PRODUCT DETAILS

About Defnip 30 Tablet

DEFLAZACORT belongs to the class of medication called steroids primarily used to treat Duchene muscular dystrophy in adults and children above 2 years of age. Autoimmune disease is a health disorder in which the immune system doesn't work normally & is unable to distinguish between a foreign cell & a native cell. This condition results in an immune system that starts to attack native cells & organs, leading to medical problems like Duchenne muscular dystrophy, psoriasis & arthritis, etc.

DEFLAZACORT is an immunosuppressive drug that works by binding to immune system cells and turns off the switches (receptors) that lead to their abnormal functioning or damaging effects. After taking the drug DEFLAZACORT binds to immune cells, resulting in the inhibition of inflammation & autoimmune diseases that occur due to the production of chemicals called cytokines responsible for inflammation. Thus, a DEFLAZACORT class of drugs is beneficial in autoimmune diseases and inflammation that causes harm in various organs, especially in joints in arthritis & skin psoriasis. DEFLAZACORT makes organ transplantation possible & treats muscle disorders like Duchenne muscular dystrophy.

DEFLAZACORT is available in both oral tablet and suspension dosage forms. The tablet form of DEFLAZACORT can be taken with or without food and swallowed whole with a water glass. Do not crush, chew or break it. The liquid form of DEFLAZACORT can be taken as advised by your doctor with a measuring cup. Your doctor will recommend how often you take DEFLAZACORT based on your medical condition. Some people may experience nausea, chest pain, vomiting, drowsiness, headache, dizziness, skin rash, tremor, nervousness, diarrhea, and fast heartbeats. Most of these side effects of DEFLAZACORT do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor. Do not quit taking deflazacort without consulting your physician. Symptoms such as loss of appetite, a disturbed stomach, vomiting, drowsiness, confusion, headache, fever, joint and muscle pain, peeling skin, and weight loss may be caused by stopping the medication suddenly.

Before starting DEFLAZACORT, please inform your doctor that you are allergic (hypersensitive) to DEFLAZACORT. Extra care is to be taken when a patient has an already existing infection being treated (systemic infection) or has recently had some live virus vaccines. Doctors' consultation is required as DEFLAZACORT is not safe to use during pregnancy. 

Uses of Defnip 30 Tablet

Duchenne muscular dystrophy (DMD) 

Medicinal Benefits of Defnip 30 Tablet

DEFLAZACORT is beneficial in inflammatory diseases, including asthma, arthritis, and allergies. It is used in the treatment of Duchenne muscular dystrophy (DMD). It raises the number of glucocorticoids in the body. It works by reducing the formation of inflammatory substances and suppressing immunity to prevent self-damage caused by the immune system (auto-immune reactions occurring in organ transplants, autoimmune diseases, or cancer). DEFLAZACORT is a steroid that interacts with overactive immune cells and slows their activity and decreases the damaging effects they cause in the body. 

Directions for Use

Swallow the tablet whole with a glass of water at the start of a meal or slightly before. Space the doses evenly during the course. Do not chew or crush it. If you cannot swallow the tablet as a whole, you may break the pill into half and take both halves one at a time.

Side Effects of Defnip 30 Tablet

Most of the side effects of DEFLAZACORT do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor. Common side effects include upper respiratory tract infection, excessive abdominal fat, runny or stuffy nose, skin redness, irritability, abdominal discomfort or pain, irregular behavior, fever, back pain, acne, nausea, restlessness, nosebleeds, and stretch marks.

Similar Drugs

For informational purposes only. Consult a doctor before taking any medicines.

In-Depth Precautions and Warning

Drug Warnings

Patients with a history of tuberculosis (TB), heart disease or heart failure stomach disorders (gastritis, peptic ulcer), diabetes (including family history), osteoporosis (bone disease), myasthenia gravis (muscle weakness), depression, mental distress, history of muscular problems caused by corticosteroids, kidney & liver dysfunction (including hepatic insufficiency and cirrhosis), should consult a doctor before using DEFLAZACORT.  This medicine is not recommended for children less than 5 years of age, lactating mothers, and pregnant women. Avoid going near people who are sick or infected while using DEFLAZACORT. Before taking DEFLAZACORT for at least, 4-6 weeks do not take any live vaccine as it may cause severe allergic reactions. 

Drug Interactions

Drug-Drug Interaction:

DEFLAZACORT interacts with anti-tuberculosis (anti TB) drugs like rifampicin, rifabutin, pain-relieving drugs like carbamazepine, and Anti-seizure drugs like phenobarbitone, phenytoin & pyrimidine & antifungal like ketoconazole.

Drug-Disease Interaction:

  Care should be exercised when DEFLAZACORT is administered in patients with diabetes, cataracts, Thyroidism, blood pressure, kidney diseases, glaucoma & herpes.

Safety Advice

ALCOHOL

The effect of taking both alcohol and DEFLAZACORT may lead to bleeding & ulcers in the stomach. Doctors' consultation is recommended.

PREGNANCY

Not recommended in pregnant females.DEFLAZACORT crosses the placenta and doses equivalent to >40 mg prednisolone daily increase the risk of fetal and neonatal damage.

BREAST FEEDING

No adverse effect is reported yet it is advised to have a doctor's consultation with breastfeeding mothers.

DRIVING

A patient may experience muscle weakness/feeling tired. Do not drive and do not use tools or machines while using this drug.

LIVER

If you've ever had hepatitis B or if you are a carrier of hepatitis B, using DEFLAZACORT can cause this virus to become active or get worse. You may need frequent liver function tests. If you need surgery, tell the surgeon ahead of time that you are using DEFLAZACORT.

KIDNEY

Before using DEFLAZACORT by a kidney patient it is recommended to have a doctor's consultation. It may affect the kidney in a few cases.