PRODUCT DETAILS

About Zerodol-PG 200/75 Tablet SR

ACECLOFENAC+PREGABALIN is a combination medicine used for the management of neuropathic pain. Neuropathic pain is a chronic progressive nerve disease that causes nerve pain due to nerve damage or a malfunctioning nervous system. The pain could be intermittent or continuous, which is felt as a prickling, stabbing, tingling, or burning sensation.

ACECLOFENAC+PREGABALIN is a combination of two drugs: Pregabalin (anti-convulsant), and Aceclofenac (NSAID). Pregabalin works by changing how nerves send messages to your brain. Aceclofenac works by blocking the effect of a chemical messenger known as cyclo-oxygenase (COX) enzyme that makes another chemical 'prostaglandins' (PG). Prostaglandins play an important role in controlling pain and inflammation. By blocking the effect of COX enzymes, lesser PGs are produced. This reduces mild to moderate pain and inflammation at the injured or damaged site decreasing stiffness in joints. Together, ACECLOFENAC+PREGABALIN helps to treat neuropathic pain (pain due to nerve damage).

Take ACECLOFENAC+PREGABALIN with or without food. Swallow ACECLOFENAC+PREGABALIN as a whole with a glass of water; do not chew, or break the tablet. You are advised to take ACECLOFENAC+PREGABALIN for as long as your doctor has prescribed it for you depending on your medical condition. In some cases, you may experience certain common side effects such as nausea, vomiting, stomach pain, diarrhea, loss of appetite, heartburn, dryness in the mouth, dizziness, sleepiness, and uncoordinated body movements. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Please do not stop taking ACECLOFENAC+PREGABALIN without consulting your doctor as it could cause withdrawal symptoms. Do not take ACECLOFENAC+PREGABALIN if you are pregnant or breastfeeding unless prescribed by the doctor. Women of child-bearing potential should use effective contraception. ACECLOFENAC+PREGABALIN causes drowsiness and dizziness, so drive only if you are alert. ACECLOFENAC+PREGABALIN should not be given to children as safety and effectiveness have not been established. Avoid consuming alcohol along with ACECLOFENAC+PREGABALIN as it could lead to increased dizziness and sleepiness. Keep your doctor informed about your health condition and medicines to rule out any side effects. Before taking this medicine inform your doctor have a history of heart disease, severe kidney disease, disorders of the stomach or gut/bowel, or diabetes.

Uses of Zerodol-PG 200/75 Tablet SR

Neuropathic pain

Medicinal Benefits of Zerodol-PG 200/75 Tablet SR

ACECLOFENAC+PREGABALIN is a combination of two drugs: Pregabalin (anti-convulsant), and Aceclofenac (NSAID's). Pregabalin belongs to a group of medications called 'anticonvulsants' used to prevent neuropathic pain (pain due to damaged nerves), fibromyalgia (musculoskeletal pain), and epilepsy (fits). It works by calming the damaged or overactive nerves in your body that may cause pain or seizures, thereby decreasing the number of pain signals sent out by damaged nerves in the body. Overall it reduces the pain which has been damaged or irritated due to conditions like chronic conditions, diabetes, trauma, or epilepsy. Aceclofenac belongs to a group of medicines called Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) used to reduce and relieve pain, redness, and inflammation (swelling) in patients suffering from osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis. ACECLOFENAC+PREGABALIN works by blocking the effect of a chemical messenger known as cyclo-oxygenase (COX) enzyme that makes another chemical 'prostaglandins' (PG). These prostaglandins are produced at injury sites and cause pain and swelling. By blocking the effect of COX enzymes, lesser PGs are produced. This helps in reducing mild to moderate pain and inflammation at the injured or damaged site. Together, ACECLOFENAC+PREGABALIN helps to treat neuropathic pain (pain due to nerve damage).

Directions for Use

Take ACECLOFENAC+PREGABALIN with or without food. Swallow ACECLOFENAC+PREGABALIN as a whole with a glass of water; do not chew, or break the tablet. Based on your medical condition, your doctor will decide how long you need to take ACECLOFENAC+PREGABALIN.

Side Effects of Zerodol-PG 200/75 Tablet SR

• Nausea
• Vomiting
• Stomach pain
• Diarrhea
• Heartburn
• Dryness in mouth
• Dizziness
• Blurred vision
• Weight gain
• Sleepiness
• Tiredness
• Uncoordinated body movements

Similar Drugs

For informational purposes only. Consult a doctor before taking any medicines.

In-Depth Precautions and Warning

Drug Warnings

Inform your doctor before taking ACECLOFENAC+PREGABALIN if you have heart problems, bipolar syndrome, severe liver disease or porphyria, diabetes, and asthma. Please do not stop taking ACECLOFENAC+PREGABALIN without consulting your doctor as it could cause withdrawal symptoms. Do not take ACECLOFENAC+PREGABALIN if you are pregnant or breastfeeding unless prescribed by the doctor. ACECLOFENAC+PREGABALIN causes drowsiness and dizziness, so drive only if you are alert. ACECLOFENAC+PREGABALIN should not be given to children as safety and effectiveness have not been established. Avoid consuming alcohol along with ACECLOFENAC+PREGABALIN as it could lead to increased drowsiness and sleepiness. Consult your doctor immediately if you experience suicidal tendencies such as killing or harming yourself. ACECLOFENAC+PREGABALIN contains Pregabalin, which can decrease sperm count and may affect fertility in men. Do not exceed the prescribed dose or duration of treatment.

Drug Interactions

Drug-Drug Interaction:

ACECLOFENAC+PREGABALIN may have interaction with oral diabetes medicine (pioglitazone, rosiglitazone) and medication used primarily to treat high blood pressure and heart failure (benazepril, captopril, enalapril, fosinopril, lisinopril, moexipril, perindopril, quinapril, ramipril).

Drug-Disease Interaction:

 ACECLOFENAC+PREGABALIN may have interactions with disease conditions such as severe kidney disease, diabetes, drug or alcohol addiction, heart problems, a mood disorder, depression, or suicidal thoughts.

Safety Advice

ALCOHOL

Avoid consumption of alcohol while taking ACECLOFENAC+PREGABALIN as it may increase drowsiness and sleepiness.

PREGNANCY

Please consult your doctor if you have any concerns regarding this, your doctor will prescribe only if the benefits outweigh the risks.

BREAST FEEDING

Consult your doctor before taking ACECLOFENAC+PREGABALIN; your doctor will decide whether ACECLOFENAC+PREGABALIN can be taken by breastfeeding mothers or not.

DRIVING

ACECLOFENAC+PREGABALIN causes drowsiness, sleepiness, and blurred vision. Do not drive or operate machinery unless you are alert.

LIVER

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

KIDNEY

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.