PRODUCT DETAILS

About Megimine XL 750mcg/75mg Capsule

METHYLCOBALAMIN+PREGABALIN belongs to the class of medications ‘anticonvulsants’ used in the treatment of neuropathic pain. Neuropathic pain is a chronic (long-term) progressive nerve disease that causes nerve pain due to nerve damage or the nervous system's malfunctioning. It is mostly seen in patients who had suffered a trauma or nerve injury, diabetes, vitamin deficiencies, cancer, multiple sclerosis (disease of the brain and spinal cord), shingles (a viral infection), and HIV.

METHYLCOBALAMIN+PREGABALIN is a combination of two medicines: Pregabalin and Methylcobalamin. Pregabalin acts by decreasing the pain signal's number sent by a damaged nerve in the body. On the other hand, Methylcobalamin helps rejuvenate and protect damaged nerve cells by producing a substance called myelin (outer protective layer of nerve cell - neuron).

METHYLCOBALAMIN+PREGABALIN is available in the form of tablets. You should take this medicine as prescribed by your doctor. The common side-effects of METHYLCOBALAMIN+PREGABALIN are dizziness, drowsiness, headache, anorexia (loss of appetite), nausea or vomiting, diarrhea, headache, hot sensation (burning pain), vision problems, and diaphoresis (sweating). Inform your doctor if any of these side-effects persist.

Do not take METHYLCOBALAMIN+PREGABALIN if you are allergic to ‘Pregabalin’ and ‘Methylcobalamin’ or any contents before taking METHYLCOBALAMIN+PREGABALIN if you have a history of heart diseases, liver or kidney disease, alcoholism, or drug abuse.  It should not be used in children and adolescents below 18 years. Inform your doctor if you are pregnant and breastfeeding. Do not drive or operate heavy machinery as METHYLCOBALAMIN+PREGABALIN may cause dizziness or drowsiness. METHYLCOBALAMIN+PREGABALIN contains lactose, so inform your doctor if you have any intolerance to sugars. Do not discontinue treatment without telling your doctor. 

Uses of Megimine XL 750mcg/75mg Capsule

Neuropathic pain

Medicinal Benefits of Megimine XL 750mcg/75mg Capsule

METHYLCOBALAMIN+PREGABALIN is a combination of two drugs: Pregabalin and Methylcobalamin. Pregabalin is an anticonvulsant that affects the brain's chemicals that send pain signals across the nervous system. It works by binding to the specific site on voltage-gated calcium channels (responsible for excitatory response), thereby decreasing brain activity. This effect helps in relieving nerve pain and lowers the risk of seizures. On the other hand, Methylcobalamin is a form of vitamin B12 that helps rejuvenate and protect damaged nerve cells by producing a substance called myelin (outer protective layer of nerve cells). Together, METHYLCOBALAMIN+PREGABALIN helps in providing relief from neuropathic pain and improved nerve signal conduction.

Directions for Use

METHYLCOBALAMIN+PREGABALIN is available in the form of tablets. Tablet: Swallow METHYLCOBALAMIN+PREGABALIN tablet as a whole with a glass of water, do not chew, or break the tablet. Your doctor will decide the dose and how long you need to take METHYLCOBALAMIN+PREGABALIN based on your medical condition.

Side Effects of Megimine XL 750mcg/75mg Capsule

• Dizziness
• Drowsiness
• Headache
• Anorexia (loss of appetite)
• Nausea or vomiting
• Diarrhea
• Headache
• Sore throat
• Vision problems
• Hot sensation (burning pain)
• Diaphoresis (sweating)
• Weight gain

Similar Drugs

For informational purposes only. Consult a doctor before taking any medicines.

In-Depth Precautions and Warning

Drug Warnings

METHYLCOBALAMIN+PREGABALIN may increase the risk of heart failure in patients with heart diseases. It may cause dizziness and somnolence (sleepiness). So, it might increase the risk of accidental injury in elderly patients. METHYLCOBALAMIN+PREGABALIN may also cause temporary vision problems. However, if this condition is persistent, consult your doctor immediately. Patients with diabetes who gain weight with METHYLCOBALAMIN+PREGABALIN may need a change in diabetic medicines. If you notice decreased urination while taking METHYLCOBALAMIN+PREGABALIN, inform your doctor as METHYLCOBALAMIN+PREGABALIN may cause kidney failure in some cases. It may increase suicidal tendencies, though it is rare. You may experience convulsions after discontinuing METHYLCOBALAMIN+PREGABALIN. In such cases, inform your doctor immediately.  

Drug Interactions

Drug-Drug Interaction:

METHYLCOBALAMIN+PREGABALIN may interact with a pain killer (oxycodone), opioids, and antianxiety drug (lorazepam), antacid (omeprazole), antibiotic (neomycin), and anti-gout medication (colchicine). 

Drug-Disease Interaction:

METHYLCOBALAMIN+PREGABALIN should be used with caution in patients with liver diseases, kidney diseases, heart problems, alcoholism, drug abuse, and suicidal tendencies. 

Safety Advice

ALCOHOL

Alcohol may worsen the condition by increasing the risk of side-effects.

PREGNANCY

METHYLCOBALAMIN+PREGABALIN is a category C medicine. It is not recommended for use in pregnant women unless the doctor thinks the benefits outweigh the risks.

BREAST FEEDING

METHYLCOBALAMIN+PREGABALIN should be used with caution in breastfeeding mothers unless the doctor thinks the benefits outweigh the risks.

DRIVING

METHYLCOBALAMIN+PREGABALIN may cause dizziness and drowsiness. So, avoid driving or operating heavy machinery while using METHYLCOBALAMIN+PREGABALIN.

LIVER

METHYLCOBALAMIN+PREGABALIN should be used with caution in patients with liver diseases. Dose adjustments may be necessary.

KIDNEY

METHYLCOBALAMIN+PREGABALIN should be used with caution in patients with kidney diseases. Dose adjustments may be necessary