PRODUCT DETAILS

About Unotrip 15mg Tablet

NORTRIPTYLINE belongs to a group of medicines called 'tricyclic antidepressants' primarily used to treat depression. Additionally, it is also used to treat neuropathic pain and bedwetting at night. Depression is a mental illness or disorder characterized by persistently depressed mood or loss of interest in activities, causing significant impairment in daily life.

NORTRIPTYLINE contains Nortriptyline that works by affecting certain chemical messengers (serotonin, norepinephrine) in the brain which communicate between brain cells, thereby regulating mood and preventing depression. Besides this, NORTRIPTYLINE also the transmission of pain signals, thereby provides relief from neuropathic pain.

Uses of Unotrip 15mg Tablet

Depression

Medicinal Benefits of Unotrip 15mg Tablet

NORTRIPTYLINE belongs to a group of medicines called tricyclic antidepressants used to prevent depression. It works by affecting certain chemical messengers (serotonin and/or norepinephrine) in the brain which communicate between brain cells, thereby helps in regulating mood and treats depression. NORTRIPTYLINE prevents the transmission of pain signals, thereby provides relief from neuropathic pain.

Directions for Use

Oral tablet/capsule: Take NORTRIPTYLINE with or without food as advised by your doctor and swallow whole with a glass of water. Do not crush, chew or break it. Liquid oral syrup: Shake the bottle before use. Check the label for directions and take NORTRIPTYLINE with or without food in dose as prescribed by your doctor with the help of a measuring cup.

Side Effects of Unotrip 15mg Tablet

• Increased heart rate
• Flushing
• Drowsiness
• Weight gain
• Difficulty in urination
• Constipation
• Orthostatic hypotension (sudden lowering of blood pressure on standing)
• Dryness in the mouth
• Tingling in the arms or legs
• Blurred vision

Similar Drugs

For informational purposes only. Consult a doctor before taking any medicines.

In-Depth Precautions and Warning

Drug Warnings

Do not take NORTRIPTYLINE if you are known to be allergic to NORTRIPTYLINE. Inform your doctor if you have suicidal ideation or behaviour symptoms, have heart rhythm problems or hypotension, heart disease, seizure disorders, bone marrow suppression, diabetes, schizophrenia, bipolar disorder, acute alcohol intoxication, glaucoma, thyroid problems, kidney and liver problems. Do not take NORTRIPTYLINE if you are pregnant or breastfeeding unless prescribed by the doctor. NORTRIPTYLINE should not be given to the children less than 18 years of age, as its safety and efficacy have not been established. Avoid consuming alcohol along with NORTRIPTYLINE as it could lead to increased drowsiness and dizziness. Rise slowly from sitting or lying position as NORTRIPTYLINE causes orthostatic hypotension (sudden lowering in blood pressure leading to dizziness on standing).

Drug Interactions

Drug-Drug Interaction:

NORTRIPTYLINE may have interaction with monoamine oxidase inhibitors (medicines used to treat depression) (moclobemide, phenelzine, iproniazid, isocarboxazid, nialamide, tranylcypromine, selegiline)  medicine to treat high blood pressure (diltiazem, verapamil, guanethidine, debrisoquine, bethanidine, clonidine, reserpine, methyldopa ) pain killers (tramadol, trazodone, hydrocodone, oxycodone, acetaminophen), antidepressant (bupropion, duloxetine, fluoxetine, sertraline), antihistamine (diphenhydramine, cetirizine), sedatives (zolpidem), muscle relaxant (cyclobenzaprine), medicines to treat fungal infections (fluconazole, terbinafine, ketoconazole, and itraconazole), anti-thyroid (levothyroxine).

Drug-Disease Interaction:

 If you have suicidal ideation or behavior, have disease conditions such as heart disease, seizure disorders, bone marrow suppression, diabetes, schizophrenia, bipolar disorder, acute alcohol intoxication, glaucoma, thyroid problems, kidney and liver problems.  

Safety Advice

ALCOHOL

Avoid consumption of alcohol while taking NORTRIPTYLINE as it may cause an increased sedative effect. Please consult a doctor before consuming alcohol with NORTRIPTYLINE.

PREGNANCY

Avoid taking NORTRIPTYLINE if you are pregnant unless prescribed by a doctor. Please consult your doctor if you have any concerns regarding this, your doctor will prescribe only if the benefits outweigh the risks.

BREAST FEEDING

Consult your doctor before taking NORTRIPTYLINE; your doctor will decide whether NORTRIPTYLINE can be taken by breastfeeding mothers or not.

DRIVING

NORTRIPTYLINE may affect your ability to drive or operate machinery safely. Therefore, drive only if you are alert after taking NORTRIPTYLINE.

LIVER

Take NORTRIPTYLINE with caution, especially if you have a history of liver disease/conditions. The dose may be adjusted by your doctor as required.

KIDNEY

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.