PRODUCT DETAILS

About Redufen 100mg Tablet

KETOPROFEN belongs to a class of pain killers known as non-steroidal anti-inflammatory drugs (NSAIDs). KETOPROFEN is primarily used to reduce pain and swelling in muscles and joints in conditions such as osteoarthritis, rheumatoid arthritis, ankylosing spondylitis (pain and stiffness in the backbone), cervical spondylitis (wear and tear of spinal discs in neck), and acute gout (severe pain due to excess of uric acid). It is also used as a short-term treatment for muscle and back pain, tooth pain, and menstrual pain. Arthritis is a condition that causes swelling of one or more joints resulting in pain and stiffness of joints that worsen over time.

Uses of Redufen 100mg Tablet

Osteoarthritis, Rheumatoid arthritis, Ankylosing spondylitis, Tendinitis (tendon inflammation), Bursitis (inflammation of fluid-filled pads – bursae at the joints), Acute gout (joint pain due to excess uric acid), Dysmenorrhea (menstrual cramps)

Medicinal Benefits of Redufen 100mg Tablet

KETOPROFEN belongs to the group of NSAIDs (Non-Steroidal Anti-Inflammatory Drugs) used to relieve pain and inflammation. It is helpful in the conditions of rheumatoid arthritis (inflammation of your joints), ankylosing spondylitis (pain due to problems with your spine), osteoarthritis (where the cushioning (cartilage) between your bone joints is damaged). In addition to this, it is also used as a short-term treatment for muscle and back pain, tooth pain, gout, and menstrual pain. KETOPROFEN works by blocking the effect of a chemical messenger in your body, known as cyclo-oxygenase (COX) enzymes that make another chemical 'prostaglandins' (PG). These prostaglandins are produced at injury sites and cause pain and swelling. By blocking the COX enzyme's effect, lesser PGs are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site. In addition, KETOPROFEN also inhibits the lipoxygenase (LOX) enzyme pathway that makes other chemical noncyclized monohydroxy acids (HETE) and leukotrienes. By blocking the lipoxygenase enzyme, it may attenuate cell-mediated inflammation and thus retard the progression of tissue destruction in inflamed joints. Additionally, KETOPROFEN is a powerful inhibitor of bradykinin, an important chemical mediator of pain and inflammation. Also, it stabilizes lysosomal membranes against osmotic damage and prevents the release of lysosomal enzymes that mediate tissue destruction in inflammatory reaction. KETOPROFEN is more effective in relieving moderate to severe pain and improving the overall condition of the patient than other NSAIDs.

Directions for Use

Tablet/capsule form: It should be taken with a meal or just after a meal with plenty of water to avoid upset stomach in dose and duration prescribed by a doctor. Injection form: Injection should only be put at the hospital by an expert. Topical gel: Take a pea-sized amount onto your finger and apply it directly onto the affected area and gently massage it in. If KETOPROFEN comes in contact with eyes, nose, or mouth, rinse with water immediately.

Side Effects of Redufen 100mg Tablet

• Nausea
• Vomiting
• Indigestion
• Heartburn
• Dizziness
• Drowsiness
• Bruising
• Itching
• Abdominal pain
• Constipation
• Retention of fluid
• Shortness of breath

Similar Drugs

For informational purposes only. Consult a doctor before taking any medicines.

In-Depth Precautions and Warning

Drug Warnings

KETOPROFEN may cause an increased risk of severe heart problems like myocardial infarction and stroke, which can be fatal. The risk may increase for prolong use of KETOPROFEN. It should not be used by the patient who has had undergone recent heart bypass surgery or going to have it. KETOPROFEN increases the risk of severe gastrointestinal conditions like bleeding, ulceration, and perforation of the stomach or intestines, which can be fatal. Elderly patients are at greater risk for gastrointestinal bleeding problems, so the doctor can limit their dose. KETOPROFEN is not recommended for pregnant women, especially in the third trimester, as it may cause harm to the baby. Therefore, pregnant or breastfeeding women are advised to consult a doctor before taking KETOPROFEN. KETOPROFEN is contraindicated in children below 18 years of age. Do not consume alcohol with KETOPROFEN as it may increase the risk of stomach bleeding or ulcer. Stop taking KETOPROFEN and consult your doctor immediately if you have stomach pain or any signs of bleeding in the intestine or stomach, such as blood in stools. Do not take aspirin or any other NSAIDs for pain relief along with KETOPROFEN. KETOPROFEN may hide signs of infections such as fever and pain. It may delay appropriate treatment of infections like pneumonia and bacterial skin infections related to chickenpox, which may lead to an increased risk of complications.

Drug Interactions

Drug-Drug Interaction:

KETOPROFEN is shown to interact with pain killers (naproxen, aspirin, ibuprofen, tramadol, hydrocodone, oxycodone), a medicine used to treat bipolar disorder (lithium), anticancer/antimetabolites (methotrexate), blood pressure, or heart medicine (digoxin), nausea medicine (metoclopramide, domperidone),  medicines to stop blood clotting (heparin, warfarin, clopidogrel, ticlopidine, dabigatran, apixaban, rivaroxaban, edoxaban), medicines used to dissolve blood clots (streptokinase, alteplase, reteplase), antibiotics (ciprofloxacin, levofloxacin, ofloxacin), an antidepressant (fluoxetine, sertraline, citalopram, paroxetine), corticosteroids (hydrocortisone, betamethasone, prednisolone), a medicine used to terminate a pregnancy (mifepristone), used after an organ transplant (tacrolimus), diuretic/water pills (thiazides, furosemide).

Drug-Disease Interaction:

KETOPROFEN should not be given in patients with stomach/intestine ulcer or bleeding, heart failure, fluid retention (edema), asthma, high blood pressure, hyperkalemia (high levels of potassium), thrombosis (formation of clots), anemia (low red blood cells), rash, platelet aggregation inhibition, kidney and liver problems.

Safety Advice

ALCOHOL

You are recommended to avoid alcohol consumption while taking KETOPROFEN. Alcohol intake, along with KETOPROFEN, may cause increased drowsiness and drowsiness and may increase gastrointestinal ulcer risk and bleeding like other pain killers.

PREGNANCY

It is not recommended to take KETOPROFEN while you are pregnant, especially in the last trimester. Please consult an Obstetrician/Gynaecologist if you have any concerns regarding this, your doctor will prescribe you KETOPROFEN only if the benefits outweigh the risks.

BREAST FEEDING

KETOPROFEN may pass into breast milk. Please consult your doctor if you have any concerns regarding this, your doctor will decide whether breastfeeding mothers can take KETOPROFEN or not.

DRIVING

KETOPROFEN may cause drowsiness, dizziness, tiredness, and vision disturbances in some cases. So it is better not to drive a motor vehicle or operate heavy machinery if you feel dizzy.

LIVER

Take KETOPROFEN with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required

KIDNEY

Dose adjustment may be needed and should be used with caution in patients with kidney impairment/kidney disease. Please consult your doctor if you have kidney impairment or any concerns regarding this