PRODUCT DETAILS

About Oxirab O 4mg/20mg Tablet

ONDANSETRON+RABEPRAZOLE is a gastrointestinal medication, primarily used to treat nausea, vomiting, stomach ulcers, gastro-oesophageal reflux disease (GERD), heartburn, and erosive oesophagitis (acid-related damage to the lining of the oesophagus). ONDANSETRON+RABEPRAZOLE is also used to treat infections caused by Helicobacter pylori and Zollinger-Ellison syndrome. GERD is a condition that occurs when stomach acid frequently flows back into the food pipe (oesophagus). Zollinger Ellison syndrome is a rare condition in which a gastrin-secreting tumour of the pancreas causes excessive acid production leading to peptic ulcers.

ONDANSETRON+RABEPRAZOLE contains two medicines: Rabeprazole and Ondansetron. Rabeprazole belongs to the group of drugs called ‘proton pump inhibitors.’ It blocks the action of the gastric proton pump that is responsible for the production of acid in the stomach. This reduces the amount of acid produced, heals the ulcers, and prevents the formation of new ulcers. Ondansetron belongs to the class of anti-emetics (prevents vomiting). It works by blocking the action of serotonin (chemical messenger) that triggers nausea and vomiting.

Uses of Oxirab O 4mg/20mg Tablet

Nausea, vomiting, stomach ulcers, gastro-oesophageal reflux disease (GERD), heartburn, erosive oesophagitis and Zollinger-Ellison syndrome.

Medicinal Benefits of Oxirab O 4mg/20mg Tablet

ONDANSETRON+RABEPRAZOLE is used to treat nausea, vomiting, stomach ulcers, gastro-oesophageal reflux disease (GERD), heartburn and erosive oesophagitis. It contains Rabeprazole and Ondansetron. Rabeprazole is a proton pump inhibitor that blocks the action of the gastric proton pump that is responsible for acid production in the stomach. Ondansetron is an anti-emetic drug. It works by blocking the action of serotonin (chemical messenger) that triggers nausea and vomiting. Thus, collectively ONDANSETRON+RABEPRAZOLE prevents nausea and vomiting, reduces the amount of acid produced, heals the ulcers, and prevents new ulcers. ONDANSETRON+RABEPRAZOLE is also used to treat infections caused by Helicobacter pylori and Zollinger-Ellison syndrome.

Directions for Use

Tablet/Capsule: Swallow it as a whole with a glass of water. You can take ONDANSETRON+RABEPRAZOLE with or without food at regular intervals, as prescribed by the doctor. Do not crush, chew or break it.

Side Effects of Oxirab O 4mg/20mg Tablet

• Nausea
• Vomiting
• Constipation
• Headache
• Fatigue
• Diarrhoea
• Sore throat
• Abdominal pain

Similar Drugs

For informational purposes only. Consult a doctor before taking any medicines.

In-Depth Precautions and Warning

Drug Warnings

Let your doctor know if you are sensitive to ONDANSETRON+RABEPRAZOLE or its components. ONDANSETRON+RABEPRAZOLE should be used with caution and only under doctor’s supervision if you have stomach/intestinal problems, liver, kidney or heart diseases, recent abdominal surgery, risk of bone fractures and autoimmune diseases like lupus. Long term treatment with ONDANSETRON+RABEPRAZOLE may increase the risk of fractures of the hip, spine, and wrist. Hence, inform your doctor if you have osteoporosis, bone-related problems, or taking any corticosteroids before starting ONDANSETRON+RABEPRAZOLE. Rabeprazole in ONDANSETRON+RABEPRAZOLE may also cause low Vitamin B12 levels on long term usage. Hence let your doctor know if you have Vitamin B12 deficiency before starting ONDANSETRON+RABEPRAZOLE. Your doctor may also suggest antacids along with ONDANSETRON+RABEPRAZOLE for better treatment based on your medical conditions. Let your doctor know if you are pregnant or a nursing mother before starting ONDANSETRON+RABEPRAZOLE. Avoid alcohol intake while using ONDANSETRON+RABEPRAZOLE since it can increase acid production in the stomach.

Drug Interactions

Drug-Drug Interaction:

ONDANSETRON+RABEPRAZOLE may interact with pain killers (acetaminophen, tramadol, aspirin, ibuprofen), anti-anxiety (pregabalin, lorazepam, diazepam), antiparkinson medicine (apomorphine), anti-depressants (duloxetine, amitriptyline), blood thinners (clopidogrel), a drug used to treat hypothyroidism (levothyroxine), anti-HIV (atazanavir), antifungals (ketoconazole, itraconazole), anti-cancer drugs (methotrexate), and vitamins (cyanocobalamin).

Drug-Disease Interaction:

Brief your doctor if you have a medical history of stomach/intestinal problems, liver, kidney or heart diseases, recent abdominal surgery, risk of bone fractures, autoimmune diseases like lupus, and Vitamin B12 deficiency before starting ONDANSETRON+RABEPRAZOLE.

Safety Advice

ALCOHOL

Alcohol consumption may increase acid production in the stomach. It is advised to avoid alcohol intake to prevent any undesirable side effects of ONDANSETRON+RABEPRAZOLE and further worsening of your disease. Please consult your doctor for more information before using ONDANSETRON+RABEPRAZOLE.

PREGNANCY

ONDANSETRON+RABEPRAZOLE is not recommended for use in pregnancy since Ondansetron may cause harmful effects on the developing baby. It is advised to consult your doctor if you plan to conceive or already pregnant before starting ONDANSETRON+RABEPRAZOLE.

BREAST FEEDING

It is not known if ONDANSETRON+RABEPRAZOLE passes into breast milk. Please consult your doctor before taking ONDANSETRON+RABEPRAZOLE if you are a nursing mother.

DRIVING

ONDANSETRON+RABEPRAZOLE is probably safe to use and doesn’t affect driving. However, please do not drive or operate machines if you experience any side effects that affect your ability to drive.

LIVER

Let your doctor know if you have any history of liver diseases or hepatic impairment. Your doctor will weigh the benefits and potential risks before prescribing ONDANSETRON+RABEPRAZOLE.

KIDNEY

Let your doctor know if you have any history of kidney diseases. Your doctor will weigh the benefits and potential risks before prescribing ONDANSETRON+RABEPRAZOLE.