PRODUCT DETAILS

About Topnid 500mg Injection

PROGESTERONE belongs to the class of drugs called female hormones primarily used in combination with oestrogen for hormone replacement therapy. Besides this, PROGESTERONE also treats amenorrhoea (absence of menstrual periods) and prevents endometrial hyperplasia (thickened uterus lining). Hormone replacement therapy is a treatment to relieve menopause symptoms. It replaces hormones that are at a lower level as you approach menopause.

The PROGESTERONE contains a sustained-release (SR) form of progesterone that prolongs drug release for a longer duration. PROGESTERONE contains Progesterone that works by replacing oestrogen and progesterone hormone levels in the body and providing relief from menopause symptoms.

You are advised to take PROGESTERONE for as long as your doctor has prescribed it for you based on your medical condition. In some cases, you may experience dizziness, drowsiness, headache, mood changes, diarrhoea, vaginal discharge, joint pain, hot flashes (sudden feeling of warmth) or constipation. Most of these side effects of PROGESTERONE do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to soya, PROGESTERONE or any other medicines, please tell your doctor. Avoid taking PROGESTERONE if you have breast cancer, unexplained vaginal bleeding, blood clots or blood clotting disorder, liver disease, porphyria (a disorder in the formation of red blood pigment) or cerebral haemorrhage (bleeding in the brain). Avoid taking PROGESTERONE if you are pregnant as it may harm the unborn baby. You are advised to use effective birth control methods while taking PROGESTERONE to prevent pregnancy. However, if you are pregnant, planning for pregnancy or breastfeeding, please consult a doctor before taking PROGESTERONE. Drive only if you are alert as PROGESTERONE may cause drowsiness or dizziness.

Uses of Topnid 500mg Injection

Female infertility, Female hormonal imbalance 

Medicinal Benefits of Topnid 500mg Injection

PROGESTERONE contains Progesterone that is used in combination with estrogen for hormone replacement therapy. Also, PROGESTERONE is used to treat amenorrhoea (absence of menstrual periods due to lack of progesterone) and prevent endometrial hyperplasia (unusually thick lining of the uterus). PROGESTERONE is a sustained release formulation that prolongs drug release for a longer duration of time. PROGESTERONE replaces estrogen and progesterone hormone levels in the body and helps in providing relief from menopause symptoms.

Directions for Use

Take PROGESTERONE as prescribed by your doctor. Swallow it with a glass of water. Do not break, crush or chew it. It is best to take PROGESTERONE at bedtime as it may cause dizziness or drowsiness.

Side Effects of Topnid 500mg Injection

• Dizziness
• Drowsiness
• Headache
• Mood changes
• Diarrhea
• Vaginal discharge
• Joint pain
• Hot flashes (sudden feeling of warmth) 
• Constipation

Similar Drugs

For informational purposes only. Consult a doctor before taking any medicines.

In-Depth Precautions and Warning

Drug Warnings

If you are allergic to soya, PROGESTERONE, or any other medicines, please tell your doctor. Avoid taking PROGESTERONE if you have breast cancer, unexplained vaginal bleeding, blood clots or blood clotting disorder, liver disease, porphyria (a disorder in the formation of red blood pigment), or cerebral hemorrhage (bleeding in the brain). Avoid taking PROGESTERONE if you are pregnant as it may harm the unborn baby. You are advised to use effective birth control methods while taking PROGESTERONE to prevent pregnancy. However, if you are pregnant, planning for pregnancy, or breastfeeding, please consult a doctor before taking PROGESTERONE. Drive only if you are alert as PROGESTERONE may cause drowsiness or dizziness. If you have diabetes, high blood pressure, migraine or severe headaches, gallstones, asthma, fits, systemic lupus erythematosus (an autoimmune disease), or if you ever had depression, inform your doctor before taking PROGESTERONE. If you are about to undergo any surgery, please inform your doctor that you are taking PROGESTERONE.

Drug Interactions

Drug-Drug Interaction:

 PROGESTERONE may interact with anticonvulsants (carbamazepine, phenytoin, phenobarbital), anti-tuberculosis drugs (rifabutin, rifampicin), anti-HIV drugs (ritonavir, nevirapine, nelfinavir, efavirenz), benzodiazepine (diazepam), water tablet (spironolactone), immunosuppressant (ciclosporin), blood thinners (phenindione), skeletal muscle relaxants (tizanidine), antifungals (terbinafine, ketoconazole, griseofulvin).

Drug-Disease Interaction:

Avoid taking PROGESTERONE if you have breast cancer, unexplained vaginal bleeding, blood clots or blood clotting disorder, liver disease, porphyria (a disorder in the formation of red blood pigment), or cerebral hemorrhage  (bleeding in the brain). If you have diabetes, high blood pressure, migraine or severe headaches, gallstones, asthma, fits, systemic lupus erythematosus (an autoimmune disease), or if you ever had depression, inform your doctor before taking PROGESTERONE.

Safety Advice

ALCOHOL

Interaction of PROGESTERONE with alcohol is unknown. Please consult a doctor before consuming alcohol while using PROGESTERONE.

PREGNANCY

PROGESTERONE is a category B pregnancy drug and is not recommended for use during pregnancy as it may cause harm to the unborn baby. However, please consult a doctor if you are pregnant.

BREAST FEEDING

PROGESTERONE may be excreted in human milk. Therefore, please consult a doctor if you are breastfeeding.

DRIVING

PROGESTERONE may cause dizziness or drowsiness. Therefore, avoid driving if you feel dizzy or drowsy after taking PROGESTERONE.

LIVER

Please consult a doctor if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

KIDNEY

PROGESTERONE should be given with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.