PRODUCT DETAILS

About Dolitol 75 SR Tablet

INDOMETHACIN belongs to the group of pain killers known as NSAID's (Non-Steroidal Anti-Inflammatory Drugs) used to relieve symptoms caused by osteoarthritis, ankylosing spondylitis, and rheumatoid arthritis such as stiffness, swelling and joint pain. INDOMETHACIN is also used to treat acute gouty arthritis, musculoskeletal pain, lower back pain, period pain, pain following joint and bone surgery.

Uses of Dolitol 75 SR Tablet

Osteoarthritis, Ankylosing spondylitis, Rheumatoid arthritis

Medicinal Benefits of Dolitol 75 SR Tablet

INDOMETHACIN belongs to the group of pain killers known as NSAID's (Non-Steroidal Anti-Inflammatory Drugs). INDOMETHACIN is used to relieve symptoms caused by osteoarthritis, ankylosing spondylitis, and rheumatoid arthritis such as stiffness, swelling and joint pain. INDOMETHACIN is also used to treat acute gouty arthritis, musculoskeletal pain, lower back pain, period pain, pain following joint and bone surgery. INDOMETHACIN works by blocking the effect of a chemical messenger in your body, known as cyclo-oxygenase (COX) enzymes that make another chemical 'prostaglandins' (PG). These prostaglandins are produced at injury sites and cause pain and swelling. By blocking the effect of COX enzymes, lesser PGs are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site

Directions for Use

Take INDOMETHACIN with or immediately after food or with milk or antacids. Take INDOMETHACIN at the same time every day for best results. The tablet form of INDOMETHACIN should be swallowed as a whole with a glass of water or milk; do not chew, break, or crush the tablet. The liquid form of INDOMETHACIN should be taken by mouth using the measuring cup provided by the pack; shake the pack well before each use. The suppository form of INDOMETHACIN should be inserted into the rectum. Do not swallow the suppository.

Side Effects of Dolitol 75 SR Tablet

Like all medicines, INDOMETHACIN can also cause side-effects, although not everybody experiences them. Headache, dizziness, diarrhoea, vomiting, and constipation are the common side-effects of INDOMETHACIN. Please consult your doctor if you experience any of these side-effects persistently.

Similar Drugs

For informational purposes only. Consult a doctor before taking any medicines.

In-Depth Precautions and Warning

Drug Warnings

INDOMETHACIN can increase your risk of having a fatal heart attack, chest pain (angina) or stroke. So, tell your doctor that you are using INDOMETHACIN before undergoing heart bypass surgery (CABG) or graft surgery. Do not take INDOMETHACIN if you are allergic to INDOMETHACIN, have severe heart failure, have suffered bleeding problems such as bleeding from stomach or bowels while taking any pain killers or you have liver or kidney problems. Do not take INDOMETHACIN if you are pregnant or breastfeeding unless prescribed. INDOMETHACIN causes drowsiness and dizziness, so drive only if you are alert. INDOMETHACIN should not be given to children as the safety have not been established. Avoid consuming alcohol along with INDOMETHACIN as it could lead to increased drowsiness and can increase the risk of stomach bleeding. Stop taking INDOMETHACIN and consult your doctor immediately if you have stomach pain or any signs of bleeding in intestine or stomach like blood in stools.

Drug Interactions

Drug-Drug Interaction:

INDOMETHACIN may have interaction with ibuprofen, naproxen, and aspirin (used to relieve pain), duloxetine (used to treat depression), metoprolol (used to treat high blood pressure), celecoxib, and prednisone (used to treat arthritis).

Drug-Disease Interaction:

 INDOMETHACIN should not be given in patients with heart failure, fluid retention (oedema), asthma, gastrointestinal toxicity, high blood pressure, hyperkalemia (high levels of potassium), thrombosis (formation of clots), anaemia (low red blood cells), rash, platelet aggregation inhibition, CNS problems, kidney and liver toxicity.

Safety Advice

ALCOHOL

You are recommended to avoid alcohol consumption while taking INDOMETHACIN. Alcohol intake, along with INDOMETHACIN, may cause increased dizziness and drowsiness. It may also elevate the risk of stomach bleeding.

PREGNANCY

It is not recommended to take INDOMETHACIN while you are pregnant. Please consult your doctor if you are pregnant or if you are having any concerns regarding this.

BREAST FEEDING

It is not recommended to take INDOMETHACIN while you are breastfeeding. Please consult your doctor if you are breastfeeding or if you are having any concerns regarding this.

DRIVING

INDOMETHACIN may cause drowsiness, dizziness, tiredness and vision disturbances, do not drive or operate heavy machinery if you feel dizzy.

LIVER

Dose adjustment may be needed. INDOMETHACIN should be taken with caution in patients with liver impairment/liver disease. Please consult your doctor if you have liver problems with symptoms of yellowing of skin/eyes, difficulty in peeing or feeling exhausted all the time.

KIDNEY

Dose adjustment may be needed. INDOMETHACIN should be taken with caution in patients with kidney impairment/kidney disease. Please consult your doctor if you have kidney impairment or any concerns regarding this.