PRODUCT DETAILS

About Estcom 40mg Injection

PIROXICAM belongs to the group of medications known as NSAID's (Non-Steroidal Anti-Inflammatory Drugs) used to relieve symptoms like pain, inflammation and joint stiffness caused by rheumatoid arthritis and osteoarthritis. Osteoarthritis is a degenerative joint disease in which the two ends of the joints come together due to the breakdown of a protective covering (cartilage). Due to the absence of this protective covering, the joints rub against each other, leading to pain and stiffness. Rheumatoid arthritis is an auto-immune disease (body's immune system attacks its tissue), leading to joint pain and damage.

PIROXICAM works by blocking the effect of a chemical messenger in your body, known as cyclo-oxygenase (COX) enzymes that make another chemical 'prostaglandins' (PG). These prostaglandins are produced at injury sites and cause pain and swelling. By blocking the effect of COX enzymes, lesser PGs are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site.

Uses of Estcom 40mg Injection

Osteoarthritis, Rheumatoid arthritis

Medicinal Benefits of Estcom 40mg Injection

PIROXICAM belongs to the group of pain killers known as NSAID's (Non-Steroidal Anti-Inflammatory Drugs). PIROXICAM is used to relieve symptoms caused by osteoarthritis, and rheumatoid arthritis, such as stiffness, swelling, and joint pain. PIROXICAM works by blocking the effect of a chemical messenger in your body, known as cyclo-oxygenase (COX) enzymes that make another chemical 'prostaglandins' (PG). These prostaglandins are produced at injury sites and cause pain and swelling. By blocking the effect of COX enzymes, fewer PGs are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site.

Directions for Use

Take PIROXICAM with or after food. Capsule: Do not chew, break, or crush the capsule; swallow it as a whole with a glass of water. Take PIROXICAM at the same time every day. Injection: PIROXICAM will be administered by a healthcare professional. Do not self-administer.

Side Effects of Estcom 40mg Injection

In some cases, you may experience certain common side-effects such as diarrhoea, dizziness, headache and heartburn. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to speak to your doctor if you experience these side-effects persistently.

Similar Drugs

For informational purposes only. Consult a doctor before taking any medicines.

In-Depth Precautions and Warning

Drug Warnings

PIROXICAM may increase the risk of serious heart-related problems, like heart attack and stroke. So, if you are a heart patient, let your doctor know before taking PIROXICAM. Besides this, PIROXICAM also cause bleeding and ulcer in the intestine and stomach, so let your doctor know if you have these problems. Do not take PIROXICAM for pain after a heart bypass surgery or coronary artery bypass graft surgery (CABG) as it can increase your risk of a heart attack or stroke. Consult your doctor before taking PIROXICAM if you are pregnant or breast-feeding; your doctor will prescribe you PIROXICAM only if the benefits outweigh the risks. PIROXICAM causes drowsiness and dizziness, so drive only if you are alert. PIROXICAM should not be given to children as safety has not been established. Avoid consuming alcohol along with PIROXICAM as it could lead to increased drowsiness and can increase the risk of stomach bleeding. Do not take aspirin or any other pain killers like aspirin for pain relief or warfarin or any other anticoagulants (used to prevent blood clotting) along with PIROXICAM, to avoid the risk of bleeding problems. Tell your doctor before taking PIROXICAM if you have asthma, water retention (oedema) or high blood pressure, as taking PIROXICAM in these conditions can worsen these diseases.

Drug Interactions

Drug-Drug Interaction:

 PIROXICAM may have interaction with ibuprofen, naproxen, and aspirin (used to relieve pain), duloxetine (used to treat depression), metoprolol, atenolol, and lisinopril (used to treat high blood pressure), warfarin (used to prevent blood clotting), celecoxib, prednisone, and meloxicam (used to treat arthritis), sertraline (used to treat depression), and drugs used to treat high blood pressure and fluid retention.

Drug-Disease Interaction:

PIROXICAM should not be given in patients with heart failure, fluid retention (edema), asthma, gastrointestinal ulcer/bleeding, high blood pressure, hyperkalemia (high levels of potassium), thrombosis (formation of clots), anemia (low red blood cells), rash, platelet aggregation inhibition, kidney and liver problems.

Safety Advice

ALCOHOL

You are recommended to avoid alcohol consumption while taking PIROXICAM. Alcohol intake, along PIROXICAM may cause increased drowsiness and drowsiness. It may also cause increase in the risk of stomach/intestine ulcer and bleeding.

PREGNANCY

It is not recommended to take PIROXICAM while you are pregnant. Please consult your doctor if you have any concerns regarding this; your doctor will prescribe you PIROXICAM only if the benefits outweigh the risks.

BREAST FEEDING

It is not recommended to take PIROXICAM while you are breastfeeding. Please consult your doctor if you have any concerns regarding this; your doctor will decide whether PIROXICAM can be given to breast-feeding mothers or not.

DRIVING

PIROXICAM may cause drowsiness, dizziness, tiredness, and vision disturbances, do not drive or operate heavy machinery if you feel dizzy.

LIVER

Dose adjustment may be needed. PIROXICAM should be used with caution in patients with liver impairment/liver disease. Please consult your doctor if you have a liver impairment or any concerns regarding this.

KIDNEY

Dose adjustment may be needed. PIROXICAM should be used with caution in patients with kidney impairment/kidney disease. Please consult your doctor if you have kidney impairment or any concerns regarding this.