PRODUCT DETAILS

About Crevast-F 5 Tablet

FENOFIBRATE+ROSUVASTATIN belongs to the class of lipid-lowering agents used to lower an increased level of total cholesterol (TC) and triglyceride (TG) level. This prevents the risk of having any cardiovascular events like heart attack, stroke, and heart-related chest pain (angina) in the future. The blockage of the heart occurs due to the increased level of bad cholesterol (low-density lipoprotein -LDL and triglycerides - TG) which build-up of fat, cholesterol, and other waxy substances layers forming a plaque in the lining of the arteries wall (coronary arteries). This increases the chance of having a blood clot and heart attack on an individual.

FENOFIBRATE+ROSUVASTATIN contains Rosuvastatin (statin) and Fenofibrate (fibric acid derivative). Rosuvastatin lowers the levels of raised lipids known as cholesterol and triglycerides in the blood and increases the ‘good’ cholesterol (HDL) by blocking our body’s production of ‘bad’ cholesterol. It also improves your body’s ability to remove it from your blood. On the other hand, Fenofibrate works by lowering the level of triglyceride in the blood. 

You can take FENOFIBRATE+ROSUVASTATIN with food or without food. It should be swallowed whole with a glass of water. Do not chew, bite, or break it. Your doctor will advise you on how often you take your tablets based on your medical condition. In some cases, you may experience nausea, headache, abdominal pain, muscle pain, weakness, and daytime drowsiness. Most of these side effects of FENOFIBRATE+ROSUVASTATIN do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.    

It is important to have your cholesterol and triglyceride levels (lipid profile) checked regularly. This medicine is only one part of a treatment program which should also include a healthy low-fat diet, regular exercise, smoking cessation, moderation of alcohol intake, and weight reduction. You can eat normally while taking this medicine, but try to avoid foods that are high in fat. And also, please inform your doctor before starting FENOFIBRATE+ROSUVASTATIN if you have kidney problems, are pregnant or breastfeeding, or are diabetic (as you need to monitor your sugar level regularly).

Uses of Crevast-F 5 Tablet

Hypertriglyceridemia, Hypercholesterolemia, and Mixed dyslipidemia.

Medicinal Benefits of Crevast-F 5 Tablet

FENOFIBRATE+ROSUVASTATIN is beneficial for patients with Hypertriglyceridemia (high level of triglycerides), Hypercholesterolemia (high level of cholesterol), and Mixed Dyslipidaemia (elevated level of triglycerides – TG, low-density lipoprotein – LDL, and low level of high-density lipoprotein – HDL). Rosuvastatin first increases the LDL (bad cholesterol) on the liver cells for uptake and breakdown. Then, it stops the synthesis of very-low-density lipoprotein (VLDL) made by the liver to reduce the total number of bad cholesterols (LDL and VLDL). Fenofibrate works by increasing the enzyme (a natural substance) that breaks down fats or lipids present in the blood. Besides this, Fenofibrate also reduces the raised uric acid levels by increasing the excretion of uric acid through urination. It is also prescribed to diabetes patients with an increased level of lipid and cholesterol to minimize cardiovascular risks like heart attack, stroke, and heart-related chest pain (angina).

Directions for Use

Swallow FENOFIBRATE+ROSUVASTATIN as a whole with water; do not crush, break or chew it. It is better to take it at a fixed time.

Side Effects of Crevast-F 5 Tablet

• Nausea
• Headache
• Abdominal pain
• Muscle pain (myalgia)
• General weakness
• Daytime drowsiness

Similar Drugs

For informational purposes only. Consult a doctor before taking any medicines.

In-Depth Precautions and Warning

Drug Warnings

Prolonged intake of statins is reported to cause severe musculoskeletal problems like myopathy and rhabdomyolysis. The most common adverse reactions associated with the use of FENOFIBRATE+ROSUVASTATIN are muscle pain, muscle weakness, stomach upset, nausea, headache, and asthenia (general unexplained weakness). Elderly patients are at greater risk of having muscle problems so it should be given with caution and only after consulting the doctor. Rosuvastatin present in FENOFIBRATE+ROSUVASTATIN is a pregnancy category X medicine (high risk to both pregnant mother and fetus). Hence, it should not be used by pregnant or lactating mothers. FENOFIBRATE+ROSUVASTATIN also passes into the breast milk but its safety and efficiency are unclear, so its intake should be avoided by the nursing mother. The use of a FENOFIBRATE+ROSUVASTATIN should be avoided in all kidney patients and to be taken with caution in all liver disease patients. The use of alcohol with FENOFIBRATE+ROSUVASTATIN increases liver damage, so its use should be avoided. FENOFIBRATE+ROSUVASTATIN contains fenofibrate which is contraindicated in gallstone patients, as there is an increased level of cholesterol in the bile leading to cholelithiasis.

Drug Interactions

Drug-Drug Interaction:

FENOFIBRATE+ROSUVASTATIN has shown interactions with the immune system affecting medicine (cyclosporine), bile affecting pills (niacin, gemfibrozil, bile acid resin), anti-HIV drugs (lopinavir, ritonavir, atazanavir, ritonavir, tipranavir/ritonavir, fosamprenavir/ritonavir), anti-coagulant or blood thinners (coumadin, warfarin), and anti-arthritis pills (colchicine). So if you are taking these drugs tell your doctor before taking FENOFIBRATE+ROSUVASTATIN.

Drug-Disease Interaction:

FENOFIBRATE+ROSUVASTATIN should not be given in the condition of liver diseases like biliary cirrhosis (fatty liver disease), gall stones (cholelithiasis), kidney disease, muscle disease like myopathy, and rhabdomyolysis.

Safety Advice

ALCOHOL

You are recommended not to consume alcohol along with FENOFIBRATE+ROSUVASTATIN to avoid unpleasant side effects like drowsiness, dizziness, or sleepiness. It may also lead to a life-threatening condition like coma if taken with excessive alcohol.

PREGNANCY

Rosuvastatin present in FENOFIBRATE+ROSUVASTATIN is a pregnancy category X medicine that can harm both the pregnant mother and the unborn baby (fetus). So, it is better to avoid its intake and consult the doctor before taking FENOFIBRATE+ROSUVASTATIN. Your doctor will weigh the benefits and any potential risks before prescribing them to you.

BREAST FEEDING

FENOFIBRATE+ROSUVASTATIN is known to pass into breast milk and can affect the baby's health. But, whether it will harm or not is still unclear. So, it should be taken only in extreme conditions the doctor has prescribed you.

DRIVING

FENOFIBRATE+ROSUVASTATIN does not usually affect your ability to drive.

LIVER

FENOFIBRATE+ROSUVASTATIN is to be taken with caution, especially if you have a history of liver disease. The dose may have to be adjusted by your doctor.

KIDNEY

FENOFIBRATE+ROSUVASTATIN is to be taken with caution, especially if you have a history of kidney disease or are currently in the dialysis stage. The dose may have to be adjusted by your doctor. A prolonged intake of FENOFIBRATE+ROSUVASTATIN can lead to liver enzyme abnormalities.