PRODUCT DETAILS

About Duloxee M Tablet

DULOXETINE+METHYLCOBALAMIN belongs to the class of medications called ‘anticonvulsants’ used to treat neuropathic pain. Neuropathic pain is a chronic (long-term) progressive nerve disease that causes nerve pain due to nerve damage or the nervous system's malfunctioning. It is mostly seen in patients who had suffered a trauma or nerve injury, diabetes, vitamin deficiencies, cancer, multiple sclerosis (disease of the brain and spinal cord), shingles (a viral infection), and HIV.

DULOXETINE+METHYLCOBALAMIN is a combination of two medicines: Duloxetine and Methylcobalamin. Duloxetine is a selective-serotonin reuptake (SSRI) inhibitor that works by increasing the levels of a chemical messenger (like serotonin and noradrenaline) in the brain required to regulate pain that travels through damaged nerves. On the other hand, Methylcobalamin is a form of vitamin B12 that helps rejuvenate and protect damaged nerve cells by producing a substance called myelin (a protective layer of nerve cells). 

DULOXETINE+METHYLCOBALAMIN is available in the form of tablets. You should take this medicine as prescribed by your doctor. DULOXETINE+METHYLCOBALAMIN may cause side effects such as drowsiness, nausea, constipation, headache, dry mouth, increased sweating, anorexia (loss of appetite), and hot sensation (burning pain). Inform your doctor if any of these side effects persist.

Do not take DULOXETINE+METHYLCOBALAMIN if you are allergic to Duloxetine, Methylcobalamin, or any contents of it. Before taking DULOXETINE+METHYLCOBALAMIN, inform your doctor if you have liver or kidney disease, seizures (fits), mania, bipolar disorder, glaucoma (an eye condition), bleeding disorders, or are at risk of hyponatremia (low sodium levels, especially in patients taking diuretics or water pills). It is not recommended for use in children and young adults as it increases the risk of suicidal tendencies. Inform your doctor if you are pregnant or breastfeeding before using DULOXETINE+METHYLCOBALAMIN. 

Uses of Duloxee M Tablet

Neuropathic pain

Medicinal Benefits of Duloxee M Tablet

DULOXETINE+METHYLCOBALAMIN is a combination of two medicines: Duloxetine and Methylcobalamin. Duloxetine is a selective-serotonin reuptake (SSRI) inhibitor that increases serotonin levels and noradrenaline in the brain required for regulating pain through the damaged nerves. Methylcobalamin is a form of vitamin B12 that helps in rejuvenating and protecting damaged nerve cells by producing a substance called myelin (the protective layer of nerve cells). Together, DULOXETINE+METHYLCOBALAMIN effectively treats neuropathic pain and improves nerve conduction for proper nerve signal functioning in the body. 

Directions for Use

DULOXETINE+METHYLCOBALAMIN is available in the form of tablets. Tablets: Swallow the DULOXETINE+METHYLCOBALAMIN tablet as a whole with a glass of water; do not chew, or break the tablet. It can be taken with or without food. Based on your medical condition, your doctor will decide the dose and how long you need to take DULOXETINE+METHYLCOBALAMIN.

Side Effects of Duloxee M Tablet

• Drowsiness
• Nausea
• Constipation
• Headache
• Dry mouth
• Increased sweating
• Anorexia (loss of appetite)
• Hot sensation (burning pain)

Similar Drugs

For informational purposes only. Consult a doctor before taking any medicines.

In-Depth Precautions and Warning

Drug Warnings

Before taking DULOXETINE+METHYLCOBALAMIN, inform your doctor if you have taken any antidepressants within the last 14 days or any medications used to treat infections. Please consult your doctor before stopping the medicine as it may cause withdrawal symptoms such as dizziness, tingling sensation, sleep disturbances, restlessness, nausea or vomiting, headache, or excessive sweating. So, do not abruptly stop taking medicine even if your symptoms improve. It may increase suicidal thoughts, so it is advised to use caution in patients with mania, bipolar disorder, or depression. Prolonged use of DULOXETINE+METHYLCOBALAMIN may decrease sodium levels, and affect blood pressure, and blood sugar levels, so regular medical check-ups are required. DULOXETINE+METHYLCOBALAMIN may increase your bleeding risk, and worsen your glaucoma condition. Hence, if you experience any eye problem or a bleeding problem, consult a doctor. 

Drug Interactions

Drug-Drug Interaction:

DULOXETINE+METHYLCOBALAMIN may interact with antidepressants (moclobemide, paroxetine, fluoxetine, venlafaxine, clomipramine, and amitriptyline), antibiotic (linezolid), opioid analgesic (tramadol), and a herbal medication used to treat skin problems (Hypericum perforatum).

Drug-Disease Interaction:

 DULOXETINE+METHYLCOBALAMIN should be used with caution in patients with liver diseases, kidney diseases, heart problems, glaucoma (increased pressure in the eye), alcoholism, drug abuse, and suicidal tendencies.

Safety Advice

ALCOHOL

Alcohol may worsen the condition by increasing the risk of side-effects

PREGNANCY

DULOXETINE+METHYLCOBALAMIN is a category C medicine, so it is not recommended for use in pregnant women.

BREAST FEEDING

DULOXETINE+METHYLCOBALAMIN should be used with caution in breastfeeding mothers.

DRIVING

DULOXETINE+METHYLCOBALAMIN may cause drowsiness. So, avoid driving or operating heavy machinery while using DULOXETINE+METHYLCOBALAMIN.

LIVER

DULOXETINE+METHYLCOBALAMIN should be used with caution in patients with liver diseases. Dose adjustments may be necessary

KIDNEY

DULOXETINE+METHYLCOBALAMIN should be used with caution in patients with kidney diseases. Dose adjustments may be necessary.