PRODUCT DETAILS

About E Grain Tablet

CAFFEINE+ERGOTAMINE+PARACETAMOL+PROCHLORPERAZINE is a combination medicine indicated to treat and prevent migraine. CAFFEINE+ERGOTAMINE+PARACETAMOL+PROCHLORPERAZINE is used to relieve the symptoms at the first sign of a migraine attack and to prevent the worsening of the attack. Migraine is a neurological condition which is characterised by the intense pulsating, throbbing, pounding, debilitating headache which usually occurs on one side of the head; however, it can occur on both sides or shift.
 
CAFFEINE+ERGOTAMINE+PARACETAMOL+PROCHLORPERAZINE is a combination of four drugs, namely: Ergotamine (ergot alkaloid), caffeine (methylxanthine), prochlorperazine (anti-emetic) and paracetamol (analgesic). Ergotamine works by narrowing the blood vessels in the brain, and also affects the blood flow patterns associated with headache. Caffeine enhances the vasoconstrictive effect (narrowing of blood vessels). Prochlorperazine prevents nausea and vomiting associated with migraine by modifying the effects of neurotransmitters. Paracetamol blocks the release of prostaglandins that cause pain.

Uses of E Grain Tablet

Migraine

Medicinal Benefits of E Grain Tablet

CAFFEINE+ERGOTAMINE+PARACETAMOL+PROCHLORPERAZINE is a combination of four drugs, namely: Ergotamine, caffeine, prochlorperazine, and paracetamol. CAFFEINE+ERGOTAMINE+PARACETAMOL+PROCHLORPERAZINE is indicated to treat and prevent migraine. Ergotamine is an ergot alkaloid that works by narrowing the blood vessels in the brain, and also affects the blood flow patterns associated with headache. Caffeine is a methylxanthine that enhances the vasoconstrictive effect (narrowing of blood vessels). Prochlorperazine is an anti-emetic that prevents nausea and vomiting associated with migraine by modifying the effects of neurotransmitters. Paracetamol is an analgesic that blocks the release of prostaglandins that cause pain. CAFFEINE+ERGOTAMINE+PARACETAMOL+PROCHLORPERAZINE is used to relieve the symptoms at the first sign of a migraine attack and to prevent the worsening of the attack.

Directions for Use

Take CAFFEINE+ERGOTAMINE+PARACETAMOL+PROCHLORPERAZINE with or without food. Swallow CAFFEINE+ERGOTAMINE+PARACETAMOL+PROCHLORPERAZINE as a whole with a glass of water; do not chew, or break the tablet. Based on your medical condition, your doctor will decide how long you need to take CAFFEINE+ERGOTAMINE+PARACETAMOL+PROCHLORPERAZINE.

Side Effects of E Grain Tablet

• Stomach upset
• Dizziness
• Dry mouth
• Constipation
• Insomnia (trouble sleeping)

Similar Drugs

For informational purposes only. Consult a doctor before taking any medicines.

In-Depth Precautions and Warning

Drug Warnings

Do not take CAFFEINE+ERGOTAMINE+PARACETAMOL+PROCHLORPERAZINE if you are allergic to any of its contents; if you have/had heart problems, blood circulation problems or if you are taking antibiotics, anti-fungal, anti-HIV or other anti-migraine medicines. CAFFEINE+ERGOTAMINE+PARACETAMOL+PROCHLORPERAZINE, when taken along with antibiotics, anti-fungal, anti-HIV drugs, could lead to unpleasant side-effects such as poor blood flow to hands, feet, or brain. CAFFEINE+ERGOTAMINE+PARACETAMOL+PROCHLORPERAZINE contains paracetamol, do not take other medicines containing paracetamol along with CAFFEINE+ERGOTAMINE+PARACETAMOL+PROCHLORPERAZINE. Inform your doctor before taking CAFFEINE+ERGOTAMINE+PARACETAMOL+PROCHLORPERAZINE if you have or had high blood pressure, heart problems, high cholesterol, diabetes, asthma, liver and kidney problems. Do not take CAFFEINE+ERGOTAMINE+PARACETAMOL+PROCHLORPERAZINE if you are pregnant or breastfeeding. CAFFEINE+ERGOTAMINE+PARACETAMOL+PROCHLORPERAZINE may cause drowsiness and dizziness, so drive only if you are alert. CAFFEINE+ERGOTAMINE+PARACETAMOL+PROCHLORPERAZINE is not recommended for children as the safety and effectiveness have not been established. Avoid consuming alcohol along with CAFFEINE+ERGOTAMINE+PARACETAMOL+PROCHLORPERAZINE as it could lead to increased drowsiness. Do not take any other NSAID's for pain relief along with CAFFEINE+ERGOTAMINE+PARACETAMOL+PROCHLORPERAZINE unless prescribed. 

Drug-Drug Interaction:

CAFFEINE+ERGOTAMINE+PARACETAMOL+PROCHLORPERAZINE may have interaction with antibiotics (clarithromycin, erythromycin, troleandomycin), anti-fungal (itraconazole, ketoconazole) and anti-HIV medicines (indinavir, nelfinavir, ritonavir), a decongestant (oxymetazoline), pain killers (acetaminophen, butalbital, fentanyl), anti-depressant (fluoxetine, duloxetine), anti-anxiety (diazepam, lorazepam, alprazolam), antacid (ranitidine), antihistamine (diphenhydramine), anti-convulsant (pregabalin), anti-hypertensive (metoprolol), bronchodilators (albuterol), anti-emetic (ondansetron).