PRODUCT DETAILS

About D Zire 20mg Tablet

DULOXETINE belongs to a group of medicines known as 'Antidepressants' It is primarily used for the treatment of depression and anxiety. Besides this, it is also used to treat neuropathic pain such as fibromyalgia associated with diabetic peripheral neuropathy and can be used to treat stress urinary incontinence in women. Depression is a mental illness or disorder characterized by persistently depressed mood or loss of interest in activities, causing significant impairment in daily life. Anxiety is a feeling of unease, such as worry or fear that can be mild or severe. Fibromyalgia also called fibromyalgia syndrome (FMS), is a long-term condition that causes pain all over the body. Urinary incontinence is the unintentional passing of urine. It's a common problem thought to affect millions of people.

Being an antidepressant, DULOXETINE is a serotonin-noradrenaline reuptake inhibitor (SNRI). It works by enhancing the amount of mood-enhancing chemicals serotonin and noradrenaline in the brain. This action of DULOXETINE balance out negative emotions and improves mood, sleep, and makes a person live a better life. In this way, DULOXETINE gives relief to depressive disorder, anxiety disorder, neuropathic pain, fibromyalgia, and many more.

Depending upon the health condition of the patient, the doctor will suggest different dosing strengths of DULOXETINE to the patient. This medicine is available in capsule form that needs to be swallowed as a whole without breaking or chewing or opening it. It may take about 4 weeks to see any improvement in the symptoms. A person's blood pressure needs to be checked more often while taking DULOXETINE. 

Seek medical attention immediately if you notice any serious allergic reaction such as sore throat, fever, hives, difficult breathing, etc after taking the DULOXETINE. Common side effects of the medicine include drowsiness, nausea, constipation, dry mouth, increased sweating, etc. A person taking this drug is not allowed to stop or reduce the dosage even if they start noticing an improvement in their condition without asking their doctor as it may cause unpleasant symptoms including vomiting, agitation, confusion, etc. 

One should avoid drinking alcohol while taking this medicine as it may increase the risk of liver damage.  The use of DULOXETINE is not allowed within 5 days before or 14 days if you have used an MAO inhibitor, like methylene blue injection, phenelzine, selegiline, or tranylcypromine. It may result in serious drug interaction. Stay attentive to the mood changes or symptoms and do not drive.

Uses of D Zire 20mg Tablet

Major depressive disorder, anxiety disorder, neuropathic pain associated with diabetes, chronic muscle or joint pain, fibromyalgia

Medicinal Benefits of D Zire 20mg Tablet

DULOXETINE is used in the treatment of depression and anxiety disorders. This medicine is also used to relieve nerve pain associated with diabetic neuropathy or chronic pain associated with arthritis or back pain. This medicine acts by restoring the balance of serotonin and norepinephrine, a natural chemical present in the brain. In this way, this drug improves mood, appetite, sleep, and energy levels in patients and gives a sense of calmness in the body.

Directions for Use

Depending upon the condition to be treated, the doctor will prescribe the dosing strength accordingly. DULOXETINE is available in capsule form, so take it as a whole without crushing, chewing, breaking, or opening. Do not increase or decrease the dose to get the results fast as increasing the dosage may cause side effects. This medicine can be taken with or without food however taking it without a meal or light meal helps more effectiveness. This medicine will take about 4 weeks to improve the symptoms however one should keep taking it even if they are feeling well until their doctor ask them to stop. Stopping the medicine suddenly may lead to side effects including vomiting, agitation, sweating, dizziness, confusion, numbness, and tingling. In case of stopping the medication, it is better to consult with the doctor as they will slightly lower the dose before completely stopping it.

Side Effects of D Zire 20mg Tablet

Along with desired beneficial effects, DULOXETINE may cause side effects including drowsiness, fatigue, hypersomnia, insomnia, nausea, constipation, diarrhea, body aches or pain, cough, dry mouth, frequent urination, headache, loss of appetite, muscle aches, sleepiness, sneezing, dizziness, headache, etc. However, some of the side effects do not require any medical help. These side effects will go with time, and it happens initially because the body is adjusting to the new medication and will settle down with time. Seek medical attention immediately if you notice any serious allergic reaction such as sore throat, fever, hives, difficult breathing, etc. after taking the DULOXETINE.

Similar Drugs

For informational purposes only. Consult a doctor before taking any medicines.

In-Depth Precautions and Warning

Drug Warnings

DULOXETINE should not be allowed to be used within 5 days before or 14 days after taking an MAO inhibitor such as rasagiline, selegiline, or linezolid as it may result in serious drug interaction. Don't stop taking DULOXETINE without consulting with a doctor as it may cause serious drug with drawl symptoms. At the time of consultation, tell your doctor about heart problems, high blood pressure, liver or kidney disease, slow digestion, and a seizure. You should tell your doctor if you are pregnant or breastfeeding with your doctor.  Avoid doing any hazardous activity as these medicines cause sleepiness in the body so take rest only.

Drug Interactions

Drug-Drug Interaction:

Tell all the medications you are taking to your doctor as this medicine may interact with other drugs including antiplatelet drugs such as clopidogrel, 'blood thinners' such as warfarin, and NSAIDs such as ibuprofen, certain quinolone antibiotics such as ciprofloxacin, MAO inhibitors such as linezolid, etc.

Drug-Disease Interaction:

Tell your doctor about your past medical history and other ongoing diseases if you have any, as the use of medicine is restricted in some conditions that include: manic-depression, suicidal thoughts, alcoholism, serotonin syndrome, closed-angle glaucoma, high blood pressure, orthostatic hypotension, a form of low blood pressure, chronic inflammation of the liver, etc.

Safety Advice

ALCOHOL

Taking the drug along with alcohol may increase the side effects such as confusion, drowsiness, and trouble in concentrating. A few people may find it difficult in doing mental tasks. A person needs to limit the use of alcohol while being treated with this medicine.

PREGNANCY

DULOXETINE is only suggested to use in pregnancy if suggested by the doctor. This medicine increases the risk of deformities in infants so one should tell their doctor if they are pregnant.

BREAST FEEDING

DULOXETINE can pass into breast milk so one should tell their doctor if they are breastfeeding their child. The use of DULOXETINE is only allowed in breastfeeding if suggested by the doctor.

DRIVING

DULOXETINE can cause sleepiness or may affect a person's ability to drive so one should avoid driving or doing any work that needs clear attention.

LIVER

DULOXETINE is restricted to use in patients dealing with liver disease. Tell your doctor if you have any preexisting liver disease.

KIDNEY

DULOXETINE is not approved to use in patients dealing with severe kidney disease.