PRODUCT DETAILS

About Domgil 15 mg/20 mg Tablet

CINNARIZINE+DOMPERIDONE is a combination of anti-histamine and anti-emetic drugs, primarily used to treat Meniere's disease (inner ear disorder), which can cause vertigo (a spinning sensation or dizziness), ringing in the ears, nausea (feeling sick), vomiting, and loss of hearing. Meniere's disease occurs when the inner ear is affected and causes episodes of vertigo (spinning). It also leads to hearing problems and a ringing sound in the ear.

CINNARIZINE+DOMPERIDONE consists of two drugs: 'Cinnarizine' (anti-histamine) and 'Domperidone' (anti-emetic). Cinnarizine belongs to the class of anti-histamine drugs. It blocks the effects of histamine (a chemical substance produced in response to allergy) in the brain to reduce symptoms of travel sickness. It is also a calcium channel blocker and improves blood circulation in the inner ear, thus reducing symptoms caused by vertigo, tinnitus (ringing in the ear), and Meniere's disease. Domperidone is an anti-emetic drug (eases vomiting symptoms) and dopamine (chemical messenger) antagonist. It works by blocking the action of dopamine in the brain, which causes nausea and vomiting. It also increases the movements and contractions of stomach muscles. Domperidone is also a prokinetic agent that controls acid reflux. 

CINNARIZINE+DOMPERIDONE is available in oral tablet formulation. Your doctor will decide the dose and duration based on the severity of your disease. Common side effects of CINNARIZINE+DOMPERIDONE include drowsiness, nausea, dry mouth, indigestion, and weight gain. These side effects are not familiar to everyone and vary individually. If you notice any side effects that are not manageable, please consult your doctor.

If you use other prescription or non-prescription medicines, inform your doctor before using CINNARIZINE+DOMPERIDONE. Let your doctor know if you have any liver, kidney, or heart diseases, Parkinson's disease, blood disorders (porphyria), and allergic reactions before starting CINNARIZINE+DOMPERIDONE. CINNARIZINE+DOMPERIDONE may cause weight gain in some cases, so avoid eating junk and eat a healthy, balanced diet, including home-cooked food. Consult your doctor before taking CINNARIZINE+DOMPERIDONE if you are pregnant, planning for pregnancy, or breastfeeding. Avoid consuming alcohol along with CINNARIZINE+DOMPERIDONE as it could lead to increased drowsiness. 

Uses of Domgil 15 mg/20 mg Tablet

Meniere's disease, vertigo, tinnitus, nausea, and vomiting

Medicinal Benefits of Domgil 15 mg/20 mg Tablet

CINNARIZINE+DOMPERIDONE is used to treat inner ear disorders, vertigo, nausea, and vomiting. It consists of Cinnarizine and Domperidone. Cinnarizine is an antihistamine drug. It blocks the effects of histamine (a chemical substance produced in response to allergy) in the brain to reduce symptoms of travel sickness. It is also a calcium channel blocker and improves blood circulation in the inner ear, thus reducing symptoms caused by vertigo, tinnitus (ringing in the ear), and Meniere's disease. Domperidone is an anti-emetic drug (eases vomiting symptoms) and dopamine (chemical messenger) antagonist. It works by blocking the action of dopamine in the brain, which causes nausea and vomiting. Domperidone is also a prokinetic agent that controls acid reflux and increases stomach muscle movements and contractions.

Directions for Use

CINNARIZINE+DOMPERIDONE is available in oral tablet form. Tablet: Take CINNARIZINE+DOMPERIDONE with or without food. Swallow CINNARIZINE+DOMPERIDONE as a whole with a glass of water, do not chew, or break the tablet.

Side Effects of Domgil 15 mg/20 mg Tablet

• Drowsiness
• Nausea
• Dry mouth
• Indigestion
• Weight gain 
• Headache
• Tiredness

Similar Drugs

For informational purposes only. Consult a doctor before taking any medicines.

In-Depth Precautions and Warning

Drug Warnings

Inform your doctor if you have a history of renal failure, liver diseases, Parkinson's disease (brain disorder), blood disorders (porphyria), heart rhythm problems, and cardiac arrest before starting CINNARIZINE+DOMPERIDONE. Let your doctor know beforehand if you use any medicines treating fungal/bacterial infections and AIDS/HIV.

CINNARIZINE+DOMPERIDONE can cause weight gain, hence it is advised to maintain a well-balanced, healthy lifestyle. CINNARIZINE+DOMPERIDONE is not recommended if you are breastfeeding since it is excreted into breast milk and affects the heart of a breastfed infant. Please consult your doctor if you are pregnant and planning to conceive if the doctor advised you CINNARIZINE+DOMPERIDONE. Avoid consuming alcohol along with CINNARIZINE+DOMPERIDONE as it could lead to increased dizziness and drowsiness. CINNARIZINE+DOMPERIDONE may cause sleepiness, so drive only if you are alert. 

Drug Interactions

Drug-Drug Interaction:

CINNARIZINE+DOMPERIDONE may interact with antidepressants (citalopram, escitalopram, amitriptyline, dosulepin, imipramine), anti-fungal agents (ketoconazole, fluconazole, voriconazole), antibiotics (erythromycin, clarithromycin, telithromycin, moxifloxacin, pentamidine), heart-related drugs (amiodarone, dronedarone, quinidine, disopyramide, dofetilide, sotalol, diltiazem, verapamil), antipsychotics (haloperidol, pimozide, sertindole), stomach related drugs (cisapride, dolasetron, prucalopride), anti-allergic drugs (mequitazine, mizolastine), anti-malarial medicine (halofantrine), anti-cancer drugs (toremifene, vandetanib, vincamine), drugs treating HIV/AIDS (ritonavir), and pain killers (opioids).

Drug-Disease Interaction:

Before using CINNARIZINE+DOMPERIDONE, let your doctor know if you have any renal failure, liver diseases, Parkinson's disease (brain disorder), blood disorders (porphyria), heart rhythm problems, or cardiac arrest.

Safety Advice

ALCOHOL

You are recommended to avoid alcohol consumption while taking CINNARIZINE+DOMPERIDONE. Alcohol intake, along with CINNARIZINE+DOMPERIDONE, may cause increased dizziness and drowsiness.

PREGNANCY

It is not recommended to use CINNARIZINE+DOMPERIDONE during pregnancy. Please consult your doctor if you are pregnant or planning to conceive before using CINNARIZINE+DOMPERIDONE.

BREAST FEEDING

 

• CINNARIZINE+DOMPERIDONE is excreted into breast milk when used by a breastfeeding mother and affects the heart of a breastfed infant. It is not recommended for use during breastfeeding. Please consult your doctor before taking CINNARIZINE+DOMPERIDONE.

DRIVING

CINNARIZINE+DOMPERIDONE may make you feel drowsy. Do not drive or operate machinery if you experience drowsiness.

LIVER

CINNARIZINE+DOMPERIDONE should be cautiously administered in patients with liver diseases. Please consult your doctor if you have a history of liver impairment before starting CINNARIZINE+DOMPERIDONE.

KIDNEY

CINNARIZINE+DOMPERIDONE should be cautiously administered in patients with kidney problems. Please consult your doctor if you have a history of kidney impairment/kidney disease.