible in patients with a history of alcohol or drug abuse. After a few weeks of treatment, if the tablets are not working for you, inform your doctor immediately, as it can be a sign of tolerance. DIAZEPAM+IMIPRAMINE should not be used in combination with an opioid pain killer (buprenorphine). Concomitant use of these drugs may lead to serotonin syndrome (a life-threatening condition that causes high blood pressure and fast heart rate).

Drug Interactions

Drug-Drug Interaction:

DIAZEPAM+IMIPRAMINE may interact with an opioid pain killer (buprenorphine), a medicine used to treat sleep problems (sodium oxybate), other antidepressants (fluvoxamine, fluoxetine, phenelzine, moclobemide, and Hypericum perforatum), antipsychotics (clozapine), medicines used to treat allergies, general anesthetics, medicines used to induce sleep (alprazolam), antibiotics (erythromycin and rifampicin), medicines used to relax muscles (suxamethonium and tubocurarin), strong pain killer (morphine), medicines used to treat fits or mental disorders (phenobarbital), medicines used to treat high blood pressure, antacids (cimetidine, omeprazole, and esomeprazole), a medicine used to treat alcohol addiction (disulfiram), medicines used to treat fits (phenytoin, carbamazepine, and sodium valproate), medicine used to treat asthma (theophylline), antivirals (atazanavir, ritonavir, efavirenz, indinavir, and zidovudine, etc.), antitubercular (isoniazid), oral contraceptives, steroid medicines, anesthetic (ketamine), medicines to treat nausea and vomiting (nabilone), and medicines used to treat heart conditions (diltiazem, verapamil, and quinidine, etc.).

Drug-Disease Interaction:

DIAZEPAM+IMIPRAMINE should not be used in patients with severe liver disease, heart disease, mania (exaggerated behavior or hyperactivity), porphyria (an inherited blood disorder), difficulty passing urine, glaucoma (increased pressure inside the eye), severe breathing problems, phobia (a fear of particular object), myasthenia gravis (a condition in which muscles weaken), and sleep apnoea (a sleep disorder).

Safety Advice

ALCOHOL

Do not take alcohol while using DIAZEPAM+IMIPRAMINE as it can cause excessive drowsiness.

PREGNANCY

DIAZEPAM+IMIPRAMINE is not recommended for pregnant women as it may cause harmful effects on the unborn baby.

BREAST FEEDING

DIAZEPAM+IMIPRAMINE may pass into breastmilk and cause harmful effects on the nursing baby. So, it is not recommended to use in breastfeeding mothers.

DRIVING

DIAZEPAM+IMIPRAMINE may cause drowsiness and blurred vision, so do not drive or operate heavy machinery while using this medicine.

LIVER

DIAZEPAM+IMIPRAMINE should not be used in patients with severe liver diseases. It should be used with caution in patients with mild to moderate liver diseases, and the dose may have to be adjusted by your doctor.

KIDNEY

DIAZEPAM+IMIPRAMINE should be used with caution in patients with kidney diseases. The dose may have to be adjusted by your doctor.