PRODUCT DETAILS

About Januvia 100mg Tablet

SITAGLIPTIN contains Sitagliptin which belongs to the class of dipeptidyl peptidase-4 (DPP-4) inhibitors used in the treatment of type 2 diabetes in adults. SITAGLIPTIN is prescribed for the condition of type 2 diabetes when diet and exercise alone cannot control their blood sugar levels. It is the first-line therapy for patients with type 2 diabetes that restores the body's response to insulin. Insulin is the hormone that controls sugar levels in your blood. People with type 2 diabetes either do not produce enough insulin or the insulin produced is unable to perform its function in the body (insulin resistance). Middle-aged or older individuals are most likely to suffer from type 2 diabetes, so it is also known as adult-onset diabetes.

SITAGLIPTIN should not be used in patients with type 1 diabetes and for the treatment of diabetic ketoacidosis. SITAGLIPTIN work by blocking the action of DPP-4 (an enzyme which destroys hormone ‘Incretin’). The enzyme ‘Incretins’ help to produce more insulin only when required and reduce blood sugar level produced by the liver when not needed.

Uses of Januvia 100mg Tablet

Type 2 diabetes mellitus

Medicinal Benefits of Januvia 100mg Tablet

SITAGLIPTIN work by blocking the action of DPP-4 (an enzyme which destroys hormone ‘Incretin’). The enzyme ‘Incretins’ help to produce more insulin only when required and reduce blood sugar level produced by the liver when not needed. Thus, SITAGLIPTIN plays a vital role in controlling blood sugar levels and prevents serious complications of diabetes like eyesight loss (retinopathy), kidney (nephropathy), nerve damage (neuropathy), diabetic foot ulcer and delayed wound healing.

Directions for Use

The recommended dose of SITAGLIPTIN is 100 mg once daily. It can be taken with or without food. Prior dosage adjustment may be recommended for patients with moderate or severe kidney disease or end-stage kidney disease.

Side Effects of Januvia 100mg Tablet

Every medicine has some sort of side effects. In the beginning days of the treatment with SITAGLIPTIN, you may suffer from hypoglycaemia (low blood glucose levels), upper respiratory tract infection, nasopharyngitis (infection of nose and throat with common cold) and headache. But these would be temporary and may be relieved after some time. However, if you still have discomfort speak with the doctor.

Similar Drugs

For informational purposes only. Consult a doctor before taking any medicines.

In-Depth Precautions and Warning

Drug-Drug Interaction:

SITAGLIPTIN interacts with an anti-depressant (bupropion), drugs used to treat glaucoma, antibiotics (cephalexin, ciprofloxacin), anti-acidity drugs (cimetidine), heart condition drugs (digoxin), anti-HIV drugs (dolutegravir), ethanol, saliva reducing drugs (glycopyrrolate), iodinated X-ray contrast agents, anti-epileptic drugs (topiramate, lamotrigine), heart-related chest medicine (ranolazine). Other drug interactions can contribute to an increased low blood sugar including sex hormones (androgens), anti-oxidant (alpha-lipoic acid), painkillers (aspirin), anti TB drugs (prothionamide), growth hormones (pegvisomant), and other antidiabetic medicines.

Safety Advice

ALCOHOL

Yes, you can drink alcohol while taking SITAGLIPTIN. but while drink more than 175ml can increase your risk of low blood sugar.

 

DRIVING

SITAGLIPTIN has no influence on the ability to drive and use machines. However, dizziness and drowsiness have been reported, which may affect your ability to drive or use machines.

 

LIVER

Rare cases of liver enzyme elevations have been reported in the prolonged usage of SITAGLIPTIN.

KIDNEY

Acute renal failure has been reported in the patients taking SITAGLIPTIN. In severe cases, sometimes requiring dialysis. Hence, dosage adjustment can be recommended in patients with moderate or severe kidney disease and in patients with kidney failure (also known as ESRD - end stage renal dialysis).