PRODUCT DETAILS

About Isobitol 300mg/800mg Tablet

ETHAMBUTOL+ISONIAZID belongs to the group of medications called ‘antituberculosis agents’ primarily used in the treatment of tuberculosis (TB). Tuberculosis is an infectious bacterial disease that mainly affects the lungs, but it can also spread to other body parts such as kidneys, brain, spine and bone marrow. ETHAMBUTOL+ISONIAZID does not work against infections caused by the virus.

ETHAMBUTOL+ISONIAZID contains Isoniazid and Ethambutol. They are bacteriostatic agents (stop the growth of bacteria) and have a similar mode of action. They work by preventing mycolic acid production (an enzyme produced by bacteria) essential for cell wall formation (protective coating). Thereby, bacteria get killed without a cell wall and burst due to disruption in their metabolism.

Uses of Isobitol 300mg/800mg Tablet

Tuberculosis

Medicinal Benefits of Isobitol 300mg/800mg Tablet

ETHAMBUTOL+ISONIAZID contains Isoniazid and Ethambutol, which is a fixed-dose combination used to treat tuberculosis (TB). Combination therapy reduces the development of drug resistance (reduction in the effectiveness of medication) as the bacteria causing TB develops drug resistance easily when monotherapy is given even for shorter periods. ETHAMBUTOL+ISONIAZID helps to reduce the symptoms and control the disease effectively.

Directions for Use

ETHAMBUTOL+ISONIAZID is available in the form of a tablet. The tablet should be swallowed as a whole with a glass of water. Do not crush, chew or break the tablet. The dose and duration are determined by the doctor based on your health condition. It is advised to take a ETHAMBUTOL+ISONIAZID tablet on an empty stomach. The ideal time to take ETHAMBUTOL+ISONIAZID is at least one hour before breakfast or snack or after two hours of a meal. Take it at the same time every day for the best results.

Side Effects of Isobitol 300mg/800mg Tablet

• Weakness
• Malaise (general discomfort)
• Fatigue (feeling tired)
• Loss of appetite
• Nausea or vomiting
• Dark urine
• Pale stools
• Jaundice (yellowing of the skin or whites of the eyes)
  • Vision problems

Similar Drugs

For informational purposes only. Consult a doctor before taking any medicines.

In-Depth Precautions and Warning

Drug Warnings

It is advised to get your eyesight checked before taking ETHAMBUTOL+ISONIAZID. If you notice any changes in your vision while using this medicine, stop taking this medicine and immediately inform your doctor. In most cases, the vision change is temporary and sight returns to normal. However, it might take a longer time for eyesight to recover in some cases or the change might be permanent. If you develop jaundice (yellowing of the skin and whites of the eyes), loss of appetite, nausea, vomiting, or malaise, inform your doctor immediately, as these effects may be a sign of hepatitis (liver disease). In these cases, the doctor may advise you to undergo liver function tests and provide the necessary treatment.

Drug Interactions

Drug-Drug Interaction:

ETHAMBUTOL+ISONIAZID may interact with antacid (aluminium hydroxide), anti-HIV drug (stavudine), medicines used to treat fits (carbamazepine, phenytoin, and primidone), a medicine used to treat alcoholism (disulfiram), other antitubercular drugs (rifampicin and para-aminosalicylic acid), an anti-anxiety medication (diazepam), a medicine used to treat Parkinson’s disease (levodopa), and antifungal drugs (itraconazole and ketoconazole).

Drug-Disease Interaction:

ETHAMBUTOL+ISONIAZID is not recommended for use in patients with severe liver problems and eyesight problems. It should be used with caution in patients with kidney problems, epilepsy (fits), diabetes, alcohol abuse, psychosis, malnourishment, HIV infection and extra-pulmonary TB (TB infection outside the lungs).

Safety Advice

ALCOHOL

Consumption of alcohol may increase the risk of side-effects and worsen the condition.

PREGNANCY

ETHAMBUTOL+ISONIAZID should be used with caution in pregnant women. It is given to pregnant women only if clinically needed when the benefits outweigh the risks.

BREAST FEEDING

ETHAMBUTOL+ISONIAZID should be used with caution in breastfeeding mothers. It is given to breastfeeding mothers only when the benefits outweigh the risks.

DRIVING

ETHAMBUTOL+ISONIAZID may cause dizziness in some people. So, do not drive or operate heavy machinery if you are not fully alert.

LIVER

ETHAMBUTOL+ISONIAZID is not recommended for patients with severe liver problems. In mild to moderate liver diseases, the dose may have to be adjusted by your doctor.

KIDNEY

ETHAMBUTOL+ISONIAZID should be used with caution in patients with kidney diseases. The dose may have to be adjusted by your doctor.