PRODUCT DETAILS

About Op-Zole D 10mg/20mg Capsule

DOMPERIDONE+OMEPRAZOLE belongs to a group of medicines called gastrointestinal agents used to treat heartburn, indigestion, epigastric pain, gastro-oesophageal reflux disease (GERD), peptic ulcers and Zollinger-Ellison syndrome. Gastroesophageal reflux disease (GERD) occurs when stomach acid frequently flows back into the food pipe (oesophagus). Peptic ulcers are sores that develop on the inner lining of the intestine and stomach. Zollinger-Ellison syndrome is characterised by the formation of tumours in the upper part of the small intestine, which leads to excess acid production.

DOMPERIDONE+OMEPRAZOLE is a combination of two drugs, namely: Omeprazole (proton pump inhibitor) and Domperidone (a dopamine antagonist). Omeprazole works by blocking the action of an enzyme called gastric proton pump, which is responsible for the production of acid Domperidone works by increasing the movements and contractions of stomach muscle. Together, DOMPERIDONE+OMEPRAZOLE helps in treating acidity.

Take DOMPERIDONE+OMEPRAZOLE 30-60minutes prior to food. Swallow DOMPERIDONE+OMEPRAZOLE as a whole with a glass of water; do not chew, or break the tablet. You are advised to take DOMPERIDONE+OMEPRAZOLE for as long as your doctor has prescribed it for you depending on your medical condition. In some cases, you may experience certain common side effects such as dry mouth, stomach pain, diarrhoea, headache, and flatulence. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Inform your doctor before taking DOMPERIDONE+OMEPRAZOLE if you have a history of gastrointestinal bleeding or intestinal obstruction. Talk to your doctor before taking DOMPERIDONE+OMEPRAZOLE if you have osteoporosis as DOMPERIDONE+OMEPRAZOLE may increase the risk of bone fractures on long-term treatment. Consult your doctor before taking DOMPERIDONE+OMEPRAZOLE if you are pregnant or planning for pregnancy. Avoid taking DOMPERIDONE+OMEPRAZOLE if you are breastfeeding as DOMPERIDONE+OMEPRAZOLE may pass into breast milk. DOMPERIDONE+OMEPRAZOLE may cause sleepiness, so drive only if you are alert. DOMPERIDONE+OMEPRAZOLE should not be given to children as safety has not been established. Avoid consuming alcohol along with DOMPERIDONE+OMEPRAZOLE as it could lead to increased drowsiness and can elevate the production of stomach acid.

Uses of Op-Zole D 10mg/20mg Capsule

Gastro-oesophageal reflux disease, peptic ulcers, and Zollinger-Ellison syndrome.

Medicinal Benefits of Op-Zole D 10mg/20mg Capsule

DOMPERIDONE+OMEPRAZOLE belongs to a group of medicines called gastrointestinal agents used to treat heartburn, indigestion, epigastric pain, gastro-oesophageal reflux disease (GERD), peptic ulcers, and Zollinger-Ellison syndrome. DOMPERIDONE+OMEPRAZOLE is a combination of two drugs, namely: Omeprazole (proton pump inhibitor) and Domperidone (a dopamine antagonist). Omeprazole works by blocking the action of an enzyme called gastric proton pump, which is responsible for the production of acid Domperidone works by increasing the movements and contractions of stomach muscle. Together, DOMPERIDONE+OMEPRAZOLE helps in treating acidity.

Directions for Use

Take DOMPERIDONE+OMEPRAZOLE 30-60minutes prior to food. Swallow DOMPERIDONE+OMEPRAZOLE as a whole with a glass of water; do not chew, or crush the tablet. Depending on your medical condition, your doctor will decide how long you need to take DOMPERIDONE+OMEPRAZOLE.

Side Effects of Op-Zole D 10mg/20mg Capsule

Like all medicines, DOMPERIDONE+OMEPRAZOLE can also cause side effects, although not everybody experiences them. Dry mouth, stomach pain, diarrhea, headache, and flatulence are the common side-effects of DOMPERIDONE+OMEPRAZOLE. Talk to your doctor if you experience any of these side effects persistently.

