PRODUCT DETAILS

About Glycinorm Total 60 Tablet SR

GLICLAZIDE+METFORMIN+PIOGLITAZONE is a combination of three antidiabetic medicines, namely: Gliclazide, Metformin and pioglitazone. Type 2 diabetes is a chronic or lifelong condition that affects the way your body processes glucose. People with type 2 diabetes either do not produce enough insulin or if at all the insulin is produced, it is unable to perform its function in the body (insulin resistance). Due to this, the blood glucose level increases and symptoms such as frequent urination, increased thirst and increased hunger start. It can lead to serious complications like skin infection, eye problems (retinopathy), nerve damage (neuropathy), diabetic foot (foot ulcer), kidney disease (nephropathy), high blood pressure, and even stroke.

Uses of Glycinorm Total 60 Tablet SR

Type 2 Diabetes Mellitus

Medicinal Benefits of Glycinorm Total 60 Tablet SR

GLICLAZIDE+METFORMIN+PIOGLITAZONE contains three medicines, namely: Gliclazide, Metformin, and Pioglitazone. Gliclazide increases the production of insulin by acting on the pancreas. Metformin acts by decreasing liver glucose production and intestinal glucose uptake. Pioglitazone works by decreasing the amount of glucose released by the liver and improving the sensitivity of tissues of muscles and fats towards insulin effects. Together GLICLAZIDE+METFORMIN+PIOGLITAZONE decreases the elevated blood sugar level after the meal along with the recommended diet and exercise. GLICLAZIDE+METFORMIN+PIOGLITAZONE also helps to prevent serious complications of diabetes such as kidney damage (diabetic nephropathy), blindness (diabetic retinopathy), loss of sensation in your hands and feet (diabetic neuropathy) or even loss of the foot. GLICLAZIDE+METFORMIN+PIOGLITAZONE also helps to reduce your chance of having a heart attack or stroke. Being a combination of two drugs, it reduces the need to take multiple pills and hence makes it easier to remember to take the drugs.

Directions for Use

GLICLAZIDE+METFORMIN+PIOGLITAZONE is available as oral tablets. Tablets: Tablets are swallowed as a whole with a glass of water. Do not crush, chew, or break the tablets. Take the dose as prescribed by your doctor at a fixed time every day. It is recommended to take GLICLAZIDE+METFORMIN+PIOGLITAZONE with food to prevent hypoglycemia

Side Effects of Glycinorm Total 60 Tablet SR

• Hypoglycemia
• Taste change
• Nausea (feeling sick)
• Vomiting (falling sick)
• Diarrhoea
• Stomach ache
• Respiratory infection
• Weight gain
• bone fracture
• Numbness
• Vision problems

Similar Drugs

For informational purposes only. Consult a doctor before taking any medicines.

In-Depth Precautions and Warning

Drug Warnings

GLICLAZIDE+METFORMIN+PIOGLITAZONE may cause ‘lactic acidosis’ (buildup of lactic acid in the blood), characterized by abdominal pain, muscle cramps, vomiting, severe fatigue, and difficulty breathing. It is a life-threatening condition that requires immediate medical attention. Inform your doctor if you have any severe liver or kidney problems as their normal functioning is required to eliminate excess lactic acid from the body.  Do not consume excess alcohol as it increases the risk of lactic acidosis. It should be used with caution in patients with heart diseases as it increases the risk of heart failure.

Drug Interactions

Drug-Drug Interaction:

Do not take the antifungal drug (miconazole and fluconazole) or iodine contrast agents (used for X-ray or scan) while using GLICLAZIDE+METFORMIN+PIOGLITAZONE. GLICLAZIDE+METFORMIN+PIOGLITAZONE may interact with medications used to treat high blood pressure like (ritodrine, salbutamol, and bosentan), bile acid sequestrants (lower cholesterol levels), drugs used to treat skin inflammation such as corticosteroids, pain killer (phenylbutazone), a medication used to treat mental illness (chlorpromazine), a medication used to reduce urine production (desmopressin), a medication used to treat endometriosis (danazol), antidiabetics (gemfibrozil), and antibiotics (rifampicin).

Drug-Disease Interaction:

GLICLAZIDE+METFORMIN+PIOGLITAZONE should be avoided in patients with congestive heart failure (heart-related issues), type I diabetes, liver diseases, kidney diseases, hormonal problems, and infectious illnesses and oedema.

Safety Advice

ALCOHOL

Alcohol may increase the risk of side-effects and worsen the condition.

PREGNANCY

GLICLAZIDE+METFORMIN+PIOGLITAZONE is a category C drug and may cause harmful effects to the unborn baby. So, it is used only when the benefits of this medicine outweigh the risks.

BREAST FEEDING

GLICLAZIDE+METFORMIN+PIOGLITAZONE should not be used in breastfeeding mothers as it may get secreted in the breast milk and cause unwanted effects in the nursing babies.

DRIVING

GLICLAZIDE+METFORMIN+PIOGLITAZONE may cause vision problems. So, do not drive or operate heavy machinery if you have any problems with your vision while using GLICLAZIDE+METFORMIN+PIOGLITAZONE.

LIVER

GLICLAZIDE+METFORMIN+PIOGLITAZONE should be taken with caution especially if you have a history of liver diseases/conditions. The dose may have to be adjusted by your doctor.

KIDNEY

GLICLAZIDE+METFORMIN+PIOGLITAZONE should be taken with caution in patients with kidney diseases. The dose may have to be adjusted by your doctor.