Similar Drugs

For informational purposes only. Consult a doctor before taking any medicines.

In-Depth Precautions and Warning

Drug Warnings

Do not take DOMPERIDONE+OMEPRAZOLE if you are allergic to any of its contents; if you are taking nelfinavir (anti-HIV); if you have a gastrointestinal hemorrhage, mechanical obstruction or perforation, epilepsy, mania, porphyria, or cardiac impairment. Inform your doctor before taking DOMPERIDONE+OMEPRAZOLE if you have severe liver or kidney problems; if you are due to have Chromogranin A test; if you experience unexplained weight loss, stomach pain, indigestion, vomit food or blood, or if you pass black stools. Talk to your doctor before taking DOMPERIDONE+OMEPRAZOLE if you have osteoporosis as DOMPERIDONE+OMEPRAZOLE may increase the risk of bone fractures on long-term treatment. Consult your doctor before taking DOMPERIDONE+OMEPRAZOLE if you are pregnant or planning for pregnancy. Avoid taking DOMPERIDONE+OMEPRAZOLE if you are breastfeeding as DOMPERIDONE+OMEPRAZOLE may pass into breast milk. DOMPERIDONE+OMEPRAZOLE may cause sleepiness, so drive only if you are alert. DOMPERIDONE+OMEPRAZOLE should not be given to children as safety has not been established. Avoid consuming alcohol along with DOMPERIDONE+OMEPRAZOLE as it could lead to increased drowsiness and can elevate the production of stomach acid.

Drug Interactions

Drug-Drug Interaction:

DOMPERIDONE+OMEPRAZOLE may have interaction with painkillers (aspirin), antibiotics (ciprofloxacin), statin (atorvastatin), anti-HIV (atazanavir), blood thinner (clopidogrel, warfarin, cilostazol), a drug used to treat hypothyroidism (levothyroxine), anti-fungal (ketoconazole, itraconazole, voriconazole), anti-cancer (erlotinib, methotrexate), anti-depressant (citalopram, escitalopram, duloxetine), anti-anxiety (alprazolam), vitamin (cyanocobalamin), anti-convulsant (phenytoin), gastroprokinetic agent (cisapride), a drug used to treat heart problems (digoxin), immunosuppressant (tacrolimus), anti-tuberculosis (rifampicin).

Drug-Disease Interaction:

DOMPERIDONE+OMEPRAZOLE may have interactions with epilepsy, mania, Clostridium difficile-associated diarrhea (CDAD), liver disease, bone fractures, and hypomagnesemia (low levels of magnesium).

Safety Advice

ALCOHOL

DOMPERIDONE+OMEPRAZOLE may have interactions with epilepsy, mania, Clostridium difficile-associated diarrhea (CDAD), liver disease, bone fractures, and hypomagnesemia (low levels of magnesium).

PREGNANCY

Consult your doctor before taking DOMPERIDONE+OMEPRAZOLE if you are pregnant; your doctor will prescribe only if the benefits outweigh the risks.

BREAST FEEDING

DOMPERIDONE+OMEPRAZOLE may pass into breast milk. Consult your doctor before taking DOMPERIDONE+OMEPRAZOLE; your doctor will decide whether DOMPERIDONE+OMEPRAZOLE can be taken by breastfeeding mothers or not.

DRIVING

DOMPERIDONE+OMEPRAZOLE may cause sleepiness. Do not drive or operate machinery unless you are alert.

LIVER

Dose adjustment may be needed. Consult your doctor before taking DOMPERIDONE+OMEPRAZOLE if you have a liver impairment or any concerns regarding this.

KIDNEY

Dose adjustment may be needed. Consult your doctor before taking DOMPERIDONE+OMEPRAZOLE if you have kidney impairment or any concerns regarding this.